PDB entry 3dhy

View 3dhy on RCSB PDB site
Description: Crystal Structures of Mycobacterium tuberculosis S-Adenosyl-L-Homocysteine Hydrolase in Ternary Complex with Substrate and Inhibitors
Deposited on 2008-06-19, released 2008-09-09
The last revision was dated 2010-05-19, with a file datestamp of 2010-05-14.
Experiment type: XRAY
Resolution: 2 Å
R-factor: 0.264
AEROSPACI score: 0.35 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: Adenosylhomocysteinase
    Species: Mycobacterium tuberculosis [TaxId:1773]
    Gene: ahcY, sahH, Rv3248c, MT3346, MTCY20B11.23c
    Database cross-references and differences (RAF-indexed):
  • Chain 'B':
    Compound: Adenosylhomocysteinase
    Species: Mycobacterium tuberculosis [TaxId:1773]
    Gene: ahcY, sahH, Rv3248c, MT3346, MTCY20B11.23c
    Database cross-references and differences (RAF-indexed):
  • Chain 'C':
    Compound: Adenosylhomocysteinase
    Species: Mycobacterium tuberculosis [TaxId:1773]
    Gene: ahcY, sahH, Rv3248c, MT3346, MTCY20B11.23c
    Database cross-references and differences (RAF-indexed):
  • Chain 'D':
    Compound: Adenosylhomocysteinase
    Species: Mycobacterium tuberculosis [TaxId:1773]
    Gene: ahcY, sahH, Rv3248c, MT3346, MTCY20B11.23c
    Database cross-references and differences (RAF-indexed):
  • Heterogens: 3DH, NAD, HOH

PDB Chain Sequences:
This PDB entry is not classified in SCOPe 2.08, so the chain sequences below are not included in the ASTRAL sequence sets.

  • Chain 'A':
    Sequence, based on SEQRES records:
    >3dhyA (A:)
mtgnlvtknsltpdvrngidfkiadlsladfgrkelriaehempglmslrreyaevqplk
garisgslhmtvqtavlietltalgaevrwascnifstqdhaaaavvvgphgtpdepkgv
pvfawkgetleeywwaaeqmltwpdpdkpanmilddggdatmlvlrgmqyekagvvppae
eddpaewkvflnllrtrfetdkdkwtkiaesvkgvteetttgvlrlyqfaaagdlafpai
nvndsvtkskfdnkygtrhslidginrgtdaliggkkvlicgygdvgkgcaeamkgqgar
vsvteidpinalqammegfdvvtveeaigdadivvtatgnkdiimlehikamkdhailgn
ighfdneidmaglersgatrvnvkpqvdlwtfgdtgrsiivlsegrllnlgnatghpsfv
msnsfanqtiaqielwtkndeydnevyrlpkhldekvarihvealgghltkltkeqaeyl
gvdvegpykpdhyry

    Sequence, based on observed residues (ATOM records):
    >3dhyA (A:)
sltpdvrngidfkiadlsladfgrkelriaehempglmslrreyaevqplkgarisgslh
mtvqtavlietltalgaevrwascnifstqdhaaaavvvgphgtpdepkgvpvfawkget
leeywwaaeqmltwpdpdkpanmilddggdatmlvlrgmqyekagvvppaeeddpaewkv
flnllrtrfetdkdkwtkiaesvkgvteetttgvlrlyqfaaagdlafpainvndsvtks
kfdnkygtrhslidginrgtdaliggkkvlicgygdvgkgcaeamkgqgarvsvteidpi
nalqammegfdvvtveeaigdadivvtatgnkdiimlehikamkdhailgnighfdneid
maglersgatrvnvkpqvdlwtfgdtgrsiivlsegrllnlgnatghpsfvmsnsfanqt
iaqielwtkndeydnevyrlpkhldekvarihvealgghltkltkeqaeylgvdvegpyk
pdhyry

  • Chain 'B':
    Sequence, based on SEQRES records:
    >3dhyB (B:)
mtgnlvtknsltpdvrngidfkiadlsladfgrkelriaehempglmslrreyaevqplk
garisgslhmtvqtavlietltalgaevrwascnifstqdhaaaavvvgphgtpdepkgv
pvfawkgetleeywwaaeqmltwpdpdkpanmilddggdatmlvlrgmqyekagvvppae
eddpaewkvflnllrtrfetdkdkwtkiaesvkgvteetttgvlrlyqfaaagdlafpai
nvndsvtkskfdnkygtrhslidginrgtdaliggkkvlicgygdvgkgcaeamkgqgar
vsvteidpinalqammegfdvvtveeaigdadivvtatgnkdiimlehikamkdhailgn
ighfdneidmaglersgatrvnvkpqvdlwtfgdtgrsiivlsegrllnlgnatghpsfv
msnsfanqtiaqielwtkndeydnevyrlpkhldekvarihvealgghltkltkeqaeyl
gvdvegpykpdhyry

    Sequence, based on observed residues (ATOM records):
    >3dhyB (B:)
ltpdvrngidfkiadlsladfgrkelriaehempglmslrreyaevqplkgarisgslhm
tvqtavlietltalgaevrwascnifstqdhaaaavvvgphgtpdepkgvpvfawkgetl
eeywwaaeqmltwpdpdkpanmilddggdatmlvlrgmqyekagvvppaeeddpaewkvf
lnllrtrfetdkdkwtkiaesvkgvteetttgvlrlyqfaaagdlafpainvndsvtksk
fdnkygtrhslidginrgtdaliggkkvlicgygdvgkgcaeamkgqgarvsvteidpin
alqammegfdvvtveeaigdadivvtatgnkdiimlehikamkdhailgnighfdneidm
aglersgatrvnvkpqvdlwtfgdtgrsiivlsegrllnlgnatghpsfvmsnsfanqti
aqielwtkndeydnevyrlpkhldekvarihvealgghltkltkeqaeylgvdvegpykp
dhyry

  • Chain 'C':
    Sequence, based on SEQRES records:
    >3dhyC (C:)
mtgnlvtknsltpdvrngidfkiadlsladfgrkelriaehempglmslrreyaevqplk
garisgslhmtvqtavlietltalgaevrwascnifstqdhaaaavvvgphgtpdepkgv
pvfawkgetleeywwaaeqmltwpdpdkpanmilddggdatmlvlrgmqyekagvvppae
eddpaewkvflnllrtrfetdkdkwtkiaesvkgvteetttgvlrlyqfaaagdlafpai
nvndsvtkskfdnkygtrhslidginrgtdaliggkkvlicgygdvgkgcaeamkgqgar
vsvteidpinalqammegfdvvtveeaigdadivvtatgnkdiimlehikamkdhailgn
ighfdneidmaglersgatrvnvkpqvdlwtfgdtgrsiivlsegrllnlgnatghpsfv
msnsfanqtiaqielwtkndeydnevyrlpkhldekvarihvealgghltkltkeqaeyl
gvdvegpykpdhyry

    Sequence, based on observed residues (ATOM records):
    >3dhyC (C:)
ltpdvrngidfkiadlsladfgrkelriaehempglmslrreyaevqplkgarisgslhm
tvqtavlietltalgaevrwascnifstqdhaaaavvvgphgtpdepkgvpvfawkgetl
eeywwaaeqmltwpdpdkpanmilddggdatmlvlrgmqyekagvvppaeeddpaewkvf
lnllrtrfetdkdkwtkiaesvkgvteetttgvlrlyqfaaagdlafpainvndsvtksk
fdnkygtrhslidginrgtdaliggkkvlicgygdvgkgcaeamkgqgarvsvteidpin
alqammegfdvvtveeaigdadivvtatgnkdiimlehikamkdhailgnighfdneidm
aglersgatrvnvkpqvdlwtfgdtgrsiivlsegrllnlgnatghpsfvmsnsfanqti
aqielwtkndeydnevyrlpkhldekvarihvealgghltkltkeqaeylgvdvegpykp
dhyry

  • Chain 'D':
    Sequence, based on SEQRES records:
    >3dhyD (D:)
mtgnlvtknsltpdvrngidfkiadlsladfgrkelriaehempglmslrreyaevqplk
garisgslhmtvqtavlietltalgaevrwascnifstqdhaaaavvvgphgtpdepkgv
pvfawkgetleeywwaaeqmltwpdpdkpanmilddggdatmlvlrgmqyekagvvppae
eddpaewkvflnllrtrfetdkdkwtkiaesvkgvteetttgvlrlyqfaaagdlafpai
nvndsvtkskfdnkygtrhslidginrgtdaliggkkvlicgygdvgkgcaeamkgqgar
vsvteidpinalqammegfdvvtveeaigdadivvtatgnkdiimlehikamkdhailgn
ighfdneidmaglersgatrvnvkpqvdlwtfgdtgrsiivlsegrllnlgnatghpsfv
msnsfanqtiaqielwtkndeydnevyrlpkhldekvarihvealgghltkltkeqaeyl
gvdvegpykpdhyry

    Sequence, based on observed residues (ATOM records):
    >3dhyD (D:)
ltpdvrngidfkiadlsladfgrkelriaehempglmslrreyaevqplkgarisgslhm
tvqtavlietltalgaevrwascnifstqdhaaaavvvgphgtpdepkgvpvfawkgetl
eeywwaaeqmltwpdpdkpanmilddggdatmlvlrgmqyekagvvppaeeddpaewkvf
lnllrtrfetdkdkwtkiaesvkgvteetttgvlrlyqfaaagdlafpainvndsvtksk
fdnkygtrhslidginrgtdaliggkkvlicgygdvgkgcaeamkgqgarvsvteidpin
alqammegfdvvtveeaigdadivvtatgnkdiimlehikamkdhailgnighfdneidm
aglersgatrvnvkpqvdlwtfgdtgrsiivlsegrllnlgnatghpsfvmsnsfanqti
aqielwtkndeydnevyrlpkhldekvarihvealgghltkltkeqaeylgvdvegpykp
dhyry