PDB entry 3djz

View 3djz on RCSB PDB site
Description: Crystal structure of transthyretin variant L55P at neutral pH
Class: transport protein
Keywords: TTR, AMYLOID FIBRILS, POINT MUTATION, TRANSPORT PROTEIN, Amyloid, Disease mutation, Gamma-carboxyglutamic acid, Glycoprotein, Hormone, Polyneuropathy, Retinol-binding, Secreted, Thyroid hormone, Transport, Vitamin A
Deposited on 2008-06-24, released 2009-07-14
The last revision prior to the SCOPe 2.07 freeze date was dated 2014-03-05, with a file datestamp of 2014-02-28.
Experiment type: XRAY
Resolution: 1.82 Å
R-factor: 0.197
AEROSPACI score: 0.41 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: Transthyretin
    Species: Homo sapiens [TaxId:9606]
    Database cross-references and differences (RAF-indexed):
    • Uniprot P02766
      • engineered (54)
    Domains in SCOPe 2.07: d3djza_
  • Chain 'B':
    Compound: Transthyretin
    Species: Homo sapiens [TaxId:9606]
    Database cross-references and differences (RAF-indexed):
    • Uniprot P02766
      • engineered (54)
    Domains in SCOPe 2.07: d3djzb_
  • Heterogens: HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download) 
    >3djzA (A:)
gptgtgeskcplmvkvldavrgspainvavhvfrkaaddtwepfasgktsesgephgltt
eeefvegiykveidtksywkalgispfhehaevvftandsgprrytiaallspysystta
vvtnpke

    Sequence, based on observed residues (ATOM records): (download) 
    >3djzA (A:)
cplmvkvldavrgspainvavhvfrkaaddtwepfasgktsesgephgltteeefvegiy
kveidtksywkalgispfhehaevvftandsgprrytiaallspysysttavvtnp

  • Chain 'B':
    Sequence, based on SEQRES records: (download) 
    >3djzB (B:)
gptgtgeskcplmvkvldavrgspainvavhvfrkaaddtwepfasgktsesgephgltt
eeefvegiykveidtksywkalgispfhehaevvftandsgprrytiaallspysystta
vvtnpke

    Sequence, based on observed residues (ATOM records): (download) 
    >3djzB (B:)
cplmvkvldavrgspainvavhvfrkaaddtwepfasgktsesgephgltteeefvegiy
kveidtksywkalgispfhehaevvftandsgprrytiaallspysysttavvtn