PDB entry 3dcv

View 3dcv on RCSB PDB site
Description: Crystal structure of human Pim1 kinase complexed with 4-(4-hydroxy-3-methyl-phenyl)-6-phenylpyrimidin-2(1H)-one
Class: transferase
Keywords: Ser/Thr protein kinase, nucleotide-binding, phsphorylation, ATP-binding, cancer, oncogene, Alternative initiation, Cytoplasm, Manganese, Membrane, Metal-binding, Nucleus, Phosphoprotein, Polymorphism, Proto-oncogene, Serine/threonine-protein kinase, Transferase
Deposited on 2008-06-04, released 2008-08-19
The last revision prior to the SCOPe 2.05 freeze date was dated 2009-02-24, with a file datestamp of 2009-02-03.
Experiment type: XRAY
Resolution: 2.7 Å
R-factor: 0.182
AEROSPACI score: 0.31 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: Proto-oncogene serine/threonine-protein kinase Pim-1
    Species: Homo sapiens [TaxId:9606]
    Gene: PIM1
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.05: d3dcva_
  • Heterogens: 55E, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download) 
    >3dcvA (A:)
mahhhhhhlevlfqgpllskinslahlraapcndlhatklapgkekeplesqyqvgpllg
sggfgsvysgirvsdnlpvaikhvekdrisdwgelpngtrvpmevvllkkvssgfsgvir
lldwferpdsfvlilerpepvqdlfdfitergalqeelarsffwqvleavrhchncgvlh
rdikdenilidlnrgelklidfgsgallkdtvytdfdgtrvysppewiryhryhgrsaav
wslgillydmvcgdipfehdeeiirgqvffrqrvssecqhlirwclalrpsdrptfeeiq
nhpwmqdvllpqetaeihlhslspgpsk

    Sequence, based on observed residues (ATOM records): (download) 
    >3dcvA (A:)
eplesqyqvgpllgsggfgsvysgirvsdnlpvaikhvekdrisdwgelpngtrvpmevv
llkkvssgfsgvirlldwferpdsfvlilerpepvqdlfdfitergalqeelarsffwqv
leavrhchncgvlhrdikdenilidlnrgelklidfgsgallkdtvytdfdgtrvysppe
wiryhryhgrsaavwslgillydmvcgdipfehdeeiirgqvffrqrvssecqhlirwcl
alrpsdrptfeeiqnhpwmqdvllpqetaeihlh