PDB entry 3df0

View 3df0 on RCSB PDB site
Description: Calcium-dependent complex between m-calpain and calpastatin
Class: hydrolase
Keywords: protease core domain, penta EF-hand domains, C2-like domain, inhibitor loop-out, Hydrolase, Membrane, Protease, Thiol protease, Phosphoprotein, Protease inhibitor, Thiol protease inhibitor
Deposited on 2008-06-11, released 2008-11-11
The last revision prior to the SCOPe 2.03 freeze date was dated 2011-07-13, with a file datestamp of 2011-05-08.
Experiment type: XRAY
Resolution: 2.95 Å
R-factor: 0.232
AEROSPACI score: 0.17 (click here for full SPACI score report)

Chains and heterogens:

• Chain 'A':
  Compound: Calpain-2 catalytic subunit
  Species: Rattus norvegicus [TaxId:10116]
  Gene: Capn2
  Database cross-references and differences (RAF-indexed):
  • Uniprot Q07009 (Start-699)
    • engineered (104)
    • expression tag (700)
• Chain 'B':
  Compound: Calpain small subunit 1
  Species: Rattus norvegicus [TaxId:10116]
  Gene: Capns1, Capn4, Css1
  Database cross-references and differences (RAF-indexed):
  • Uniprot Q64537 (Start-183)
  Domains in SCOPe 2.03: d3df0b_
• Chain 'C':
  Compound: Calpastatin
  Species: Rattus norvegicus [TaxId:10116]
  Gene: Cast
  Database cross-references and differences (RAF-indexed):
  • Uniprot P27321 (Start-85)
• Heterogens: CA

PDB Chain Sequences:

• Chain 'A':
  No sequence available.
  
  
• Chain 'B':
  Sequence, based on SEQRES records: (download)
  

  >3df0B (B:)
  mhysnieaneseeerqfrklfvqlagddmevsatelmnilnkvvtrhpdlktdgfgidtc
  rsmvavmdsdttgklgfeefkylwnnikkwqgiykrfdtdrsgtigsnelpgafeaagfh
  lnqhiysmiirrysdetgnmdfdnfisclvrldamfrafrsldkngtgqiqvniqewlql
  tmys
  

  
  Sequence, based on observed residues (ATOM records): (download)
  

  >3df0B (B:)
  seeerqfrklfvqlagddmevsatelmnilnkvvtrhpdlktdgfgidtcrsmvavmdsd
  ttgklgfeefkylwnnikkwqgiykrfdtdrsgtigsnelpgafeaagfhlnqhiysmii
  rrysdetgnmdfdnfisclvrldamfrafrsldkngtgqiqvniqewlqltmys
  

  
  
• Chain 'C':
  No sequence available.