PDB entry 3dgr

View 3dgr on RCSB PDB site
Description: Crystal structure of human NAMPT complexed with ADP analogue
Class: transferase
Keywords: TRANSFERASE, NMPRTase, Visfatin, Adenosine 5'-(alpha, beta-methylene)diphosphate, Alternative splicing, Cytoplasm, Glycosyltransferase, Phosphoprotein, Polymorphism, Pyridine nucleotide biosynthesis
Deposited on 2008-06-15, released 2009-08-18
The last revision prior to the SCOPe 2.08 freeze date was dated 2017-10-25, with a file datestamp of 2017-10-20.
Experiment type: XRAY
Resolution: 2.1 Å
R-factor: N/A
AEROSPACI score: 0.29 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: Nicotinamide phosphoribosyltransferase
    Species: Homo sapiens [TaxId:9606]
    Gene: NAMPT, PBEF, PBEF1
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.08: d3dgra1, d3dgra2
  • Chain 'B':
    Compound: Nicotinamide phosphoribosyltransferase
    Species: Homo sapiens [TaxId:9606]
    Gene: NAMPT, PBEF, PBEF1
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.08: d3dgrb1, d3dgrb2
  • Heterogens: A12, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download) 
    >3dgrA (A:)
mnpaaeaefnillatdsykvthykqyppntskvysyfecrekktensklrkvkyeetvfy
glqyilnkylkgkvvtkekiqeakdvykehfqddvfnekgwnyilekydghlpieikavp
egfviprgnvlftventdpecywltnwietilvqswypitvatnsreqkkilakyllets
gnldgleyklhdfgyrgvssqetagigasahlvnfkgtdtvaglalikkyygtkdpvpgy
svpaaehstitawgkdhekdafehivtqfssvpvsvvsdsydiynacekiwgedlrhliv
srstqapliirpdsgnpldtvlkvleilgkkfpvtenskgykllppylrviqgdgvdint
lqeivegmkqkmwsieniafgsgggllqkltrdllncsfkcsyvvtnglginvfkdpvad
pnkrskkgrlslhrtpagnfvtleegkgdleeygqdllhtvfkngkvtksysfdeirkna
qlni

    Sequence, based on observed residues (ATOM records): (download) 
    >3dgrA (A:)
fnillatdsykvthykqyppntskvysyfecreyeetvfyglqyilnkylkgkvvtkeki
qeakdvykehfqddvfnekgwnyilekydghlpieikavpegfviprgnvlftventdpe
cywltnwietilvqswypitvatnsreqkkilakylletsgnldgleyklhdfgyrgvss
qetagigasahlvnfkgtdtvaglalikkyygtkdpvpgysvpaaehstitawgkdhekd
afehivtqfssvpvsvvsdsydiynacekiwgedlrhlivsrstqapliirpdsgnpldt
vlkvleilgkkfpvtenskgykllppylrviqgdgvdintlqeivegmkqkmwsieniaf
gsgggllqkltrdllncsfkcsyvvtnglginvfkdpvadpnkrskkgrlslhrtpagnf
vtleegkgdleeygqdllhtvfkngkvtksysfdeirknaqlni

  • Chain 'B':
    Sequence, based on SEQRES records: (download) 
    >3dgrB (B:)
mnpaaeaefnillatdsykvthykqyppntskvysyfecrekktensklrkvkyeetvfy
glqyilnkylkgkvvtkekiqeakdvykehfqddvfnekgwnyilekydghlpieikavp
egfviprgnvlftventdpecywltnwietilvqswypitvatnsreqkkilakyllets
gnldgleyklhdfgyrgvssqetagigasahlvnfkgtdtvaglalikkyygtkdpvpgy
svpaaehstitawgkdhekdafehivtqfssvpvsvvsdsydiynacekiwgedlrhliv
srstqapliirpdsgnpldtvlkvleilgkkfpvtenskgykllppylrviqgdgvdint
lqeivegmkqkmwsieniafgsgggllqkltrdllncsfkcsyvvtnglginvfkdpvad
pnkrskkgrlslhrtpagnfvtleegkgdleeygqdllhtvfkngkvtksysfdeirkna
qlni

    Sequence, based on observed residues (ATOM records): (download) 
    >3dgrB (B:)
fnillatdsykvthykqyppntskvysyfecreyeetvfyglqyilnkylkgkvvtkeki
qeakdvykehfqddvfnekgwnyilekydghlpieikavpegfviprgnvlftventdpe
cywltnwietilvqswypitvatnsreqkkilakylletsgnldgleyklhdfgyrgvss
qetagigasahlvnfkgtdtvaglalikkyygtkdpvpgysvpaaehstitawgkdhekd
afehivtqfssvpvsvvsdsydiynacekiwgedlrhlivsrstqapliirpdsgnpldt
vlkvleilgkkfpvtenskgykllppylrviqgdgvdintlqeivegmkqkmwsieniaf
gsgggllqkltrdllncsfkcsyvvtnglginvfkdpvadpnkrskkgrlslhrtpagnf
vtleegkgdleeygqdllhtvfkngkvtksysfdeirknaqlni