PDB entry 3dmj

View 3dmj on RCSB PDB site
Description: CRYSTAL STRUCTURE OF HIV-1 V106A and Y181C MUTANT REVERSE TRANSCRIPTASE IN COMPLEX WITH GW564511.
Class: transferase
Keywords: HIV-1 REVERSE TRANSCRIPTASE, AIDS, NNRTI, GW564511, DRUG RESISTANCE, Hydrolase, Transferase
Deposited on 2008-07-01, released 2008-08-12
The last revision prior to the SCOPe 2.08 freeze date was dated 2009-02-24, with a file datestamp of 2009-02-03.
Experiment type: XRAY
Resolution: 2.6 Å
R-factor: 0.197
AEROSPACI score: 0.31 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: Reverse transcriptase/ribonuclease H
    Species: Human immunodeficiency virus type 1 [TaxId:11706]
    Gene: gag-pol
    Database cross-references and differences (RAF-indexed):
    • Uniprot P04585 (0-End)
      • engineered (105)
      • engineered (180)
    Domains in SCOPe 2.08: d3dmja1, d3dmja2
  • Chain 'B':
    Compound: p51 RT
    Species: Human immunodeficiency virus type 1 [TaxId:11706]
    Gene: gag-pol
    Database cross-references and differences (RAF-indexed):
    • Uniprot P04585
      • engineered (105)
      • engineered (180)
    Domains in SCOPe 2.08: d3dmjb_
  • Heterogens: PO4, GWE, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download) 
    >3dmjA (A:)
pispietvpvklkpgmdgpkvkqwplteekikalveictemekegkiskigpenpyntpv
faikkkdstkwrklvdfrelnkrtqdfwevqlgiphpaglkkkksatvldvgdayfsvpl
dedfrkytaftipsinnetpgiryqynvlpqgwkgspaifqssmtkilepfrkqnpdivi
cqymddlyvgsdleigqhrtkieelrqhllrwglttpdkkhqkeppflwmgyelhpdkwt
vqpivlpekdswtvndiqklvgklnwasqiypgikvrqlckllrgtkalteviplteeae
lelaenreilkepvhgvyydpskdliaeiqkqgqgqwtyqiyqepfknlktgkyarmrga
htndvkqlteavqkittesiviwgktpkfklpiqketwetwwteywqatwipewefvntp
plvklwyqlekepivgaetfyvdgaanretklgkagyvtnrgrqkvvtltdttnqktelq
aiylalqdsglevnivtdsqyalgiiqaqpdqseselvnqiieqlikkekvylawvpahk
giggneqvdklvsagirkvl

    Sequence, based on observed residues (ATOM records): (download) 
    >3dmjA (A:)
pispietvpvklkpgmdgpkvkqwplteekikalveictemekegkiskigpenpyntpv
faikkwrklvdfrelnkrtqdfwevqlgiphpaglkkkksatvldvgdayfsvpldedfr
kytaftipsietpgiryqynvlpqgwkgspaifqssmtkilepfrkqnpdivicqymddl
yvgsdleigqhrtkieelrqhllrwglttpdkkhqkeppflwmgyelhpdkwtvqpivlp
ekdswtvndiqklvgklnwasqiypgikvrqlckllrgtkalteviplteeaelelaenr
eilkepvhgvyydpskdliaeiqkqgqgqwtyqiyqepfknlktgkyarmrgahtndvkq
lteavqkittesiviwgktpkfklpiqketwetwwteywqatwipewefvntpplvklwy
qlekepivgaetfyvdgaanretklgkagyvtnrgrqkvvtltdttnqktelqaiylalq
dsglevnivtdsqyalgiiqaqpdqseselvnqiieqlikkekvylawvpah

  • Chain 'B':
    Sequence, based on SEQRES records: (download) 
    >3dmjB (B:)
pispietvpvklkpgmdgpkvkqwplteekikalveictemekegkiskigpenpyntpv
faikkkdstkwrklvdfrelnkrtqdfwevqlgiphpaglkkkksatvldvgdayfsvpl
dedfrkytaftipsinnetpgiryqynvlpqgwkgspaifqssmtkilepfrkqnpdivi
cqymddlyvgsdleigqhrtkieelrqhllrwglttpdkkhqkeppflwmgyelhpdkwt
vqpivlpekdswtvndiqklvgklnwasqiypgikvrqlckllrgtkalteviplteeae
lelaenreilkepvhgvyydpskdliaeiqkqgqgqwtyqiyqepfknlktgkyarmrga
htndvkqlteavqkittesiviwgktpkfklpiqketwetwwteywqatwipewefvntp
plvklwyqlekepivgaetf

    Sequence, based on observed residues (ATOM records): (download) 
    >3dmjB (B:)
tvpvklkpgmdgpkvkqwplteekikalveictemekegkiskigpenpyntpvfaiktk
wrklvdfrelnkrtqdfwphpaglkkkksatvldvgdayfsvpldedfrkytaftipsin
netpgiryqynvlpqgwkgspaifqssmtkilepfrkqnpdivicqymddlyvgsdleig
qhrtkieelrqhllrwelhpdkwtvqpivlpekdswtvndiqklvgklnwasqiypgikv
rqlckllrgtkalteviplteeaelelaenreilkepvhgvyydpskdliaeiqkqgqgq
wtyqiyqepfknlktgkyarmrgahtndvkqlteavqkittesiviwgktpkfklpiqke
twetwwteywqatwipewefvntpplvklwyqlekepivga