PDB entry 3e08

View 3e08 on RCSB PDB site
Description: H55S mutant Xanthomonas campestris tryptophan 2,3-dioxygenase
Class: oxidoreductase
Keywords: TDO, heme, tryptophan 2, 3-dioxygenase, H55S, OXIDOREDUCTASE, Dioxygenase
Deposited on 2008-07-31, released 2008-09-30
The last revision prior to the SCOPe 2.08 freeze date was dated 2009-02-24, with a file datestamp of 2009-03-01.
Experiment type: XRAY
Resolution: 1.9 Å
R-factor: 0.178
AEROSPACI score: 0.49 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: Tryptophan 2,3-dioxygenase
    Species: Xanthomonas campestris pv. campestris [TaxId:340]
    Gene: xccb100_0466
    Database cross-references and differences (RAF-indexed):
    • Uniprot Q8PDA8
      • engineered (54)
    Domains in SCOPe 2.08: d3e08a_
  • Chain 'B':
    Compound: Tryptophan 2,3-dioxygenase
    Species: Xanthomonas campestris pv. campestris [TaxId:340]
    Gene: xccb100_0466
    Database cross-references and differences (RAF-indexed):
    • Uniprot Q8PDA8
      • engineered (54)
    Domains in SCOPe 2.08: d3e08b_
  • Chain 'C':
    Compound: Tryptophan 2,3-dioxygenase
    Species: Xanthomonas campestris pv. campestris [TaxId:340]
    Gene: xccb100_0466
    Database cross-references and differences (RAF-indexed):
    • Uniprot Q8PDA8
      • engineered (54)
    Domains in SCOPe 2.08: d3e08c_
  • Chain 'D':
    Compound: Tryptophan 2,3-dioxygenase
    Species: Xanthomonas campestris pv. campestris [TaxId:340]
    Gene: xccb100_0466
    Database cross-references and differences (RAF-indexed):
    • Uniprot Q8PDA8
      • engineered (54)
    Domains in SCOPe 2.08: d3e08d_
  • Chain 'E':
    Compound: Tryptophan 2,3-dioxygenase
    Species: Xanthomonas campestris pv. campestris [TaxId:340]
    Gene: xccb100_0466
    Database cross-references and differences (RAF-indexed):
    • Uniprot Q8PDA8
      • engineered (54)
    Domains in SCOPe 2.08: d3e08e_
  • Chain 'F':
    Compound: Tryptophan 2,3-dioxygenase
    Species: Xanthomonas campestris pv. campestris [TaxId:340]
    Gene: xccb100_0466
    Database cross-references and differences (RAF-indexed):
    • Uniprot Q8PDA8
      • engineered (54)
    Domains in SCOPe 2.08: d3e08f_
  • Chain 'G':
    Compound: Tryptophan 2,3-dioxygenase
    Species: Xanthomonas campestris pv. campestris [TaxId:340]
    Gene: xccb100_0466
    Database cross-references and differences (RAF-indexed):
    • Uniprot Q8PDA8
      • engineered (54)
    Domains in SCOPe 2.08: d3e08g_
  • Chain 'H':
    Compound: Tryptophan 2,3-dioxygenase
    Species: Xanthomonas campestris pv. campestris [TaxId:340]
    Gene: xccb100_0466
    Database cross-references and differences (RAF-indexed):
    • Uniprot Q8PDA8
      • engineered (54)
    Domains in SCOPe 2.08: d3e08h_
  • Heterogens: TRP, HEM, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download) 
    >3e08A (A:)
mpvdknlrdlepgihtdlegrltyggylrldqllsaqqplsepahhdemlfiiqsqtsel
wlkllahelraaivhlqrdevwqcrkvlarskqvlrqlteqwsvletltpseymgfrdvl
gpssgfqslqyryiefllgnknpqmlqvfaydpagqarlrevleapslyeeflrylarfg
haipqqyqardwtaahvaddtlrpvferiyentdrywreyslcedlvdvetqfqlwrfrh
mrtvmrvigfkrgtggssgvgflqqalaltffpelfdvrtsvgvdnrppqgsadagkr

    Sequence, based on observed residues (ATOM records): (download) 
    >3e08A (A:)
lrdlepgihtdlegrltyggylrldqllsaqqplsepahhdemlfiiqsqtselwlklla
helraaivhlqrdevwqcrkvlarskqvlrqlteqwsvletltpseymgfrdvlgpssgf
qslqyryiefllgnknpqmlqvfaydpagqarlrevleapslyeeflrylarfghaipqq
yqardwtaahvaddtlrpvferiyentdrywreyslcedlvdvetqfqlwrfrhmrtvmr
vigfkrgtggssgvgflqqalaltffpelfdvrtsvgvdn

  • Chain 'B':
    Sequence, based on SEQRES records: (download) 
    >3e08B (B:)
mpvdknlrdlepgihtdlegrltyggylrldqllsaqqplsepahhdemlfiiqsqtsel
wlkllahelraaivhlqrdevwqcrkvlarskqvlrqlteqwsvletltpseymgfrdvl
gpssgfqslqyryiefllgnknpqmlqvfaydpagqarlrevleapslyeeflrylarfg
haipqqyqardwtaahvaddtlrpvferiyentdrywreyslcedlvdvetqfqlwrfrh
mrtvmrvigfkrgtggssgvgflqqalaltffpelfdvrtsvgvdnrppqgsadagkr

    Sequence, based on observed residues (ATOM records): (download) 
    >3e08B (B:)
lrdlepgihtdlegrltyggylrldqllsaqqplsepahhdemlfiiqsqtselwlklla
helraaivhlqrdevwqcrkvlarskqvlrqlteqwsvletltpseymgfrdvlgpssgf
qslqyryiefllgnknpqmlqvfaydpagqarlrevleapslyeeflrylarfghaipqq
yqardwtaahvaddtlrpvferiyentdrywreyslcedlvdvetqfqlwrfrhmrtvmr
vigfkrgtggssgvgflqqalaltffpelfdvrtsvgvdn

  • Chain 'C':
    Sequence, based on SEQRES records: (download) 
    >3e08C (C:)
mpvdknlrdlepgihtdlegrltyggylrldqllsaqqplsepahhdemlfiiqsqtsel
wlkllahelraaivhlqrdevwqcrkvlarskqvlrqlteqwsvletltpseymgfrdvl
gpssgfqslqyryiefllgnknpqmlqvfaydpagqarlrevleapslyeeflrylarfg
haipqqyqardwtaahvaddtlrpvferiyentdrywreyslcedlvdvetqfqlwrfrh
mrtvmrvigfkrgtggssgvgflqqalaltffpelfdvrtsvgvdnrppqgsadagkr

    Sequence, based on observed residues (ATOM records): (download) 
    >3e08C (C:)
lrdlepgihtdlegrltyggylrldqllsaqqplsepahhdemlfiiqsqtselwlklla
helraaivhlqrdevwqcrkvlarskqvlrqlteqwsvletltpseymgfrdvlgpssgf
qslqyryiefllgnknpqmlqvfaydpagqarlrevleapslyeeflrylarfghaipqq
yqardwtaahvaddtlrpvferiyentdrywreyslcedlvdvetqfqlwrfrhmrtvmr
vigfkrgtggssgvgflqqalaltffpelfdvrtsvgvdn

  • Chain 'D':
    Sequence, based on SEQRES records: (download) 
    >3e08D (D:)
mpvdknlrdlepgihtdlegrltyggylrldqllsaqqplsepahhdemlfiiqsqtsel
wlkllahelraaivhlqrdevwqcrkvlarskqvlrqlteqwsvletltpseymgfrdvl
gpssgfqslqyryiefllgnknpqmlqvfaydpagqarlrevleapslyeeflrylarfg
haipqqyqardwtaahvaddtlrpvferiyentdrywreyslcedlvdvetqfqlwrfrh
mrtvmrvigfkrgtggssgvgflqqalaltffpelfdvrtsvgvdnrppqgsadagkr

    Sequence, based on observed residues (ATOM records): (download) 
    >3e08D (D:)
lrdlepgihtdlegrltyggylrldqllsaqqplsepahhdemlfiiqsqtselwlklla
helraaivhlqrdevwqcrkvlarskqvlrqlteqwsvletltpseymgfrdvlgpssgf
qslqyryiefllgnknpqmlqvfaydpagqarlrevleapslyeeflrylarfghaipqq
yqardwtaahvaddtlrpvferiyentdrywreyslcedlvdvetqfqlwrfrhmrtvmr
vigfkrgtggssgvgflqqalaltffpelfdvrtsvgvdn

  • Chain 'E':
    Sequence, based on SEQRES records: (download) 
    >3e08E (E:)
mpvdknlrdlepgihtdlegrltyggylrldqllsaqqplsepahhdemlfiiqsqtsel
wlkllahelraaivhlqrdevwqcrkvlarskqvlrqlteqwsvletltpseymgfrdvl
gpssgfqslqyryiefllgnknpqmlqvfaydpagqarlrevleapslyeeflrylarfg
haipqqyqardwtaahvaddtlrpvferiyentdrywreyslcedlvdvetqfqlwrfrh
mrtvmrvigfkrgtggssgvgflqqalaltffpelfdvrtsvgvdnrppqgsadagkr

    Sequence, based on observed residues (ATOM records): (download) 
    >3e08E (E:)
lrdlepgihtdlegrltyggylrldqllsaqqplsepahhdemlfiiqsqtselwlklla
helraaivhlqrdevwqcrkvlarskqvlrqlteqwsvletltpseymgfrdvlgpssgf
qslqyryiefllgnknpqmlqvfaydpagqarlrevleapslyeeflrylarfghaipqq
yqardwtaahvaddtlrpvferiyentdrywreyslcedlvdvetqfqlwrfrhmrtvmr
vigfkrgtggssgvgflqqalaltffpelfdvrtsvgv

  • Chain 'F':
    Sequence, based on SEQRES records: (download) 
    >3e08F (F:)
mpvdknlrdlepgihtdlegrltyggylrldqllsaqqplsepahhdemlfiiqsqtsel
wlkllahelraaivhlqrdevwqcrkvlarskqvlrqlteqwsvletltpseymgfrdvl
gpssgfqslqyryiefllgnknpqmlqvfaydpagqarlrevleapslyeeflrylarfg
haipqqyqardwtaahvaddtlrpvferiyentdrywreyslcedlvdvetqfqlwrfrh
mrtvmrvigfkrgtggssgvgflqqalaltffpelfdvrtsvgvdnrppqgsadagkr

    Sequence, based on observed residues (ATOM records): (download) 
    >3e08F (F:)
lrdlepgihtdlegrltyggylrldqllsaqqplsepahhdemlfiiqsqtselwlklla
helraaivhlqrdevwqcrkvlarskqvlrqlteqwsvletltpseymgfrdvlgpssgf
qslqyryiefllgnknpqmlqvfaydpagqarlrevleapslyeeflrylarfghaipqq
yqardwtaahvaddtlrpvferiyentdrywreyslcedlvdvetqfqlwrfrhmrtvmr
vigfkrgtggssgvgflqqalaltffpelfdvrtsv

  • Chain 'G':
    Sequence, based on SEQRES records: (download) 
    >3e08G (G:)
mpvdknlrdlepgihtdlegrltyggylrldqllsaqqplsepahhdemlfiiqsqtsel
wlkllahelraaivhlqrdevwqcrkvlarskqvlrqlteqwsvletltpseymgfrdvl
gpssgfqslqyryiefllgnknpqmlqvfaydpagqarlrevleapslyeeflrylarfg
haipqqyqardwtaahvaddtlrpvferiyentdrywreyslcedlvdvetqfqlwrfrh
mrtvmrvigfkrgtggssgvgflqqalaltffpelfdvrtsvgvdnrppqgsadagkr

    Sequence, based on observed residues (ATOM records): (download) 
    >3e08G (G:)
lrdlepgihtdlegrltyggylrldqllsaqqplsepahhdemlfiiqsqtselwlklla
helraaivhlqrdevwqcrkvlarskqvlrqlteqwsvletltpseymgfrdvlgpssgf
qslqyryiefllgnknpqmlqvfaydpagqarlrevleapslyeeflrylarfghaipqq
yqardwtaahvaddtlrpvferiyentdrywreyslcedlvdvetqfqlwrfrhmrtvmr
vigfkrgtggssgvgflqqalaltffpelfdvrtsvg

  • Chain 'H':
    Sequence, based on SEQRES records: (download) 
    >3e08H (H:)
mpvdknlrdlepgihtdlegrltyggylrldqllsaqqplsepahhdemlfiiqsqtsel
wlkllahelraaivhlqrdevwqcrkvlarskqvlrqlteqwsvletltpseymgfrdvl
gpssgfqslqyryiefllgnknpqmlqvfaydpagqarlrevleapslyeeflrylarfg
haipqqyqardwtaahvaddtlrpvferiyentdrywreyslcedlvdvetqfqlwrfrh
mrtvmrvigfkrgtggssgvgflqqalaltffpelfdvrtsvgvdnrppqgsadagkr

    Sequence, based on observed residues (ATOM records): (download) 
    >3e08H (H:)
lrdlepgihtdlegrltyggylrldqllsaqqplsepahhdemlfiiqsqtselwlklla
helraaivhlqrdevwqcrkvlarskqvlrqlteqwsvletltpseymgfrdvlgpssgf
qslqyryiefllgnknpqmlqvfaydpagqarlrevleapslyeeflrylarfghaipqq
yqardwtaahvaddtlrpvferiyentdrywreyslcedlvdvetqfqlwrfrhmrtvmr
vigfkrgtggssgvgflqqalaltffpelfdvrtsv