PDB entry 3dd0
View 3dd0 on RCSB PDB site
Description: Use of Carbonic Anhydrase II, IX Active-Site Mimic, for the Purpose of Screening Inhibitors for Possible Anti-Cancer Properties
Class: lyase
Keywords: Carbonic anhydrase II complex, CAIX mimic inhibitors, Acetylation, Cytoplasm, Disease mutation, Lyase, Metal-binding, Polymorphism, Zinc
Deposited on
2008-06-04, released
2009-03-03
The last revision prior to the SCOPe 2.06 freeze date was dated
2009-07-07, with a file datestamp of
2009-07-02.
Experiment type: XRAY
Resolution: 1.48 Å
R-factor: 0.154
AEROSPACI score: 0.67
(click here for full SPACI score report)
Chains and heterogens:
- Chain 'A':
Compound: Carbonic anhydrase 2
Species: Homo sapiens [TaxId:9606]
Gene: CA2
Database cross-references and differences (RAF-indexed):
Domains in SCOPe 2.06: d3dd0a_ - Heterogens: ZN, EZL, HOH
PDB Chain Sequences:
- Chain 'A':
Sequence, based on SEQRES records: (download)
>3dd0A (A:)
mshhwgygkhngpehwhkdfpiakgerqspvdidthtakydpslkplsvsydqatslril
nnghafnvefddsqdkavlkggpldgtyrliqfhfhwgsldgqgsehtvdkkkyaaelhl
vhwntkygdfgkavqqpdglavlgiflkvgsakpglqkvvdvldsiktkgksadftnfdp
rgllpesldywtypgslttppllecvtwivlkepisvsseqvlkfrklnfngegepeelm
vdnwrpaqplknrqikasfk
Sequence, based on observed residues (ATOM records): (download)
>3dd0A (A:)
hhwgygkhngpehwhkdfpiakgerqspvdidthtakydpslkplsvsydqatslrilnn
ghafnvefddsqdkavlkggpldgtyrliqfhfhwgsldgqgsehtvdkkkyaaelhlvh
wntkygdfgkavqqpdglavlgiflkvgsakpglqkvvdvldsiktkgksadftnfdprg
llpesldywtypgslttppllecvtwivlkepisvsseqvlkfrklnfngegepeelmvd
nwrpaqplknrqikasfk