PDB entry 3e6n

View 3e6n on RCSB PDB site
Description: Structure of murine INOS oxygenase domain with inhibitor AR-C125813
Class: oxidoreductase
Keywords: NITRIC OXIDe, NOS, HEME, tetrahydrobiopterin, oxidoreductase, Calmodulin-binding, FAD, FMN, Iron, Metal-binding, NADP, Polymorphism, Zinc
Deposited on 2008-08-15, released 2008-10-07
The last revision prior to the SCOPe 2.04 freeze date was dated 2009-01-20, with a file datestamp of 2009-03-01.
Experiment type: XRAY
Resolution: 2.4 Å
R-factor: 0.233
AEROSPACI score: 0.32 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: Nitric oxide synthase, inducible
    Species: Mus musculus [TaxId:10090]
    Gene: Nos2, Inosl
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.04: d3e6na_
  • Chain 'B':
    Compound: Nitric oxide synthase, inducible
    Species: Mus musculus [TaxId:10090]
    Gene: Nos2, Inosl
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.04: d3e6nb_
  • Heterogens: HEM, H4B, AS3, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download) 
    >3e6nA (A:)
ldklhvtstrpqyvriknwgsgeilhdtlhhkatsdftcksksclgsimnpksltrgprd
kptpleellphaiefinqyygsfkeakieehlarleavtkeiettgtyqltldelifatk
mawrnaprcigriqwsnlqvfdarncstaqemfqhicrhilyatnngnirsaitvfpqrs
dgkhdfrlwnsqliryagyqmpdgtirgdaatleftqlcidlgwkprygrfdvlplvlqa
dgqdpevfeippdlvlevtmehpkyewfqelglkwyalpavanmllevgglefpacpfng
wymgteigvrdfcdtqrynileevgrrmglethtlaslwkdravteinvavlhsfqkqnv
timdhhtasesfmkhmqneyrarggcpadwiwlvppvsgsitpvfhqemlnyvlspfyyy
qiepwkthiwqne

    Sequence, based on observed residues (ATOM records): (download) 
    >3e6nA (A:)
qyvriknwgsgeilhdtlhhkatsclgsimnpksltrgprdkptpleellphaiefinqy
ygsfkeakieehlarleavtkeiettgtyqltldelifatkmawrnaprcigriqwsnlq
vfdarncstaqemfqhicrhilyatnngnirsaitvfpqrsdgkhdfrlwnsqliryagy
qmpdgtirgdaatleftqlcidlgwkprygrfdvlplvlqadgqdpevfeippdlvlevt
mehpkyewfqelglkwyalpavanmllevgglefpacpfngwymgteigvrdfcdtqryn
ileevgrrmglethtlaslwkdravteinvavlhsfqkqnvtimdhhtasesfmkhmqne
yrarggcpadwiwlvppvsgsitpvfhqemlnyvlspfyyyqiepwkthiwqn

  • Chain 'B':
    Sequence, based on SEQRES records: (download) 
    >3e6nB (B:)
ldklhvtstrpqyvriknwgsgeilhdtlhhkatsdftcksksclgsimnpksltrgprd
kptpleellphaiefinqyygsfkeakieehlarleavtkeiettgtyqltldelifatk
mawrnaprcigriqwsnlqvfdarncstaqemfqhicrhilyatnngnirsaitvfpqrs
dgkhdfrlwnsqliryagyqmpdgtirgdaatleftqlcidlgwkprygrfdvlplvlqa
dgqdpevfeippdlvlevtmehpkyewfqelglkwyalpavanmllevgglefpacpfng
wymgteigvrdfcdtqrynileevgrrmglethtlaslwkdravteinvavlhsfqkqnv
timdhhtasesfmkhmqneyrarggcpadwiwlvppvsgsitpvfhqemlnyvlspfyyy
qiepwkthiwqne

    Sequence, based on observed residues (ATOM records): (download) 
    >3e6nB (B:)
qyvriknwgsgeilhdtlhhkatsclgsimnpksltrgprdkptpleellphaiefinqy
ygsfkeakieehlarleavtkeiettgtyqltldelifatkmawrnaprcigriqwsnlq
vfdarncstaqemfqhicrhilyatnngnirsaitvfpqrsdgkhdfrlwnsqliryagy
qmpdgtirgdaatleftqlcidlgwkprygrfdvlplvlqadgqdpevfeippdlvlevt
mehpkyewfqelglkwyalpavanmllevgglefpacpfngwymgteigvrdfcdtqryn
ileevgrrmglethtlaslwkdravteinvavlhsfqkqnvtimdhhtasesfmkhmqne
yrarggcpadwiwlvppvsgsitpvfhqemlnyvlspfyyyqiepwkthiwqn