PDB entry 3e2u

View 3e2u on RCSB PDB site
Description: Crystal structure of the zink-knuckle 2 domain of human CLIP-170 in complex with CAP-Gly domain of human dynactin-1 (p150-GLUED)
Class: protein binding
Keywords: STRUCTURAL PROTEIN MICROTUBULE BINDING, DYNACTIN, CYTOSKELETON ASSOCIATED PROTEIN, P150GLUED, CLIP-170/RESTIN, +TIP PROTEIN COMPLEX STRUCTURE, ZINC-KNUCKLE, AUTOINHIBITION, PROTEIN BINDING, Cytoskeleton, Dynein, Microtubule, Motor protein, Phosphoprotein
Deposited on 2008-08-06, released 2008-08-19
The last revision prior to the SCOPe 2.05 freeze date was dated 2011-07-13, with a file datestamp of 2011-05-08.
Experiment type: XRAY
Resolution: 2.6 Å
R-factor: 0.193
AEROSPACI score: 0.28 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: Dynactin subunit 1
    Species: Homo sapiens [TaxId:9606]
    Gene: DCTN1
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.05: d3e2ua_
  • Chain 'B':
    Compound: Dynactin subunit 1
    Species: Homo sapiens [TaxId:9606]
    Gene: DCTN1
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.05: d3e2ub_
  • Chain 'C':
    Compound: Dynactin subunit 1
    Species: Homo sapiens [TaxId:9606]
    Gene: DCTN1
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.05: d3e2uc_
  • Chain 'D':
    Compound: Dynactin subunit 1
    Species: Homo sapiens [TaxId:9606]
    Gene: DCTN1
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.05: d3e2ud_
  • Chain 'E':
    Compound: CAP-Gly domain-containing linker protein 1
    Species: Homo sapiens [TaxId:9606]
    Gene: CLIP1, CYLN1, RSN
    Database cross-references and differences (RAF-indexed):
  • Chain 'F':
    Compound: CAP-Gly domain-containing linker protein 1
    Species: Homo sapiens [TaxId:9606]
    Gene: CLIP1, CYLN1, RSN
    Database cross-references and differences (RAF-indexed):
  • Chain 'G':
    Compound: CAP-Gly domain-containing linker protein 1
    Species: Homo sapiens [TaxId:9606]
    Gene: CLIP1, CYLN1, RSN
    Database cross-references and differences (RAF-indexed):
  • Chain 'H':
    Compound: CAP-Gly domain-containing linker protein 1
    Species: Homo sapiens [TaxId:9606]
    Gene: CLIP1, CYLN1, RSN
    Database cross-references and differences (RAF-indexed):
  • Heterogens: ZN, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download) 
    >3e2uA (A:)
gshmsaeasarplrvgsrvevigkghrgtvayvgatlfatgkwvgvildeakgkndgtvq
grkyftcdeghgifvrqsqiqvfedgadttspetpds

    Sequence, based on observed residues (ATOM records): (download) 
    >3e2uA (A:)
lrvgsrvevigkghrgtvayvgatlfatgkwvgvildeakgkndgtvqgrkyftcdeghg
ifvrqsqiqvf

  • Chain 'B':
    Sequence, based on SEQRES records: (download) 
    >3e2uB (B:)
gshmsaeasarplrvgsrvevigkghrgtvayvgatlfatgkwvgvildeakgkndgtvq
grkyftcdeghgifvrqsqiqvfedgadttspetpds

    Sequence, based on observed residues (ATOM records): (download) 
    >3e2uB (B:)
plrvgsrvevigkghrgtvayvgatlfatgkwvgvildeakgkndgtvqgrkyftcdegh
gifvrqsqiqvf

  • Chain 'C':
    Sequence, based on SEQRES records: (download) 
    >3e2uC (C:)
gshmsaeasarplrvgsrvevigkghrgtvayvgatlfatgkwvgvildeakgkndgtvq
grkyftcdeghgifvrqsqiqvfedgadttspetpds

    Sequence, based on observed residues (ATOM records): (download) 
    >3e2uC (C:)
plrvgsrvevigkghrgtvayvgatlfatgkwvgvildeakgkndgtvqgrkyftcdegh
gifvrqsqiqvf

  • Chain 'D':
    Sequence, based on SEQRES records: (download) 
    >3e2uD (D:)
gshmsaeasarplrvgsrvevigkghrgtvayvgatlfatgkwvgvildeakgkndgtvq
grkyftcdeghgifvrqsqiqvfedgadttspetpds

    Sequence, based on observed residues (ATOM records): (download) 
    >3e2uD (D:)
plrvgsrvevigkghrgtvayvgatlfatgkwvgvildeakgkndgtvqgrkyftcdegh
gifvrqsqiqvfed

  • Chain 'E':
    No sequence available.

  • Chain 'F':
    No sequence available.

  • Chain 'G':
    No sequence available.

  • Chain 'H':
    No sequence available.