PDB entry 3drw

View 3drw on RCSB PDB site
Description: Crystal Structure of a Phosphofructokinase from Pyrococcus horikoshii OT3 with AMP
Class: transferase
Keywords: 6-phosphofructokinase, Pyrococcus horikoshii, AMP, ADP, Glycolysis, Kinase, Magnesium, Metal-binding, Transferase, Structural Genomics, PSI-2, Protein Structure Initiative, Midwest Center for Structural Genomics, MCSG
Deposited on 2008-07-11, released 2008-12-23
The last revision prior to the SCOPe 2.08 freeze date was dated 2012-10-17, with a file datestamp of 2012-10-12.
Experiment type: XRAY
Resolution: 1.9 Å
R-factor: 0.174
AEROSPACI score: 0.5 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: ADP-specific phosphofructokinase
    Species: Pyrococcus horikoshii [TaxId:53953]
    Gene: pfkC, PH1645
    Database cross-references and differences (RAF-indexed):
    • Uniprot O59355 (22-471)
      • expression tag (11-20)
      • engineered (38)
    Domains in SCOPe 2.08: d3drwa1, d3drwa2
  • Chain 'B':
    Compound: ADP-specific phosphofructokinase
    Species: Pyrococcus horikoshii [TaxId:53953]
    Gene: pfkC, PH1645
    Database cross-references and differences (RAF-indexed):
    • Uniprot O59355 (22-471)
      • engineered (38)
    Domains in SCOPe 2.08: d3drwb_
  • Heterogens: AMP, NA, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download) 
    >3drwA (A:)
mgsshhhhhhssgrenlyfqghmipehlsiytaynaniaaivklnqetiqnlinafdpde
vkrrieeypreinepidfvarlvhtlklgkpaavplvnekmnewfdktfryeeerlggqa
giiantlaglkirkviaytpflpkrlaelfkkgvlypvvengelqfkpiqeayregdplk
inrifefrkglkfklgdetieipnsgrfivsarfesisrietredikpflgeigkevdga
ifsgyqglrtkysdgkdanyylrrakediiefkekdvkihvefasvqdrklrkkiitnil
pfvdsvgideaeiaqilsvlgyreladriftynrledsilggmiildelnfeilqvhtty
ylmyithrdnplseeelakslefgttlaaaraslgdirgpddykvglkvpfnerseyvkl
rfeeaksrlrmreykvvviptrlvqnpvltvglgdtisagafltyleflkrhgs

    Sequence, based on observed residues (ATOM records): (download) 
    >3drwA (A:)
sgrenlyfqgmipehlsiytaynaniaaivklnqetiqnlinafdpdevkrrieeyprei
nepidfvarlvhtlklgkpaavplvnekmnewfdktfryeeerlggqagiiantlaglki
rkviaytpflpkrlaelfkkgvlypvvengelqfkpiqeayregdplkinrifefrkglk
fklgdetieipnsgrfivsarfesisrietredikpflgeigkevdgaifsgyqglrtky
sdgkdanyylrrakediiefkekdvkihvefasvqdrklrkkiitnilpfvdsvgideae
iaqilsvlgyreladriftynrledsilggmiildelnfeilqvhttyylmyithrdnpl
seeelakslefgttlaaaraslgdirgpddykvglkvpfnerseyvklrfeeaksrlrmr
eykvvviptrlvqnpvltvglgdtisagafltyleflkrh

  • Chain 'B':
    Sequence, based on SEQRES records: (download) 
    >3drwB (B:)
mgsshhhhhhssgrenlyfqghmipehlsiytaynaniaaivklnqetiqnlinafdpde
vkrrieeypreinepidfvarlvhtlklgkpaavplvnekmnewfdktfryeeerlggqa
giiantlaglkirkviaytpflpkrlaelfkkgvlypvvengelqfkpiqeayregdplk
inrifefrkglkfklgdetieipnsgrfivsarfesisrietredikpflgeigkevdga
ifsgyqglrtkysdgkdanyylrrakediiefkekdvkihvefasvqdrklrkkiitnil
pfvdsvgideaeiaqilsvlgyreladriftynrledsilggmiildelnfeilqvhtty
ylmyithrdnplseeelakslefgttlaaaraslgdirgpddykvglkvpfnerseyvkl
rfeeaksrlrmreykvvviptrlvqnpvltvglgdtisagafltyleflkrhgs

    Sequence, based on observed residues (ATOM records): (download) 
    >3drwB (B:)
mipehlsiytaynaniaaivklnqetiqnlinafdpdevkrrieeypreinepidfvarl
vhtlklgkpaavplvnekmnewfdktfryeeerlggqagiiantlaglkirkviaytpfl
pkrlaelfkkgvlypvvengelqfkpiqeayregdplkinrifefrkglkfklgdetiei
pnsgrfivsarfesisrietredikpflgeigkevdgaifsgyqglrtkysdgkdanyyl
rrakediiefkekdvkihvefasvqdrklrkkiitnilpfvdsvgideaeiaqilsvlgy
reladriftynrledsilggmiildelnfeilqvhttyylmyithrdnplseeelaksle
fgttlaaaraslgdirgpddykvglkvpfnerseyvklrfeeaksrlrmreykvvviptr
lvqnpvltvglgdtisagafltyleflkrh