PDB entry 3dox

View 3dox on RCSB PDB site
Description: x-ray structure of hiv-1 protease in situ product complex
Deposited on 2008-07-07, released 2008-09-09
The last revision was dated 2021-11-10, with a file datestamp of 2021-11-05.
Experiment type: XRAY
Resolution: 2 Å
R-factor: N/A
AEROSPACI score: 0.31 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: hiv-1 protease
    Species: Human immunodeficiency virus type 1 (isolate HXB2 group M subtype B) [TaxId:11706]
    Gene: gag-pol
    Database cross-references and differences (RAF-indexed):
    • Uniprot P04585 (104-202)
      • engineered mutation (94)
      • see remark 999 (99-103)
      • engineered mutation (198)
  • Chain 'P':
    Compound: a peptide substrate-sqny
    Species: synthetic, synthetic
    Database cross-references and differences (RAF-indexed):
    • PDB 3DOX (0-3)
  • Chain 'Q':
    Compound: a peptide substrate-piv
    Species: synthetic, synthetic
    Database cross-references and differences (RAF-indexed):
    • PDB 3DOX (0-2)
  • Heterogens: HOH

PDB Chain Sequences:
This PDB entry is not classified in SCOPe 2.08, so the chain sequences below are not included in the ASTRAL sequence sets.

  • Chain 'A':
    Sequence, based on SEQRES records:
    >3doxA (A:)
pqvtlwqrplvtikiggqlkealldtgaddtvleemslpgrwkpkmiggiggfikvrqyd
qilieicghkaigtvlvgptpvniigrnlltqigmtlnfggssgpqvtlwqrplvtikig
gqlkealldtgaddtvleemslpgrwkpkmiggiggfikvrqydqilieicghkaigtvl
vgptpvniigrnlltqigatlnf

    Sequence, based on observed residues (ATOM records):
    >3doxA (A:)
pqvtlwqrplvtikiggqlkealldtgaddtvleemslpgrwkpkmiggiggfikvrqyd
qilieicghkaigtvlvgptpvniigrnlltqigmtlnfpqvtlwqrplvtikiggqlke
alldtgaddtvleemslpgrwkpkmiggiggfikvrqydqilieicghkaigtvlvgptp
vniigrnlltqigatlnf

  • Chain 'P':
    Sequence; same for both SEQRES and ATOM records:
    >3doxP (P:)
sqny

  • Chain 'Q':
    Sequence; same for both SEQRES and ATOM records:
    >3doxQ (Q:)
piv