PDB entry 3dy8

View 3dy8 on RCSB PDB site
Description: Human Phosphodiesterase 9 in complex with product 5'-GMP (E+P complex)
Class: hydrolase
Keywords: phosphodiestrase, enzyme mechanism, cGMP, Hydrolase, Manganese, Metal-binding, Phosphoprotein
Deposited on 2008-07-25, released 2008-09-16
The last revision prior to the SCOPe 2.05 freeze date was dated 2011-07-13, with a file datestamp of 2011-05-08.
Experiment type: XRAY
Resolution: 2.15 Å
R-factor: 0.177
AEROSPACI score: 0.46 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: human phosphodiesterase 9
    Species: Homo sapiens [TaxId:9606]
    Gene: PDE9A
    Database cross-references and differences (RAF-indexed):
    • Uniprot O76083 (4-End)
      • expression tag (0-3)
    Domains in SCOPe 2.05: d3dy8a_
  • Chain 'B':
    Compound: human phosphodiesterase 9
    Species: Homo sapiens [TaxId:9606]
    Gene: PDE9A
    Database cross-references and differences (RAF-indexed):
    • Uniprot O76083 (4-End)
      • expression tag (0-3)
    Domains in SCOPe 2.05: d3dy8b_
  • Heterogens: MN, MG, 5GP, IBM, FMT, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download) 
    >3dy8A (A:)
gshmtypkyllspetiealrkptfdvwlwepnemlsclehmyhdlglvrdfsinpvtlrr
wlfcvhdnyrnnpfhnfrhcfcvaqmmysmvwlcslqekfsqtdililmtaaichdldhp
gynntyqinartelavryndisplenhhcavafqilaepecnifsnippdgfkqirqgmi
tlilatdmarhaeimdsfkekmenfdysneehmtllkmilikccdisnevrpmevaepwv
dclleeyfmqsdrekseglpvapfmdrdkvtkataqigfikfvlipmfetvtklfpmvee
imlqplwesrdryeelkriddamkelqkk

    Sequence, based on observed residues (ATOM records): (download) 
    >3dy8A (A:)
gshmtypkyllspetiealrkptfdvwlwepnemlsclehmyhdlglvrdfsinpvtlrr
wlfcvhdnyrnnpfhnfrhcfcvaqmmysmvwlcslqekfsqtdililmtaaichdldhp
gynntyqinartelavryndisplenhhcavafqilaepecnifsnippdgfkqirqgmi
tlilatdmarhaeimdsfkekmenfdysneehmtllkmilikccdisnevrpmevaepwv
dclleeyfmqsdrekseglpvapfmdrdkvtkataqigfikfvlipmfetvtklfpmvee
imlqplwesrdryeelkriddamkelqk

  • Chain 'B':
    Sequence, based on SEQRES records: (download) 
    >3dy8B (B:)
gshmtypkyllspetiealrkptfdvwlwepnemlsclehmyhdlglvrdfsinpvtlrr
wlfcvhdnyrnnpfhnfrhcfcvaqmmysmvwlcslqekfsqtdililmtaaichdldhp
gynntyqinartelavryndisplenhhcavafqilaepecnifsnippdgfkqirqgmi
tlilatdmarhaeimdsfkekmenfdysneehmtllkmilikccdisnevrpmevaepwv
dclleeyfmqsdrekseglpvapfmdrdkvtkataqigfikfvlipmfetvtklfpmvee
imlqplwesrdryeelkriddamkelqkk

    Sequence, based on observed residues (ATOM records): (download) 
    >3dy8B (B:)
gshmtypkyllspetiealrkptfdvwlwepnemlsclehmyhdlglvrdfsinpvtlrr
wlfcvhdnyrnnpfhnfrhcfcvaqmmysmvwlcslqekfsqtdililmtaaichdldhp
gynntyqinartelavryndisplenhhcavafqilaepecnifsnippdgfkqirqgmi
tlilatdmarhaeimdsfkekmenfdysneehmtllkmilikccdisnevrpmevaepwv
dclleeyfmqsdrekseglpvapfmdrdkvtkataqigfikfvlipmfetvtklfpmvee
imlqplwesrdryeelkriddamkelqk