PDB entry 3e7b

View 3e7b on RCSB PDB site
Description: Crystal Structure of Protein Phosphatase-1 Bound to the natural toxin inhibitor Tautomycin
Class: hydrolase
Keywords: protein phosphatase 1, tautomycin, molecular toxin, Carbohydrate metabolism, Cell cycle, Cell division, Glycogen metabolism, Hydrolase, Iron, Manganese, Metal-binding, Phosphoprotein
Deposited on 2008-08-18, released 2008-11-04
The last revision prior to the SCOPe 2.08 freeze date was dated 2017-10-25, with a file datestamp of 2017-10-20.
Experiment type: XRAY
Resolution: 1.7 Å
R-factor: N/A
AEROSPACI score: 0.4 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: Serine/threonine-protein phosphatase PP1-alpha catalytic subunit
    Species: Homo sapiens [TaxId:9606]
    Gene: PPP1CA, PPP1A
    Database cross-references and differences (RAF-indexed):
    • Uniprot P62136 (5-End)
      • expression tag (4)
    Domains in SCOPe 2.08: d3e7ba1, d3e7ba2
  • Chain 'B':
    Compound: Serine/threonine-protein phosphatase PP1-alpha catalytic subunit
    Species: Homo sapiens [TaxId:9606]
    Gene: PPP1CA, PPP1A
    Database cross-references and differences (RAF-indexed):
    • Uniprot P62136 (5-End)
      • expression tag (4)
    Domains in SCOPe 2.08: d3e7bb1, d3e7bb2
  • Heterogens: MN, E7B, CL, GOL, NA, AZI, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download) 
    >3e7bA (A:)
ghmgslnldsiigrllevqgsrpgknvqlteneirglclksreiflsqpilleleaplki
cgdihgqyydllrlfeyggfppesnylflgdyvdrgkqsleticlllaykikypenffll
rgnhecasinriygfydeckrryniklwktftdcfnclpiaaivdekifcchgglspdlq
smeqirrimrptdvpdqgllcdllwsdpdkdvqgwgendrgvsftfgaevvakflhkhdl
dlicrahqvvedgyeffakrqlvtlfsapnycgefdnagammsvdetlmcsfqilkpad

    Sequence, based on observed residues (ATOM records): (download) 
    >3e7bA (A:)
slnldsiigrllevqgsrpgknvqlteneirglclksreiflsqpilleleaplkicgdi
hgqyydllrlfeyggfppesnylflgdyvdrgkqsleticlllaykikypenffllrgnh
ecasinriygfydeckrryniklwktftdcfnclpiaaivdekifcchgglspdlqsmeq
irrimrptdvpdqgllcdllwsdpdkdvqgwgendrgvsftfgaevvakflhkhdldlic
rahqvvedgyeffakrqlvtlfsapnycgefdnagammsvdetlmcsfqilkpa

  • Chain 'B':
    Sequence, based on SEQRES records: (download) 
    >3e7bB (B:)
ghmgslnldsiigrllevqgsrpgknvqlteneirglclksreiflsqpilleleaplki
cgdihgqyydllrlfeyggfppesnylflgdyvdrgkqsleticlllaykikypenffll
rgnhecasinriygfydeckrryniklwktftdcfnclpiaaivdekifcchgglspdlq
smeqirrimrptdvpdqgllcdllwsdpdkdvqgwgendrgvsftfgaevvakflhkhdl
dlicrahqvvedgyeffakrqlvtlfsapnycgefdnagammsvdetlmcsfqilkpad

    Sequence, based on observed residues (ATOM records): (download) 
    >3e7bB (B:)
slnldsiigrllevqgsrpgknvqlteneirglclksreiflsqpilleleaplkicgdi
hgqyydllrlfeyggfppesnylflgdyvdrgkqsleticlllaykikypenffllrgnh
ecasinriygfydeckrryniklwktftdcfnclpiaaivdekifcchgglspdlqsmeq
irrimrptdvpdqgllcdllwsdpdkdvqgwgendrgvsftfgaevvakflhkhdldlic
rahqvvedgyeffakrqlvtlfsapnycgefdnagammsvdetlmcsfqilkpa