PDB entry 3e68

View 3e68 on RCSB PDB site
Description: Structure of murine INOS oxygenase domain with inhibitor AR-C130232
Class: oxidoreductase
Keywords: nitric oxide, NOS, HEME, tetrahydrobiopterin, oxidoreductase, Calmodulin-binding, FAD, FMN, Iron, Metal-binding, NADP, Polymorphism, Zinc
Deposited on 2008-08-14, released 2008-10-07
The last revision prior to the SCOPe 2.01 freeze date was dated 2009-01-20, with a file datestamp of 2009-03-01.
Experiment type: XRAY
Resolution: 2.2 Å
R-factor: 0.247
AEROSPACI score: 0.32 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: Nitric oxide synthase, inducible
    Species: Mus musculus [TaxId:10090]
    Gene: Nos2, Inosl
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.01: d3e68a_
  • Chain 'B':
    Compound: Nitric oxide synthase, inducible
    Species: Mus musculus [TaxId:10090]
    Gene: Nos2, Inosl
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.01: d3e68b_
  • Heterogens: BOG, SO4, AT6, HEM, H4B, EDO, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download) 
    >3e68A (A:)
ldklhvtstrpqyvriknwgsgeilhdtlhhkatsdftcksksclgsimnpksltrgprd
kptpleellphaiefinqyygsfkeakieehlarleavtkeiettgtyqltldelifatk
mawrnaprcigriqwsnlqvfdarncstaqemfqhicrhilyatnngnirsaitvfpqrs
dgkhdfrlwnsqliryagyqmpdgtirgdaatleftqlcidlgwkprygrfdvlplvlqa
dgqdpevfeippdlvlevtmehpkyewfqelglkwyalpavanmllevgglefpacpfng
wymgteigvrdfcdtqrynileevgrrmglethtlaslwkdravteinvavlhsfqkqnv
timdhhtasesfmkhmqneyrarggcpadwiwlvppvsgsitpvfhqemlnyvlspfyyy
qiepwkthiwqne

    Sequence, based on observed residues (ATOM records): (download) 
    >3e68A (A:)
qyvriknwgsgeilhdtlhhkatsdftsclgsimnpksltrgprdkptpleellphaief
inqyygsfkeakieehlarleavtkeiettgtyqltldelifatkmawrnaprcigriqw
snlqvfdarncstaqemfqhicrhilyatnngnirsaitvfpqrsdgkhdfrlwnsqlir
yagyqmpdgtirgdaatleftqlcidlgwkprygrfdvlplvlqadgqdpevfeippdlv
levtmehpkyewfqelglkwyalpavanmllevgglefpacpfngwymgteigvrdfcdt
qrynileevgrrmglethtlaslwkdravteinvavlhsfqkqnvtimdhhtasesfmkh
mqneyrarggcpadwiwlvppvsgsitpvfhqemlnyvlspfyyyqiepwkthiw

  • Chain 'B':
    Sequence, based on SEQRES records: (download) 
    >3e68B (B:)
ldklhvtstrpqyvriknwgsgeilhdtlhhkatsdftcksksclgsimnpksltrgprd
kptpleellphaiefinqyygsfkeakieehlarleavtkeiettgtyqltldelifatk
mawrnaprcigriqwsnlqvfdarncstaqemfqhicrhilyatnngnirsaitvfpqrs
dgkhdfrlwnsqliryagyqmpdgtirgdaatleftqlcidlgwkprygrfdvlplvlqa
dgqdpevfeippdlvlevtmehpkyewfqelglkwyalpavanmllevgglefpacpfng
wymgteigvrdfcdtqrynileevgrrmglethtlaslwkdravteinvavlhsfqkqnv
timdhhtasesfmkhmqneyrarggcpadwiwlvppvsgsitpvfhqemlnyvlspfyyy
qiepwkthiwqne

    Sequence, based on observed residues (ATOM records): (download) 
    >3e68B (B:)
qyvriknwgsgeilhdtlhhkatclgsimnpksltrgprdkptpleellphaiefinqyy
gsfkeakieehlarleavtkeiettgtyqltldelifatkmawrnaprcigriqwsnlqv
fdarncstaqemfqhicrhilyatnngnirsaitvfpqrsdgkhdfrlwnsqliryagyq
mpdgtirgdaatleftqlcidlgwkprygrfdvlplvlqadgqdpevfeippdlvlevtm
ehpkyewfqelglkwyalpavanmllevgglefpacpfngwymgteigvrdfcdtqryni
leevgrrmglethtlaslwkdravteinvavlhsfqkqnvtimdhhtasesfmkhmqney
rarggcpadwiwlvppvsgsitpvfhqemlnyvlspfyyyqiepwkthiw