PDB entry 3e0d

View 3e0d on RCSB PDB site
Description: insights into the replisome from the crystral structure of the ternary complex of the eubacterial dna polymerase iii alpha-subunit
Deposited on 2008-07-31, released 2008-09-23
The last revision was dated 2021-10-20, with a file datestamp of 2021-10-15.
Experiment type: XRAY
Resolution: 4.6 Å
R-factor: 0.287
AEROSPACI score: 0.04 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: DNA polymerase III subunit alpha
    Species: Thermus aquaticus [TaxId:271]
    Gene: dnaE
    Database cross-references and differences (RAF-indexed):
    • Uniprot Q9XDH5 (0-1219)
      • engineered mutation (19)
      • engineered mutation (211)
      • engineered mutation (538-541)
  • Chain 'B':
    Compound: DNA polymerase III subunit alpha
    Species: Thermus aquaticus [TaxId:271]
    Gene: dnaE
    Database cross-references and differences (RAF-indexed):
    • Uniprot Q9XDH5 (0-1219)
      • engineered mutation (19)
      • engineered mutation (211)
      • engineered mutation (538-541)
  • Chain 'C':
    Compound: DNA substrate template strand
  • Chain 'D':
    Compound: DNA substrate primer strand
  • Chain 'E':
    Compound: DNA substrate template strand
  • Chain 'F':
    Compound: DNA substrate primer strand
  • Heterogens: CA, DTP

PDB Chain Sequences:
This PDB entry is not classified in SCOPe 2.08, so the chain sequences below are not included in the ASTRAL sequence sets.

  • Chain 'A':
    Sequence, based on SEQRES records:
    >3e0dA (A:)
mgsklkfahlhqhtqfsllngaaklqdllkwvkettpedpalamtdhgnlfgavefykka
tamgvkpiigyeayvaaesrfdrkrgkgldggyfhltllakdftgyqnlvrlasrayleg
fyekpridreilrehaqglialsgclgaeipqfilqdrldlaearlnedlsifgdrffie
iqnhglpeqkkvnqvlkefarkyglgmvatnnghyvrkedarahevllaiqskttlddpe
rwrfpcdefyvktpeemramlpeaewgdepfdntveiarmcdvdlpigdkmvyriprfpl
pegrteaqylreltflgllrrypdriteafyrevlrllgtmpphgderalaealarveek
aweelrkrlpplegvrewtaeailhralyelsviermgfpgyflivqdyinwarghgvsv
gpgrgsaagslvayavgitnidplrfgllferflnpervsmpdidtdfsdrerdrviqyv
rerygedkvaqigtfgslaskaalkdvarvygiphkkaeelaklipvqfgkpkplqeafe
aepelraemekderirqvievamrleglnrhasvhaagvviaaepltdlvplmrdqegrp
vtqydmgavealgllkmdflglrtltfldearrivkeskgveldydrlplddpktfells
rgetkgvfqlesggmtatvrglkprrlediialvslyrpgpmehiptyirrhhgqepvsy
aefphaekylrpildetygipvyqeqimqiasqvagyslgeadllrramgkkrveemqkh
rerfvrgakergvpeeeanrlfdmleafanygfnkshaaaysllsyqtayvkahypvefm
aallsverhdsdkvaeyirdaralgipvlppdvnrsgfdfkvvgeeilfglsavknvgem
aaraileererggpfkslgdflkrlpeqvvnkraleslvkagaldafgdrarllaslepl
lrwaaetrergrsglvglfaeveepplveaspldeitmlryekealgiyvsghpvlrypg
lrevasctieelsefvrelpgkpkvllsgmveevvrkptrsggmmarftlsdetgalevv
vfgrayegvspklkedipllvlaevekgeelrvlaqavwtleevleapkalevevdhall
dekgvarlkslldehpgslpvylrvlgpfgealfalrevrvgeealglleaegyraylvp
drevflqgngggpkeevvpf

    Sequence, based on observed residues (ATOM records):
    >3e0dA (A:)
lkfahlhqhtqfsllngaaklqdllkwvkettpedpalamtdhgnlfgavefykkatamg
vkpiigyeayvaaesrfdrkrggyfhltllakdftgyqnlvrlasraylegfyekpridr
eilrehaqglialsgclgaeipqfilqdrldlaearlnedlsifgdrffieiqnhglpeq
kkvnqvlkefarkyglgmvatnnghyvrkedarahevllaiqskttlddperwrfpcdef
yvktpeemramlpeaewgdepfdntveiarmcdvdlpigdkmvyriprfplgrteaqylr
eltflgllrrypdriteafyrevlrllderalaealarveekaweelrkrewtaeailhr
alyelsviermgfpgyflivqdyinwarghgvsvgpgrgsaagslvayavgitnidplrf
gllferflnpervsmpdidtdfsdrerdrviqyvrerygedkvaqigtfgslaskaalkd
varvygiphkkaeelaklipvqfgkpkplqeafeaepelraemekderirqvievamrle
glnrhasvhaagvviaaepltdlvplmrdqegrpvtqydmgavealgllkmdflglrtlt
fldearrivkeskgveldydrlplddpktfellsrgetkgvfqlesggmtatvrglkprr
lediialvslyrpgpmehiptyirrhhgqepvsyaefphaekylrpildetygipvyqeq
imqiasqvagyslgeadllrramgkkrveemqkhrerfvrgakergvpeeeanrlfdmle
afanygfnkshaaaysllsyqtayvkahypvefmaallsverhdsdkvaeyirdaralgi
pvlppdvnrsgfdfkvvgeeilfglsavknvgemaaraileererggpfkslgdflkrlp
eqvvnkraleslvkagaldafgdrarllaslepllrwaaetrergrsglvglfaeveepp
lveaspldeitmlryekealgiyvsghpvlrypglrevasctieelsefvrelpgkpkvl
lsgmveevrftlsdetgalevvkedipllvlaevervlaqavwtleevleapkalevevd
halldekgarlkslldehpgslpvylrvlgpfgealfalrevrvgeealglleaegyray
lvpdrevf

  • Chain 'B':
    Sequence, based on SEQRES records:
    >3e0dB (B:)
mgsklkfahlhqhtqfsllngaaklqdllkwvkettpedpalamtdhgnlfgavefykka
tamgvkpiigyeayvaaesrfdrkrgkgldggyfhltllakdftgyqnlvrlasrayleg
fyekpridreilrehaqglialsgclgaeipqfilqdrldlaearlnedlsifgdrffie
iqnhglpeqkkvnqvlkefarkyglgmvatnnghyvrkedarahevllaiqskttlddpe
rwrfpcdefyvktpeemramlpeaewgdepfdntveiarmcdvdlpigdkmvyriprfpl
pegrteaqylreltflgllrrypdriteafyrevlrllgtmpphgderalaealarveek
aweelrkrlpplegvrewtaeailhralyelsviermgfpgyflivqdyinwarghgvsv
gpgrgsaagslvayavgitnidplrfgllferflnpervsmpdidtdfsdrerdrviqyv
rerygedkvaqigtfgslaskaalkdvarvygiphkkaeelaklipvqfgkpkplqeafe
aepelraemekderirqvievamrleglnrhasvhaagvviaaepltdlvplmrdqegrp
vtqydmgavealgllkmdflglrtltfldearrivkeskgveldydrlplddpktfells
rgetkgvfqlesggmtatvrglkprrlediialvslyrpgpmehiptyirrhhgqepvsy
aefphaekylrpildetygipvyqeqimqiasqvagyslgeadllrramgkkrveemqkh
rerfvrgakergvpeeeanrlfdmleafanygfnkshaaaysllsyqtayvkahypvefm
aallsverhdsdkvaeyirdaralgipvlppdvnrsgfdfkvvgeeilfglsavknvgem
aaraileererggpfkslgdflkrlpeqvvnkraleslvkagaldafgdrarllaslepl
lrwaaetrergrsglvglfaeveepplveaspldeitmlryekealgiyvsghpvlrypg
lrevasctieelsefvrelpgkpkvllsgmveevvrkptrsggmmarftlsdetgalevv
vfgrayegvspklkedipllvlaevekgeelrvlaqavwtleevleapkalevevdhall
dekgvarlkslldehpgslpvylrvlgpfgealfalrevrvgeealglleaegyraylvp
drevflqgngggpkeevvpf

    Sequence, based on observed residues (ATOM records):
    >3e0dB (B:)
lkfahlhqhtqfsllngaaklqdllkwvkettpedpalamtdhgnlfgavefykkatamg
vkpiigyeayvaaesrfdrkrggyfhltllakdftgyqnlvrlasraylegfyekpridr
eilrehaqglialsgclgaeipqfilqdrldlaearlnedlsifgdrffieiqnhglpeq
kkvnqvlkefarkyglgmvatnnghyvrkedarahevllaiqskttlddperwrfpcdef
yvktpeemramlpeaewgdepfdntveiarmcdvdlpigdkmvyriprfplgrteaqylr
eltflgllrrypdriteafyrevlrllderalaealarveekaweelrkrewtaeailhr
alyelsviermgfpgyflivqdyinwarghgvsvgpgrgsaagslvayavgitnidplrf
gllferflnpervsmpdidtdfsdrerdrviqyvrerygedkvaqigtfgslaskaalkd
varvygiphkkaeelaklipvqfgkpkplqeafeaepelraemekderirqvievamrle
glnrhasvhaagvviaaepltdlvplmrdqegrpvtqydmgavealgllkmdflglrtlt
fldearrivkeskgveldydrlplddpktfellsrgetkgvfqlesggmtatvrglkprr
lediialvslyrpgpmehiptyirrhhgqepvsyaefphaekylrpildetygipvyqeq
imqiasqvagyslgeadllrramgkkrveemqkhrerfvrgakergvpeeeanrlfdmle
afanygfnkshaaaysllsyqtayvkahypvefmaallsverhdsdkvaeyirdaralgi
pvlppdvnrsgfdfkvvgeeilfglsavknvgemaaraileererggpfkslgdflkrlp
eqvvnkraleslvkagaldafgdrarllaslepllrwaaetrergrsglvglfaeveepp
lveaspldeitmlryekealgiyvsghpvlrypglrevasctieelsefvrelpgkpkvl
lsgmveevrftlsdetgalevvkedipllvlaevervlaqavwtleevleapkalevevd
halldekgarlkslldehpgslpvylrvlgpfgealfalrevrvgeealglleaegyray
lvpdrevf

  • Chain 'C':
    No sequence available.

  • Chain 'D':
    No sequence available.

  • Chain 'E':
    No sequence available.

  • Chain 'F':
    No sequence available.