PDB entry 3e77

View 3e77 on RCSB PDB site
Description: Human phosphoserine aminotransferase in complex with PLP
Class: transferase
Keywords: Phosphoserine aminotransferase, SERC, PLP, Structural Genomics, Structural Genomics Consortium, SGC, Amino-acid biosynthesis, Aminotransferase, Disease mutation, Pyridoxal phosphate, Serine biosynthesis, Transferase
Deposited on 2008-08-18, released 2008-08-26
The last revision prior to the SCOPe 2.03 freeze date was dated 2011-07-13, with a file datestamp of 2011-05-08.
Experiment type: XRAY
Resolution: 2.5 Å
R-factor: 0.199
AEROSPACI score: 0.32 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: phosphoserine aminotransferase
    Species: Homo sapiens [TaxId:9606]
    Gene: PSAT1, PSA
    Database cross-references and differences (RAF-indexed):
    • Uniprot Q9Y617 (23-376)
      • expression tag (14-22)
    Domains in SCOPe 2.03: d3e77a_
  • Chain 'B':
    Compound: phosphoserine aminotransferase
    Species: Homo sapiens [TaxId:9606]
    Gene: PSAT1, PSA
    Database cross-references and differences (RAF-indexed):
    • Uniprot Q9Y617 (23-376)
      • expression tag (15-22)
    Domains in SCOPe 2.03: d3e77b_
  • Chain 'C':
    Compound: phosphoserine aminotransferase
    Species: Homo sapiens [TaxId:9606]
    Gene: PSAT1, PSA
    Database cross-references and differences (RAF-indexed):
    • Uniprot Q9Y617 (23-End)
      • expression tag (14-22)
    Domains in SCOPe 2.03: d3e77c_
  • Heterogens: PLP, GOL, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download) 
    >3e77A (A:)
mhhhhhhssgvdlgtenlyfqsmlphsvlleiqkelldykgvgisvlemshrssdfakii
nntenlvrellavpdnykviflqgggcgqfsavplnliglkagrcadyvvtgawsakaae
eakkfgtinivhpklgsytkipdpstwnlnpdasyvyycanetvhgvefdfipdvkgavl
vcdmssnflskpvdvskfgvifagaqknvgsagvtvvivrddllgfalrecpsvleykvq
agnsslyntppcfsiyvmglvlewiknnggaaameklssiksqtiyeiidnsqgfyvcpv
epqnrskmnipfrignakgddalekrfldkalelnmlslkghrsvggiraslynavtied
vqklaafmkkflemhql

    Sequence, based on observed residues (ATOM records): (download) 
    >3e77A (A:)
tenlyfqsmlphsvlleiqkelldykgvgisvlemshrssdfakiinntenlvrellavp
dnykviflqgggcgqfsavplnliglkagrcadyvvtgawsakaaeeakkfgtinivhpk
lgsytkipdpstwnlnpdasyvyycanetvhgvefdfipdvkgavlvcdmssnflskpvd
vskfgvifagaqknvgsagvtvvivrddllgfalrecpsvleykvqagnsslyntppcfs
iyvmglvlewiknnggaaameklssiksqtiyeiidnsqgfyvcpvepqnrskmnipfri
gnakgddalekrfldkalelnmlslkghrsvggiraslynavtiedvqklaafmkkflem
hql

  • Chain 'B':
    Sequence, based on SEQRES records: (download) 
    >3e77B (B:)
mhhhhhhssgvdlgtenlyfqsmlphsvlleiqkelldykgvgisvlemshrssdfakii
nntenlvrellavpdnykviflqgggcgqfsavplnliglkagrcadyvvtgawsakaae
eakkfgtinivhpklgsytkipdpstwnlnpdasyvyycanetvhgvefdfipdvkgavl
vcdmssnflskpvdvskfgvifagaqknvgsagvtvvivrddllgfalrecpsvleykvq
agnsslyntppcfsiyvmglvlewiknnggaaameklssiksqtiyeiidnsqgfyvcpv
epqnrskmnipfrignakgddalekrfldkalelnmlslkghrsvggiraslynavtied
vqklaafmkkflemhql

    Sequence, based on observed residues (ATOM records): (download) 
    >3e77B (B:)
enlyfqsmlphsvlleiqkelldykgvgisvlemshrssdfakiinntenlvrellavpd
nykviflqgggcgqfsavplnliglkagrcadyvvtgawsakaaeeakkfgtinivhpkl
gsytkipdpstwnlnpdasyvyycanetvhgvefdfipdvkgavlvcdmssnflskpvdv
skfgvifagaqknvgsagvtvvivrddllgfalrecpsvleykvqagnsslyntppcfsi
yvmglvlewiknnggaaameklssiksqtiyeiidnsqgfyvcpvepqnrskmnipfrig
nakgddalekrfldkalelnmlslkghrsvggiraslynavtiedvqklaafmkkflemh
ql

  • Chain 'C':
    Sequence, based on SEQRES records: (download) 
    >3e77C (C:)
mhhhhhhssgvdlgtenlyfqsmlphsvlleiqkelldykgvgisvlemshrssdfakii
nntenlvrellavpdnykviflqgggcgqfsavplnliglkagrcadyvvtgawsakaae
eakkfgtinivhpklgsytkipdpstwnlnpdasyvyycanetvhgvefdfipdvkgavl
vcdmssnflskpvdvskfgvifagaqknvgsagvtvvivrddllgfalrecpsvleykvq
agnsslyntppcfsiyvmglvlewiknnggaaameklssiksqtiyeiidnsqgfyvcpv
epqnrskmnipfrignakgddalekrfldkalelnmlslkghrsvggiraslynavtied
vqklaafmkkflemhql

    Sequence, based on observed residues (ATOM records): (download) 
    >3e77C (C:)
tenlyfqsmlphsvlleiqkelldykgvgisvlemshrssdfakiinntenlvrellavp
dnykviflqgggcgqfsavplnliglkagrcadyvvtgawsakaaeeakkfgtinivhpk
lgsytkipdpstwnlnpdasyvyycanetvhgvefdfipdvkgavlvcdmssnflskpvd
vskfgvifagaqknvgsagvtvvivrddllgfalrecpsvleykvqagnsslyntppcfs
iyvmglvlewiknnggaaameklssiksqtiyeiidnsqgfyvcpvepqnrskmnipfri
gnakgddalekrfldkalelnmlslkghrsvggiraslynavtiedvqklaafmkkflem
hq