PDB entry 3dtq

View 3dtq on RCSB PDB site
Description: Engineered human lipocalin 2 with specificity for Y-DTPA, apo-form
Class: transport protein
Keywords: protein design, ligand binding protein, beta barrel, engineered lipocalin, de novo protein, protein binding, Glycoprotein, Pyrrolidone carboxylic acid, Secreted, TRANSPORT PROTEIN
Deposited on 2008-07-15, released 2009-05-12
The last revision prior to the SCOPe 2.08 freeze date was dated 2009-05-12, with a file datestamp of 2009-05-08.
Experiment type: XRAY
Resolution: 2.5 Å
R-factor: 0.262
AEROSPACI score: 0.26 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: Neutrophil gelatinase-associated lipocalin
    Species: Homo sapiens [TaxId:9606]
    Gene: LCN2, HNL, NGAL
    Database cross-references and differences (RAF-indexed):
    • Uniprot P80188 (Start-177)
      • engineered (27)
      • engineered (32)
      • engineered (35)
      • engineered (40)
      • engineered (51)
      • engineered (53)
      • engineered (67)
      • engineered (69)
      • engineered (78-80)
      • engineered (86)
      • engineered (133)
      • engineered (137)
      • engineered (144)
    Domains in SCOPe 2.08: d3dtqa_
  • Chain 'B':
    Compound: Neutrophil gelatinase-associated lipocalin
    Species: Homo sapiens [TaxId:9606]
    Gene: LCN2, HNL, NGAL
    Database cross-references and differences (RAF-indexed):
    • Uniprot P80188
      • engineered (27)
      • engineered (32)
      • engineered (35)
      • engineered (40)
      • engineered (51)
      • engineered (53)
      • engineered (67)
      • engineered (69)
      • engineered (78-80)
      • engineered (86)
      • engineered (133)
      • engineered (137)
      • engineered (144)
    Domains in SCOPe 2.08: d3dtqb_
  • Chain 'C':
    Compound: Neutrophil gelatinase-associated lipocalin
    Species: Homo sapiens [TaxId:9606]
    Gene: LCN2, HNL, NGAL
    Database cross-references and differences (RAF-indexed):
    • Uniprot P80188 (0-End)
      • engineered (27)
      • engineered (32)
      • engineered (35)
      • engineered (40)
      • engineered (51)
      • engineered (53)
      • engineered (67)
      • engineered (69)
      • engineered (78-80)
      • engineered (86)
      • engineered (133)
      • engineered (137)
      • engineered (144)
    Domains in SCOPe 2.08: d3dtqc_
  • Heterogens: HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download) 
    >3dtqA (A:)
qdstsdlipapplskvplqqnfqdnqfhgkwyqvgragnaalredkdpqkmtaqiyelke
dksynvtavrfrkkkcdyatmtfvpgsqpgeftlgniksypgltsylvrvvstnynqham
vffkkvsqnreyfsitllgrtkelaselkenfirfskslglpenhivfpvpidqcidgsa
hhhhhh

    Sequence, based on observed residues (ATOM records): (download) 
    >3dtqA (A:)
stsdlipapplskvplqqnfqdnqfhgkwyqvgragnaalpqkmtaqiyelkedksynvt
avrfrkkkcdyatmtfvpgsqpgeftlgniksypgltsylvrvvstnynqhamvffkkvs
qnreyfsitllgrtkelaselkenfirfskslglpenhivfpvpidqcidg

  • Chain 'B':
    Sequence, based on SEQRES records: (download) 
    >3dtqB (B:)
qdstsdlipapplskvplqqnfqdnqfhgkwyqvgragnaalredkdpqkmtaqiyelke
dksynvtavrfrkkkcdyatmtfvpgsqpgeftlgniksypgltsylvrvvstnynqham
vffkkvsqnreyfsitllgrtkelaselkenfirfskslglpenhivfpvpidqcidgsa
hhhhhh

    Sequence, based on observed residues (ATOM records): (download) 
    >3dtqB (B:)
stsdlipapplskvplqqnfqdnqfhgkwyqvgragnaaqkmtaqiyelkedksynvtav
rfrkkkcdyatmtfvpgsqpgeftlgniksypgltsylvrvvstnynqhamvffkkvsqn
reyfsitllgrtkelaselkenfirfskslglpenhivfpvpidqcid

  • Chain 'C':
    Sequence, based on SEQRES records: (download) 
    >3dtqC (C:)
qdstsdlipapplskvplqqnfqdnqfhgkwyqvgragnaalredkdpqkmtaqiyelke
dksynvtavrfrkkkcdyatmtfvpgsqpgeftlgniksypgltsylvrvvstnynqham
vffkkvsqnreyfsitllgrtkelaselkenfirfskslglpenhivfpvpidqcidgsa
hhhhhh

    Sequence, based on observed residues (ATOM records): (download) 
    >3dtqC (C:)
qdstsdlipapplskvplqqnfqdnqfhgkwyqvgragnaalpqkmtaqiyelkedksyn
vtavrfrkkkcdyatmtfvpgsqpgeftlgniksypgltsylvrvvstnynqhamvffkk
vsqnreyfsitllgrtkelaselkenfirfskslglpenhivfpvpidqcid