PDB entry 3e1y

View 3e1y on RCSB PDB site
Description: Crystal structure of human eRF1/eRF3 complex
Deposited on 2008-08-05, released 2009-05-19
The last revision was dated 2011-07-13, with a file datestamp of 2011-05-08.
Experiment type: XRAY
Resolution: 3.8 Å
R-factor: 0.262
AEROSPACI score: 0.04 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: Eukaryotic peptide chain release factor subunit 1
    Species: Homo sapiens [TaxId:9606]
    Gene: ETF1, ERF1, RF1, SUP45L1
    Database cross-references and differences (RAF-indexed):
  • Chain 'B':
    Compound: Eukaryotic peptide chain release factor subunit 1
    Species: Homo sapiens [TaxId:9606]
    Gene: ETF1, ERF1, RF1, SUP45L1
    Database cross-references and differences (RAF-indexed):
  • Chain 'C':
    Compound: Eukaryotic peptide chain release factor subunit 1
    Species: Homo sapiens [TaxId:9606]
    Gene: ETF1, ERF1, RF1, SUP45L1
    Database cross-references and differences (RAF-indexed):
  • Chain 'D':
    Compound: Eukaryotic peptide chain release factor subunit 1
    Species: Homo sapiens [TaxId:9606]
    Gene: ETF1, ERF1, RF1, SUP45L1
    Database cross-references and differences (RAF-indexed):
  • Chain 'E':
    Compound: Eukaryotic peptide chain release factor GTP-binding subunit ERF3A
    Species: Homo sapiens [TaxId:9606]
    Gene: GSPT1, ERF3A
    Database cross-references and differences (RAF-indexed):
  • Chain 'F':
    Compound: Eukaryotic peptide chain release factor GTP-binding subunit ERF3A
    Species: Homo sapiens [TaxId:9606]
    Gene: GSPT1, ERF3A
    Database cross-references and differences (RAF-indexed):
  • Chain 'G':
    Compound: Eukaryotic peptide chain release factor GTP-binding subunit ERF3A
    Species: Homo sapiens [TaxId:9606]
    Gene: GSPT1, ERF3A
    Database cross-references and differences (RAF-indexed):
  • Chain 'H':
    Compound: Eukaryotic peptide chain release factor GTP-binding subunit ERF3A
    Species: Homo sapiens [TaxId:9606]
    Gene: GSPT1, ERF3A
    Database cross-references and differences (RAF-indexed):
  • Heterogens: ATP

PDB Chain Sequences:
This PDB entry is not classified in SCOPe 2.08, so the chain sequences below are not included in the ASTRAL sequence sets.

  • Chain 'A':
    Sequence, based on SEQRES records:
    >3e1yA (A:)
mrgshhhhhhgmasmaddpsaadrnveiwkikkliksleaargngtsmisliippkdqis
rvakmladefgtasniksrvnrlsvlgaitsvqqrlklynkvppnglvvycgtivteegk
ekkvnidfepfkpintslylcdnkfhtealtallsddskfgfividgsgalfgtlqgntr
evlhkftvdlpkkhgrggqsalrfarlrmekrhnyvrkvaetavqlfisgdkvnvaglvl
agsadfktelsqsdmfdqrlqskvlklvdisyggengfnqaielstevlsnvkfiqekkl
igryfdeisqdtgkycfgvedtlkalemgaveilivyenldimryvlhcqgteeekilyl
tpeqekdkshftdketgqeheliesmpllewfannykkfgatleivtdksqegsqfvkgf
ggiggilryrvdfqgmeyqggddeffdlddy

    Sequence, based on observed residues (ATOM records):
    >3e1yA (A:)
aadrnveiwkikkliksleaargngtsmisliippkdqisrvakmladefgtasniksrv
nrlsvlgaitsvqqrlklynkvppnglvvycgtivteegkekkvnidfepfkpintslyl
cdnkfhtealtallsddskfgfividgsgalfgtlqgntrevlhkftvdlpkkhgrggqs
alrfarlrmekrhnyvrkvaetavqlfisgdkvnvaglvlagsadfktelsqsdmfdqrl
qskvlklvdisyggengfnqaielstevlsnvkfiqekkligryfdeisqdtgkycfgve
dtlkalemgaveilivyenldimrlyltpeqmpllewfannykkfgatleivtdksqegs
qfvkgfggiggilryrvdfq

  • Chain 'B':
    Sequence, based on SEQRES records:
    >3e1yB (B:)
mrgshhhhhhgmasmaddpsaadrnveiwkikkliksleaargngtsmisliippkdqis
rvakmladefgtasniksrvnrlsvlgaitsvqqrlklynkvppnglvvycgtivteegk
ekkvnidfepfkpintslylcdnkfhtealtallsddskfgfividgsgalfgtlqgntr
evlhkftvdlpkkhgrggqsalrfarlrmekrhnyvrkvaetavqlfisgdkvnvaglvl
agsadfktelsqsdmfdqrlqskvlklvdisyggengfnqaielstevlsnvkfiqekkl
igryfdeisqdtgkycfgvedtlkalemgaveilivyenldimryvlhcqgteeekilyl
tpeqekdkshftdketgqeheliesmpllewfannykkfgatleivtdksqegsqfvkgf
ggiggilryrvdfqgmeyqggddeffdlddy

    Sequence, based on observed residues (ATOM records):
    >3e1yB (B:)
aadrnveiwkikkliksleaargngtsmisliippkdqisrvakmladefgtasniksrv
nrlsvlgaitsvqqrlklynkvppnglvvycgtivteegkekkvnidfepfkpintslyl
cdnkfhtealtallsddskfgfividgsgalfgtlqgntrevlhkftvdlpkkhgrggqs
alrfarlrmekrhnyvrkvaetavqlfisgdkvnvaglvlagsadfktelsqsdmfdqrl
qskvlklvdisyggengfnqaielstevlsnvkfiqekkligryfdeisqdtgkycfgve
dtlkalemgaveilivyenldimrlyltpeqmpllewfannykkfgatleivtdksqegs
qfvkgfggiggilryrvdfq

  • Chain 'C':
    Sequence, based on SEQRES records:
    >3e1yC (C:)
mrgshhhhhhgmasmaddpsaadrnveiwkikkliksleaargngtsmisliippkdqis
rvakmladefgtasniksrvnrlsvlgaitsvqqrlklynkvppnglvvycgtivteegk
ekkvnidfepfkpintslylcdnkfhtealtallsddskfgfividgsgalfgtlqgntr
evlhkftvdlpkkhgrggqsalrfarlrmekrhnyvrkvaetavqlfisgdkvnvaglvl
agsadfktelsqsdmfdqrlqskvlklvdisyggengfnqaielstevlsnvkfiqekkl
igryfdeisqdtgkycfgvedtlkalemgaveilivyenldimryvlhcqgteeekilyl
tpeqekdkshftdketgqeheliesmpllewfannykkfgatleivtdksqegsqfvkgf
ggiggilryrvdfqgmeyqggddeffdlddy

    Sequence, based on observed residues (ATOM records):
    >3e1yC (C:)
aadrnveiwkikkliksleasmisliippsrvakmladefgtrvnrlsvlgaitsvqqrl
kllvvycidfepfkpintslylcfhtealtallsddskfgfividgsgalfgtlqgntre
vlhkftmekrhnyvrkvaetavqlfisgdkvnvaglvlagsadfktelsqsdmfdqrlqs
kvlklvdisyggengfnqaielstevlsnvkfiqekkligryfdeisqdtgkycfgvedt
lkalemgaveilivyenldimrylyltpeqsmpllewfannykkfgatleivtdksqegs
qfvkgfggiggilryrvd

  • Chain 'D':
    Sequence, based on SEQRES records:
    >3e1yD (D:)
mrgshhhhhhgmasmaddpsaadrnveiwkikkliksleaargngtsmisliippkdqis
rvakmladefgtasniksrvnrlsvlgaitsvqqrlklynkvppnglvvycgtivteegk
ekkvnidfepfkpintslylcdnkfhtealtallsddskfgfividgsgalfgtlqgntr
evlhkftvdlpkkhgrggqsalrfarlrmekrhnyvrkvaetavqlfisgdkvnvaglvl
agsadfktelsqsdmfdqrlqskvlklvdisyggengfnqaielstevlsnvkfiqekkl
igryfdeisqdtgkycfgvedtlkalemgaveilivyenldimryvlhcqgteeekilyl
tpeqekdkshftdketgqeheliesmpllewfannykkfgatleivtdksqegsqfvkgf
ggiggilryrvdfqgmeyqggddeffdlddy

    Sequence, based on observed residues (ATOM records):
    >3e1yD (D:)
aadrnveiwkikkliksleasmisliippsrvakmladefgtrvnrlsvlgaitsvqqrl
kllvvycidfepfkpintslylcfhtealtallsddskfgfividgsgalfgtlqgntre
vlhkftmekrhnyvrkvaetavqlfisgdkvnvaglvlagsadfktelsqsdmfdqrlqs
kvlklvdisyggengfnqaielstevlsnvkfiqekkligryfdeisqdtgkycfgvedt
lkalemgaveilivyenldimrylyltpeqsmpllewfannykkfgatleivtdksqegs
qfvkgfggiggilryrvd

  • Chain 'E':
    Sequence, based on SEQRES records:
    >3e1yE (E:)
gplgspirlpivdkykdmgtvvlgklesgsickgqqlvmmpnkhnvevlgilsddvetdt
vapgenlkirlkgieeeeilpgfilcdpnnlchsgrtfdaqiviiehksiicpgynavlh
ihtcieeveitaliclvdkksgeksktrprfvkqdqvciarlrtagticletfkdfpqmg
rftlrdegktiaigkvlklvpekd

    Sequence, based on observed residues (ATOM records):
    >3e1yE (E:)
irlpivdkykdmgtvvlgklesgsickgqqlvmmpnkhnvevlgilsddvetdtvapgen
lkirlkgieeeeilpgfilcdpnnlchsgrtfdaqiviiehksiicpgynavlhihtcie
eveitaliclvdkksgeksktrprfvkqdqvciarlrtagticletfkdfpqmgrftlrd
egktiaigkvlklvp

  • Chain 'F':
    Sequence, based on SEQRES records:
    >3e1yF (F:)
gplgspirlpivdkykdmgtvvlgklesgsickgqqlvmmpnkhnvevlgilsddvetdt
vapgenlkirlkgieeeeilpgfilcdpnnlchsgrtfdaqiviiehksiicpgynavlh
ihtcieeveitaliclvdkksgeksktrprfvkqdqvciarlrtagticletfkdfpqmg
rftlrdegktiaigkvlklvpekd

    Sequence, based on observed residues (ATOM records):
    >3e1yF (F:)
irlpivdkykdmgtvvlgklesgsickgqqlvmmpnkhnvevlgilsddvetdtvapgen
lkirlkgieeeeilpgfilcdpnnlchsgrtfdaqiviiehksiicpgynavlhihtcie
eveitaliclvdkksgeksktrprfvkqdqvciarlrtagticletfkdfpqmgrftlrd
egktiaigkvlklvp

  • Chain 'G':
    Sequence, based on SEQRES records:
    >3e1yG (G:)
gplgspirlpivdkykdmgtvvlgklesgsickgqqlvmmpnkhnvevlgilsddvetdt
vapgenlkirlkgieeeeilpgfilcdpnnlchsgrtfdaqiviiehksiicpgynavlh
ihtcieeveitaliclvdkksgeksktrprfvkqdqvciarlrtagticletfkdfpqmg
rftlrdegktiaigkvlklvpekd

    Sequence, based on observed residues (ATOM records):
    >3e1yG (G:)
irlpivdkykdmgtvvlgklesgsickgqqlvmmpnkhnvevlgilsddvetdtvapgen
lkirlkgieeeeilpgfilcdpnnlchsgrtfdaqiviiehksiicpgynavlhihtcie
eveitaliclvdkksgeksktrprfvkqdqvciarlrtagticletfkdfpqmgrftlrd
egktiaigkvlklvp

  • Chain 'H':
    Sequence, based on SEQRES records:
    >3e1yH (H:)
gplgspirlpivdkykdmgtvvlgklesgsickgqqlvmmpnkhnvevlgilsddvetdt
vapgenlkirlkgieeeeilpgfilcdpnnlchsgrtfdaqiviiehksiicpgynavlh
ihtcieeveitaliclvdkksgeksktrprfvkqdqvciarlrtagticletfkdfpqmg
rftlrdegktiaigkvlklvpekd

    Sequence, based on observed residues (ATOM records):
    >3e1yH (H:)
irlpivdkykdmgtvvlgklesgsickgqqlvmmpnkhnvevlgilsddvetdtvapgen
lkirlkgieeeeilpgfilcdpnnlchsgrtfdaqiviiehksiicpgynavlhihtcie
eveitaliclvdkksgeksktrprfvkqdqvciarlrtagticletfkdfpqmgrftlrd
egktiaigkvlklvp