PDB entry 3dx4

View 3dx4 on RCSB PDB site
Description: Golgi alpha-Mannosidase II in complex with Mannostatin analog (1R,2R,3R,4S,5R)-4-amino-5-methoxycyclopentane-1,2,3-triol
Class: hydrolase
Keywords: GH38 Glycosidase, Glycosidase, Golgi apparatus, Hydrolase, Membrane, Metal-binding, Signal-anchor, Transmembrane
Deposited on 2008-07-23, released 2009-07-07
The last revision prior to the SCOPe 2.05 freeze date was dated 2011-07-13, with a file datestamp of 2011-05-25.
Experiment type: XRAY
Resolution: 1.38 Å
R-factor: 0.188
AEROSPACI score: 0.68 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: Alpha-mannosidase 2
    Species: Drosophila melanogaster [TaxId:7227]
    Gene: alpha-Man-II, GmII, CG18802
    Database cross-references and differences (RAF-indexed):
    • Uniprot Q24451 (Start-1044)
      • see remark 999 (906)
    Domains in SCOPe 2.05: d3dx4a1, d3dx4a2, d3dx4a3
  • Heterogens: NAG, ZN, MRD, GOO, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download) 
    >3dx4A (A:)
rsshhhhhhgefddpirpplkvarsprpgqcqdvvqdvpnvdvqmlelydrmsfkdidgg
vwkqgwnikydplkynahhklkvfvvphshndpgwiqtfeeyyqhdtkhilsnalrhlhd
npemkfiwaeisyfarfyhdlgenkklqmksivkngqlefvtggwvmpdeanshwrnvll
qltegqtwlkqfmnvtptaswaidpfghsptmpyilqksgfknmliqrthysvkkelaqq
rqleflwrqiwdnkgdtalfthmmpfysydiphtcgpdpkvccqfdfkrmgsfglscpwk
vpprtisdqnvaarsdllvdqwkkkaelyrtnvlliplgddfrfkqntewdvqrvnyerl
fehinsqahfnvqaqfgtlqeyfdavhqaeragqaefptlsgdfftyadrsdnywsgyyt
srpyhkrmdrvlmhyvraaemlsawhswdgmarieerleqarrelslfqhhdgitgtakt
hvvvdyeqrmqealkacqmvmqqsvyrlltkpsiyspdfsfsyftlddsrwpgsgvedsr
ttiilgedilpskhvvmhntlphwreqlvdfyvsspfvsvtdlannpveaqvspvwswhh
dtltktihpqgsttkyriifkarvppmglatyvltisdskpehtsyasnlllrknptslp
lgqypedvkfgdpreislrvgngptlafseqgllksiqltqdsphvpvhfkflkygvrsh
gdrsgaylflpngpaspvelgqpvvlvtkgklessvsvglpsvvhqtimrggapeirnlv
digsldnteivmrlethidsgdifytdlnglqfikrrrldklplqanyypipsgmfieda
ntrltlltgqplggsslasgeleimqdrrlasdderglgqgvldnkpvlhiyrlvlekvn
ncvrpsklhpagyltsaahkasqslldpldkfifaenewigaqgqfggdhpsaredldvs
vmrrltkssaktqrvgyvlhrtnlmqcgtpeehtqkldvchllpnvarcerttltflqnl
ehldgmvapevcpmetaayvsshss

    Sequence, based on observed residues (ATOM records): (download) 
    >3dx4A (A:)
qcqdvvqdvpnvdvqmlelydrmsfkdidggvwkqgwnikydplkynahhklkvfvvphs
hndpgwiqtfeeyyqhdtkhilsnalrhlhdnpemkfiwaeisyfarfyhdlgenkklqm
ksivkngqlefvtggwvmpdeanshwrnvllqltegqtwlkqfmnvtptaswaidpfghs
ptmpyilqksgfknmliqrthysvkkelaqqrqleflwrqiwdnkgdtalfthmmpfysy
diphtcgpdpkvccqfdfkrmgsfglscpwkvpprtisdqnvaarsdllvdqwkkkaely
rtnvlliplgddfrfkqntewdvqrvnyerlfehinsqahfnvqaqfgtlqeyfdavhqa
eragqaefptlsgdfftyadrsdnywsgyytsrpyhkrmdrvlmhyvraaemlsawhswd
gmarieerleqarrelslfqhhdgitgtakthvvvdyeqrmqealkacqmvmqqsvyrll
tkpsiyspdfsfsyftlddsrwpgsgvedsrttiilgedilpskhvvmhntlphwreqlv
dfyvsspfvsvtdlannpveaqvspvwswhhdtltktihpqgsttkyriifkarvppmgl
atyvltisdskpehtsyasnlllrknptslplgqypedvkfgdpreislrvgngptlafs
eqgllksiqltqdsphvpvhfkflkygvrshgdrsgaylflpngpaspvelgqpvvlvtk
gklessvsvglpsvvhqtimrggapeirnlvdigsldnteivmrlethidsgdifytdln
glqfikrrrldklplqanyypipsgmfiedantrltlltgqplggsslasgeleimqdrr
lasdderglgqgvldnkpvlhiyrlvlekvnncvrpsklhpagyltsaahkasqslldpl
dkfifaenewigaqgqfggdhpsaredldvsvmrrltkssaktqrvgyvlhrtnlmqcgt
peehtqkldvchllpnvarcerttltflqnlehldgmvapevcpmetaayvsshss