PDB entry 3dut

View 3dut on RCSB PDB site
Description: The high salt (phosphate) crystal structure of deoxy hemoglobin E (GLU26LYS) at physiological pH (pH 7.35)
Class: oxygen binding
Keywords: hemoglobin E oxygen transport beta thalassemia physiological, Disease mutation, Glycation, Glycoprotein, Heme, Iron, Metal-binding, Oxygen transport, Transport, Hypotensive agent, Pyruvate, S-nitrosylation, Vasoactive, OXYGEN BINDING
Deposited on 2008-07-17, released 2009-08-04
The last revision prior to the SCOPe 2.04 freeze date was dated 2011-07-13, with a file datestamp of 2011-05-08.
Experiment type: XRAY
Resolution: 1.55 Å
R-factor: 0.221
AEROSPACI score: 0.55 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: Hemoglobin subunit alpha
    Species: Homo sapiens [TaxId:9606]
    Gene: HBA1, HBA2
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.04: d3duta_
  • Chain 'B':
    Compound: Hemoglobin subunit beta
    Species: Homo sapiens [TaxId:9606]
    Gene: HBB
    Database cross-references and differences (RAF-indexed):
    • Uniprot P68871 (0-145)
      • engineered (25)
    Domains in SCOPe 2.04: d3dutb_
  • Chain 'C':
    Compound: Hemoglobin subunit alpha
    Species: Homo sapiens [TaxId:9606]
    Gene: HBA1, HBA2
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.04: d3dutc_
  • Chain 'D':
    Compound: Hemoglobin subunit beta
    Species: Homo sapiens [TaxId:9606]
    Gene: HBB
    Database cross-references and differences (RAF-indexed):
    • Uniprot P68871 (0-145)
      • engineered (25)
    Domains in SCOPe 2.04: d3dutd_
  • Heterogens: PO4, HEM, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence; same for both SEQRES and ATOM records: (download)
    >3dutA (A:)
    vlspadktnvkaawgkvgahageygaealermflsfpttktyfphfdlshgsaqvkghgk
    kvadaltnavahvddmpnalsalsdlhahklrvdpvnfkllshcllvtlaahlpaeftpa
    vhasldkflasvstvltskyr
    

  • Chain 'B':
    Sequence; same for both SEQRES and ATOM records: (download)
    >3dutB (B:)
    vhltpeeksavtalwgkvnvdevggkalgrllvvypwtqrffesfgdlstpdavmgnpkv
    kahgkkvlgafsdglahldnlkgtfatlselhcdklhvdpenfrllgnvlvcvlahhfgk
    eftppvqaayqkvvagvanalahkyh
    

  • Chain 'C':
    Sequence; same for both SEQRES and ATOM records: (download)
    >3dutC (C:)
    vlspadktnvkaawgkvgahageygaealermflsfpttktyfphfdlshgsaqvkghgk
    kvadaltnavahvddmpnalsalsdlhahklrvdpvnfkllshcllvtlaahlpaeftpa
    vhasldkflasvstvltskyr
    

  • Chain 'D':
    Sequence; same for both SEQRES and ATOM records: (download)
    >3dutD (D:)
    vhltpeeksavtalwgkvnvdevggkalgrllvvypwtqrffesfgdlstpdavmgnpkv
    kahgkkvlgafsdglahldnlkgtfatlselhcdklhvdpenfrllgnvlvcvlahhfgk
    eftppvqaayqkvvagvanalahkyh