PDB entry 3dd1

View 3dd1 on RCSB PDB site
Description: Crystal structure of glycogen phophorylase complexed with an anthranilimide based inhibitor GSK254
Class: transferase
Keywords: Glycogen Phosphorylase HLGP, Diabetes, Allosteric enzyme, Carbohydrate metabolism, Disease mutation, Glycogen metabolism, Glycogen storage disease, Glycosyltransferase, Nucleotide-binding, Phosphoprotein, Pyridoxal phosphate, Transferase
Deposited on 2008-06-04, released 2009-04-21
The last revision prior to the SCOPe 2.01 freeze date was dated 2011-07-13, with a file datestamp of 2011-05-25.
Experiment type: XRAY
Resolution: 2.57 Å
R-factor: 0.169
AEROSPACI score: 0.36 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: Glycogen phosphorylase, liver form
    Species: Homo sapiens [TaxId:9606]
    Gene: PYGL
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.01: d3dd1a_
  • Chain 'B':
    Compound: Glycogen phosphorylase, liver form
    Species: Homo sapiens [TaxId:9606]
    Gene: PYGL
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.01: d3dd1b_
  • Heterogens: NBG, PLP, CFF, 25D, MES, MPD, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download) 
    >3dd1A (A:)
ggakpltdqekrrqisirgivgvenvaelkksfnrhlhftlvkdrnvattrdyyfalaht
vrdhlvgrwirtqqhyydkcpkrvyylslefymgrtlqntminlglqnacdeaiyqlgld
ieeleeieedaglgngglgrlaacfldsmatlglaaygygiryeygifnqkirdgwqvee
addwlrygnpweksrpefmlpvhfygkvehtntgtkwidtqvvlalpydtpvpgymnntv
ntmrlwsarapndfnlrdfnvgdyiqavldrnlaenisrvlypndnffegkelrlkqeyf
vvaatlqdiirrfkaskfgstrgagtvfdafpdqvaiqlndthpalaipelmrifvdiek
lpwskaweltqktfaytnhtvlpealerwpvdlvekllprhleiiyeinqkhldrivalf
pkdvdrlrrmslieeegskrinmahlcivgshavngvakihsdivktkvfkdfselepdk
fqnktngitprrwlllcnpglaeliaekigedyvkdlsqltklhsflgddvflrelakvk
qenklkfsqfleteykvkinpssmfdvqvkriheykrqllnclhvitmynrikkdpkklf
vprtviiggkaapgyhmakmiiklitsvadvvnndpmvgsklkviflenyrvslaekvip
atdlseqistagteasgtgnmkfmlngaltigtmdganvemaeeageenlfifgmriddv
aaldkkgyeakeyyealpelklvidqidngffspkqpdlfkdiinmlfyhdrfkvfadye
ayvkcqdkvsqlymnpkawntmvlkniaasgkfssdrtikeyaqniwnvepsdlkislsn
esnkvngn

    Sequence, based on observed residues (ATOM records): (download) 
    >3dd1A (A:)
qisirgivgvenvaelkksfnrhlhftlvkdrnvattrdyyfalahtvrdhlvgrwirtq
qhyydkcpkrvyylslefymgrtlqntminlglqnacdeaiyqlgldieeleeieedagl
gngglgrlaacfldsmatlglaaygygiryeygifnqkirdgwqveeaddwlrygnpwek
srpefmlpvhfygkvehtntgtkwidtqvvlalpydtpvpgymnntvntmrlwsarapnd
gdyiqavldrnlaenisrvlypndnffegkelrlkqeyfvvaatlqdiirrfkaskfgst
rgagtvfdafpdqvaiqlndthpalaipelmrifvdieklpwskaweltqktfaytnhtv
lpealerwpvdlvekllprhleiiyeinqkhldrivalfpkdvdrlrrmslieeegskri
nmahlcivgshavngvakihsdivktkvfkdfselepdkfqnktngitprrwlllcnpgl
aeliaekigedyvkdlsqltklhsflgddvflrelakvkqenklkfsqfleteykvkinp
ssmfdvqvkriheykrqllnclhvitmynrikkdpkklfvprtviiggkaapgyhmakmi
iklitsvadvvnndpmvgsklkviflenyrvslaekvipatdlseqistagteasgtgnm
kfmlngaltigtmdganvemaeeageenlfifgmriddvaaldkkgyeakeyyealpelk
lvidqidngffspkqpdlfkdiinmlfyhdrfkvfadyeayvkcqdkvsqlymnpkawnt
mvlkniaasgkfssdrtikeyaqniwnveps

  • Chain 'B':
    Sequence, based on SEQRES records: (download) 
    >3dd1B (B:)
ggakpltdqekrrqisirgivgvenvaelkksfnrhlhftlvkdrnvattrdyyfalaht
vrdhlvgrwirtqqhyydkcpkrvyylslefymgrtlqntminlglqnacdeaiyqlgld
ieeleeieedaglgngglgrlaacfldsmatlglaaygygiryeygifnqkirdgwqvee
addwlrygnpweksrpefmlpvhfygkvehtntgtkwidtqvvlalpydtpvpgymnntv
ntmrlwsarapndfnlrdfnvgdyiqavldrnlaenisrvlypndnffegkelrlkqeyf
vvaatlqdiirrfkaskfgstrgagtvfdafpdqvaiqlndthpalaipelmrifvdiek
lpwskaweltqktfaytnhtvlpealerwpvdlvekllprhleiiyeinqkhldrivalf
pkdvdrlrrmslieeegskrinmahlcivgshavngvakihsdivktkvfkdfselepdk
fqnktngitprrwlllcnpglaeliaekigedyvkdlsqltklhsflgddvflrelakvk
qenklkfsqfleteykvkinpssmfdvqvkriheykrqllnclhvitmynrikkdpkklf
vprtviiggkaapgyhmakmiiklitsvadvvnndpmvgsklkviflenyrvslaekvip
atdlseqistagteasgtgnmkfmlngaltigtmdganvemaeeageenlfifgmriddv
aaldkkgyeakeyyealpelklvidqidngffspkqpdlfkdiinmlfyhdrfkvfadye
ayvkcqdkvsqlymnpkawntmvlkniaasgkfssdrtikeyaqniwnvepsdlkislsn
esnkvngn

    Sequence, based on observed residues (ATOM records): (download) 
    >3dd1B (B:)
nvaelkksfnrhlhftlvkdrnvattrdyyfalahtvrdhlvgrwirtqqhyydkcpkrv
yylslefymgrtlqntminlglqnacdeaiyqlgldieeleeieedaglgngglgrlaac
fldsmatlglaaygygiryeygifnqkirdgwqveeaddwlrygnpweksrpefmlpvhf
ygkvehtntgtkwidtqvvlalpydtpvpgymnntvntmrlwsarapndfnlrdfnvgdy
iqavldrnlaenisrvlypndnffegkelrlkqeyfvvaatlqdiirrfkaskfgstgtv
fdafpdqvaiqlndthpalaipelmrifvdieklpwskaweltqktfaytnhtvlpeale
rwpvdlvekllprhleiiyeinqkhldrivalfpkdvdrlrrmslieeegskrinmahlc
ivgshavngvakihsdivktkvfkdfselepdkfqnktngitprrwlllcnpglaeliae
kigedyvkdlsqltklhsflgddvflrelakvkqenklkfsqfleteykvkinpssmfdv
qvkriheykrqllnclhvitmynrikkdpkklfvprtviiggkaapgyhmakmiiklits
vadvvnndpmvgsklkviflenyrvslaekvipatdlseqistagteasgtgnmkfmlng
altigtmdganvemaeeageenlfifgmriddvaaldkkgyeakeyyealpelklvidqi
dngffspkqpdlfkdiinmlfyhdrfkvfadyeayvkcqdkvsqlymnpkawntmvlkni
aasgkfssdrtikeyaqniwnveps