PDB entry 3ddq
View 3ddq on RCSB PDB site
Description: Structure of phosphorylated Thr160 CDK2/cyclin A in complex with the inhibitor roscovitine
Class: transferase/cell cycle
Keywords: Ser/Thr protein kinase; transferase; phosphorylation; cell cycle, ATP-binding, Cell cycle, Cell division, Kinase, Mitosis, Nucleotide-binding, Phosphoprotein, Polymorphism, Serine/threonine-protein kinase, Cyclin, Cytoplasm, Nucleus, TRANSFERASE/CELL CYCLE COMPLEX
Deposited on
2008-06-06, released
2008-07-22
The last revision prior to the SCOP 1.75 freeze date was dated
2008-10-14, with a file datestamp of
2008-10-10.
Experiment type: XRAY
Resolution: 1.8 Å
R-factor: 0.195
AEROSPACI score: 0.6
(click here for full SPACI score report)
Chains and heterogens:
- Chain 'A':
Compound: Cell division protein kinase 2
Species: Homo sapiens [TaxId:9606]
Gene: CDK2
Database cross-references and differences (RAF-indexed):
- Chain 'B':
Compound: Cyclin-A2
Species: Bos taurus [TaxId:9913]
Gene: CCNA2, CCNA
Database cross-references and differences (RAF-indexed):
Domains in SCOP 1.75: d3ddqb1, d3ddqb2 - Chain 'C':
Compound: Cell division protein kinase 2
Species: Homo sapiens [TaxId:9606]
Gene: CDK2
Database cross-references and differences (RAF-indexed):
- Chain 'D':
Compound: Cyclin-A2
Species: Bos taurus [TaxId:9913]
Gene: CCNA2, CCNA
Database cross-references and differences (RAF-indexed):
Domains in SCOP 1.75: d3ddqd1, d3ddqd2 - Heterogens: RRC, SGM, HOH
PDB Chain Sequences:
- Chain 'A':
No sequence available.
- Chain 'B':
Sequence, based on SEQRES records: (download)
>3ddqB (B:)
svnevpdyhedihtylremevkckpkvgymkkqpditnsmrailvdwlvevgeeyklqne
tlhlavnyidrflssmsvlrgklqlvgtaamllaskfeeiyppevaefvyitddtytkkq
vlrmehlvlkvlafdlaaptinqfltqyflhqqpanckveslamflgelslidadpylky
lpsviaaaafhlalytvtgqswpeslvqktgytletlkpclldlhqtylrapqhaqqsir
ekyknskyhgvsllnppetlnvhhhhhhh
Sequence, based on observed residues (ATOM records): (download)
>3ddqB (B:)
svnevpdyhedihtylremevkckpkvgymkkqpditnsmrailvdwlvevgeeyklqne
tlhlavnyidrflssmsvlrgklqlvgtaamllaskfeeiyppevaefvyitddtytkkq
vlrmehlvlkvlafdlaaptinqfltqyflhqqpanckveslamflgelslidadpylky
lpsviaaaafhlalytvtgqswpeslvqktgytletlkpclldlhqtylrapqhaqqsir
ekyknskyhgvsllnppetlnv
- Chain 'C':
No sequence available.
- Chain 'D':
Sequence; same for both SEQRES and ATOM records: (download)
>3ddqD (D:)
svnevpdyhedihtylremevkckpkvgymkkqpditnsmrailvdwlvevgeeyklqne
tlhlavnyidrflssmsvlrgklqlvgtaamllaskfeeiyppevaefvyitddtytkkq
vlrmehlvlkvlafdlaaptinqfltqyflhqqpanckveslamflgelslidadpylky
lpsviaaaafhlalytvtgqswpeslvqktgytletlkpclldlhqtylrapqhaqqsir
ekyknskyhgvsllnppetlnvhhhhhhh