PDB entry 3ddu

View 3ddu on RCSB PDB site
Description: Prolyl Oligopeptidase with GSK552
Class: hydrolase
Keywords: POP, Prolyl Oligopeptidase, endopeptidase, HYDROLASE
Deposited on 2008-06-06, released 2008-08-19
The last revision prior to the SCOPe 2.03 freeze date was dated 2011-07-13, with a file datestamp of 2011-05-25.
Experiment type: XRAY
Resolution: 1.56 Å
R-factor: 0.149
AEROSPACI score: 0.64 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: prolyl endopeptidase
    Species: Homo sapiens [TaxId:9606]
    Gene: PREP, PEP
    Database cross-references and differences (RAF-indexed):
    • Uniprot P48147 (0-708)
      • engineered (305)
      • engineered (317)
      • engineered (358)
      • engineered (372)
      • engineered (665)
    Domains in SCOPe 2.03: d3ddua1, d3ddua2
  • Heterogens: ACT, 552, GOL, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download) 
    >3dduA (A:)
lsfqypdvyrdetavqdyhghkicdpyawledpdseqtkafveaqnkitvpfleqcpirg
lykermtelydypkyschfkkgkryfyfyntglqnqrvlyvqdslegearvfldpnilsd
dgtvalrgyafsedgeyfayglsasgsdwvtikfmkvdgakelpdvlervkfscmawthd
gkgmfynsypqqdgksdgtetstnlhqklyyhvlgtdqsedilcaefpdepkwmggaels
ddgryvllsiregcdpvnrlwycdlqqessgiagilkwvklidnfegeydyvtnegtvft
fktnrhspnyrvinidftdpeeskwkvlvpehekdvlewiacvrsnflvlcylhdvkntl
qlhdlttgallkifpldvgsivgysgqkkdteifyqftsflspgiiyhcdltkeeleprv
frevtvkgidasdyqtvqifypskdgtkipmfivhkkgikldgshpaflygyggfnisit
pnysvsrlifvrhmggilavanirgggeygetwhkggilankqncfddfqcaaeylikeg
ytspkrltinggsnggllvaacanqrpdlfgcviaqvgvmdmlkfhkytighawttdygc
sdskqhfewlvkysplhnvklpeaddiqypsmllltadhddrvvplhslkfiatlqyivg
rsrkqnnpllihvdtkaghgagkptakvieevsdmfafiarclnvdwip

    Sequence, based on observed residues (ATOM records): (download) 
    >3dduA (A:)
lsfqypdvyrdetavqdyhghkicdpyawledpdseqtkafveaqnkitvpfleqcpirg
lykermtelydypkyschfkkgkryfyfyntglqnqrvlyvqdslegearvfldpnilsd
dgtvalrgyafsedgeyfayglsasgsdwvtikfmkvdgakelpdvlervkfscmawthd
gkgmfynsypqqdgksdgtetstnlhqklyyhvlgtdqsedilcaefpdepkwmggaels
ddgryvllsiregcdpvnrlwycdlqqessgiagilkwvklidnfegeydyvtnegtvft
fktnrhspnyrvinidftdpeeskwkvlvpehekdvlewiacvrsnflvlcylhdvkntl
qlhdlttgallkifpldvgsivgysgqkkdteifyqftsflspgiiyhcdltkeeleprv
frevvkidasdyqtvqifypskdgtkipmfivhkkgikldgshpaflygyggfnisitpn
ysvsrlifvrhmggilavanirgggeygetwhkggilankqncfddfqcaaeylikegyt
spkrltinggsnggllvaacanqrpdlfgcviaqvgvmdmlkfhkytighawttdygcsd
skqhfewlvkysplhnvklpeaddiqypsmllltadhddrvvplhslkfiatlqyivgrs
rkqnnpllihvdtkaghgagkptakvieevsdmfafiarclnvdwip