PDB entry 3dwg

View 3dwg on RCSB PDB site
Description: Crystal structure of a sulfur carrier protein complex found in the cysteine biosynthetic pathway of Mycobacterium tuberculosis
Class: transferase
Keywords: Sulfur carrier protein complex, beta-grasp fold, Amino-acid biosynthesis, Cysteine biosynthesis, Pyridoxal phosphate, Transferase
Deposited on 2008-07-22, released 2008-09-23
The last revision prior to the SCOPe 2.08 freeze date was dated 2011-07-13, with a file datestamp of 2011-05-08.
Experiment type: XRAY
Resolution: 1.53 Å
R-factor: 0.178
AEROSPACI score: 0.62 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: Cysteine synthase B
    Species: Mycobacterium tuberculosis [TaxId:83332]
    Gene: cysM, Rv1336, MT1377, MTCY130.21
    Database cross-references and differences (RAF-indexed):
    • Uniprot P63873 (2-324)
      • expression tag (0-1)
    Domains in SCOPe 2.08: d3dwga1, d3dwga2
  • Chain 'B':
    Compound: Cysteine synthase B
    Species: Mycobacterium tuberculosis [TaxId:83332]
    Gene: cysM, Rv1336, MT1377, MTCY130.21
    Database cross-references and differences (RAF-indexed):
    • Uniprot P63873 (2-324)
      • expression tag (0-1)
    Domains in SCOPe 2.08: d3dwgb1, d3dwgb2
  • Chain 'C':
    Compound: 9.5 kDa culture filtrate antigen cfp10A
    Species: Mycobacterium tuberculosis [TaxId:83332]
    Gene: cfp10A, Rv1335, MT1376.1, MTCY130.20
    Database cross-references and differences (RAF-indexed):
  • Heterogens: PLP, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence; same for both SEQRES and ATOM records: (download) 
    >3dwgA (A:)
rhmtrydsllqalgntplvglqrlsprwddgrdgphvrlwakledrnptgsikdrpavrm
ieqaeadgllrpgatileptsgntgislamaarlkgyrlicvmpentsverrqllelyga
qiifsaaeggsntavatakelaatnpswvmlyqygnpantdshycgtgpelladlpeith
fvaglgttgtlmgtgrflrehvanvkivaaeprygegvyalrnmdegfvpelydpeilta
rysvgavdavrrtrelvhtegifagistgavlhaalgvgagalaageradialvvadagw
kylstgayagslddaetalegqlwa

  • Chain 'B':
    Sequence, based on SEQRES records: (download) 
    >3dwgB (B:)
rhmtrydsllqalgntplvglqrlsprwddgrdgphvrlwakledrnptgsikdrpavrm
ieqaeadgllrpgatileptsgntgislamaarlkgyrlicvmpentsverrqllelyga
qiifsaaeggsntavatakelaatnpswvmlyqygnpantdshycgtgpelladlpeith
fvaglgttgtlmgtgrflrehvanvkivaaeprygegvyalrnmdegfvpelydpeilta
rysvgavdavrrtrelvhtegifagistgavlhaalgvgagalaageradialvvadagw
kylstgayagslddaetalegqlwa

    Sequence, based on observed residues (ATOM records): (download) 
    >3dwgB (B:)
rhmtrydsllqalgntplvglqrlsprwddgrdgphvrlwakledrnptgsikdrpavrm
ieqaeadgllrpgatileptsgntgislamaarlkgyrlicvmpentsverrqllelyga
qiifsaantavatakelaatnpswvmlyqygnpantdshycgtgpelladlpeithfvag
lgttgtlmgtgrflrehvanvkivaaeprygegvyalrnmdegfvpelydpeiltarysv
gavdavrrtrelvhtegifagistgavlhaalgvgagalaageradialvvadagwkyls
tgayagslddaetalegqlwa

  • Chain 'C':
    No sequence available.