PDB entry 3djs

View 3djs on RCSB PDB site
Description: Crystal structure of transthyretin variant L58H at acidic pH
Class: transport protein
Keywords: TTR, AMYLOID FIBRILS, POINT MUTATION, TRANSPORT PROTEIN, Amyloid, Disease mutation, Gamma-carboxyglutamic acid, Glycoprotein, Hormone, Polymorphism, Polyneuropathy, Retinol-binding, Secreted, Thyroid hormone, Transport, Vitamin A
Deposited on 2008-06-24, released 2009-07-14
The last revision prior to the SCOPe 2.03 freeze date was dated 2009-07-14, with a file datestamp of 2009-07-10.
Experiment type: XRAY
Resolution: 1.8 Å
R-factor: 0.205
AEROSPACI score: 0.48 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: Transthyretin
    Species: Homo sapiens [TaxId:9606]
    Database cross-references and differences (RAF-indexed):
    • Uniprot P02766
      • engineered (57)
    Domains in SCOPe 2.03: d3djsa_
  • Chain 'B':
    Compound: Transthyretin
    Species: Homo sapiens [TaxId:9606]
    Database cross-references and differences (RAF-indexed):
    • Uniprot P02766
      • engineered (57)
    Domains in SCOPe 2.03: d3djsb_
  • Heterogens: HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download)
    >3djsA (A:)
    gptgtgeskcplmvkvldavrgspainvavhvfrkaaddtwepfasgktsesgelhghtt
    eeefvegiykveidtksywkalgispfhehaevvftandsgprrytiaallspysystta
    vvtnpke
    

    Sequence, based on observed residues (ATOM records): (download)
    >3djsA (A:)
    cplmvkvldavrgspainvavhvfrkaaddtwepfasgktsesgelhghtteeefvegiy
    kveidtksywkalgispfhehaevvftandsgprrytiaallspysysttavvtnp
    

  • Chain 'B':
    Sequence, based on SEQRES records: (download)
    >3djsB (B:)
    gptgtgeskcplmvkvldavrgspainvavhvfrkaaddtwepfasgktsesgelhghtt
    eeefvegiykveidtksywkalgispfhehaevvftandsgprrytiaallspysystta
    vvtnpke
    

    Sequence, based on observed residues (ATOM records): (download)
    >3djsB (B:)
    cplmvkvldavrgspainvavhvfrkaaddtwepfasgktsesgelhghtteeefvegiy
    kveidtksywkalgispfhehaevvftandsgprrytiaallspysysttavvtnp