PDB entry 3e4c

View 3e4c on RCSB PDB site
Description: procaspase-1 zymogen domain crystal structure
Deposited on 2008-08-11, released 2008-12-30
The last revision was dated 2021-10-20, with a file datestamp of 2021-10-15.
Experiment type: XRAY
Resolution: 2.05 Å
R-factor: N/A
AEROSPACI score: 0.33 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: Caspase-1
    Species: Homo sapiens [TaxId:9606]
    Gene: CASP1, IL1BC, IL1BCE
    Database cross-references and differences (RAF-indexed):
    • Uniprot P29466 (1-301)
      • expression tag (0)
      • engineered mutation (182)
  • Chain 'B':
    Compound: Caspase-1
    Species: Homo sapiens [TaxId:9606]
    Gene: CASP1, IL1BC, IL1BCE
    Database cross-references and differences (RAF-indexed):
    • Uniprot P29466 (1-301)
      • expression tag (0)
      • engineered mutation (182)
  • Heterogens: MG, HOH

PDB Chain Sequences:
This PDB entry is not classified in SCOPe 2.08, so the chain sequences below are not included in the ASTRAL sequence sets.

  • Chain 'A':
    Sequence, based on SEQRES records:
    >3e4cA (A:)
qsqgvlssfpapqavqdnpamptssgsegnvklcsleeaqriwkqksaeiypimdkssrt
rlaliicneefdsiprrtgaevditgmtmllqnlgysvdvkknltasdmtteleafahrp
ehktsdstflvfmshgiregicgkkhseqvpdilqlnaifnmlntkncpslkdkpkviii
qaargdspgvvwfkdsvgvsgnlslptteefeddaikkahiekdfiafcsstpdnvswrh
ptmgsvfigrliehmqeyacscdveeifrkvrfsfeqpdgraqmpttervtltrcfylfp
gh

    Sequence, based on observed residues (ATOM records):
    >3e4cA (A:)
ssgsegnvklcsleeaqriwkqksaeiypimdkssrtrlaliicneefdsiprrtgaevd
itgmtmllqnlgysvdvkknltasdmtteleafahrpehktsdstflvfmshgiregicg
kkhseqvpdilqlnaifnmlntkncpslkdkpkviiiqaargdspgvvwfkdslptteef
eddaikkahiekdfiafcsstpdnvswrhptmgsvfigrliehmqeyacscdveeifrkv
rfsfeqpdgraqmpttervtltrcfylfpgh

  • Chain 'B':
    Sequence, based on SEQRES records:
    >3e4cB (B:)
qsqgvlssfpapqavqdnpamptssgsegnvklcsleeaqriwkqksaeiypimdkssrt
rlaliicneefdsiprrtgaevditgmtmllqnlgysvdvkknltasdmtteleafahrp
ehktsdstflvfmshgiregicgkkhseqvpdilqlnaifnmlntkncpslkdkpkviii
qaargdspgvvwfkdsvgvsgnlslptteefeddaikkahiekdfiafcsstpdnvswrh
ptmgsvfigrliehmqeyacscdveeifrkvrfsfeqpdgraqmpttervtltrcfylfp
gh

    Sequence, based on observed residues (ATOM records):
    >3e4cB (B:)
gsegnvklcsleeaqriwkqksaeiypimdkssrtrlaliicneefdsiprrtgaevdit
gmtmllqnlgysvdvkknltasdmtteleafahrpehktsdstflvfmshgiregicgkk
hseqvpdilqlnaifnmlntkncpslkdkpkviiiqaargdspgvvwfkdslptteefed
daikkahiekdfiafcsstpdnvswrhptmgsvfigrliehmqeyacscdveeifrkvrf
sfeqpdgraqmpttervtltrcfylfpgh