PDB entry 3dc1

View 3dc1 on RCSB PDB site
Description: Crystal structure of kynurenine aminotransferase II complex with alpha-ketoglutarate
Class: transferase
Keywords: ALPHA & BETA PROTEIN, PLP-DEPENDENT TRANSFERASE, AMINOTRANSFERASE, MULTIFUNCTIONAL ENZYME, PYRIDOXAL PHOSPHATE, Mitochondrion, Transferase, Transit peptide
Deposited on 2008-06-03, released 2008-07-29
The last revision prior to the SCOPe 2.01 freeze date was dated 2011-07-13, with a file datestamp of 2011-05-25.
Experiment type: XRAY
Resolution: 2.5 Å
R-factor: 0.217
AEROSPACI score: 0.29 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: Kynurenine/alpha-aminoadipate aminotransferase mitochondrial
    Species: Homo sapiens [TaxId:9606]
    Gene: AADAT, KAT2
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.01: d3dc1a_
  • Chain 'B':
    Compound: Kynurenine/alpha-aminoadipate aminotransferase mitochondrial
    Species: Homo sapiens [TaxId:9606]
    Gene: AADAT, KAT2
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.01: d3dc1b_
  • Chain 'C':
    Compound: Kynurenine/alpha-aminoadipate aminotransferase mitochondrial
    Species: Homo sapiens [TaxId:9606]
    Gene: AADAT, KAT2
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.01: d3dc1c_
  • Chain 'D':
    Compound: Kynurenine/alpha-aminoadipate aminotransferase mitochondrial
    Species: Homo sapiens [TaxId:9606]
    Gene: AADAT, KAT2
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.01: d3dc1d_
  • Heterogens: AKG, GOL, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download) 
    >3dc1A (A:)
mnyarfitaasaarnpspirtmtdilsrgpksmislagglpnpnmfpfktavitvengkt
iqfgeemmkralqyspsagipellswlkqlqiklhnpptihyppsqgqmdlcvtsgsqqg
lckvfemiinpgdnvlldepaysgtlqslhplgcniinvasdesgivpdslrdilsrwkp
edaknpqkntpkflytvpngnnptgnsltserkkeiyelarkydfliieddpyyflqfnk
frvptflsmdvdgrviradsfskiissglrigfltgpkpliervilhiqvstlhpstfnq
lmisqllhewgeegfmahvdrvidfysnqkdailaaadkwltglaewhvpaagmflwikv
kgindvkelieekavkmgvlmlpgnafyvdssapspylrasfssaspeqmdvafqvlaql
ikesl

    Sequence, based on observed residues (ATOM records): (download) 
    >3dc1A (A:)
mnyarfitaasaarnpspgpksmislagglpnpnmfpfktavitvengktiqfgeemmkr
alqyspsagipellswlkqlqiklhnpptihyppsqgqmdlcvtsgsqqglckvfemiin
pgdnvlldepaysgtlqslhplgcniinvasdesgivpdslrdilsrwkpedaknpqknt
pkflytvpngnnptgnsltserkkeiyelarkydfliieddpyyflqfnkfrvptflsmd
vdgrviradsfskiissglrigfltgpkpliervilhiqvstlhpstfnqlmisqllhew
geegfmahvdrvidfysnqkdailaaadkwltglaewhvpaagmflwikvkgindvkeli
eekavkmgvlmlpgnafyvdssapspylrasfssaspeqmdvafqvlaqlikesl

  • Chain 'B':
    Sequence, based on SEQRES records: (download) 
    >3dc1B (B:)
mnyarfitaasaarnpspirtmtdilsrgpksmislagglpnpnmfpfktavitvengkt
iqfgeemmkralqyspsagipellswlkqlqiklhnpptihyppsqgqmdlcvtsgsqqg
lckvfemiinpgdnvlldepaysgtlqslhplgcniinvasdesgivpdslrdilsrwkp
edaknpqkntpkflytvpngnnptgnsltserkkeiyelarkydfliieddpyyflqfnk
frvptflsmdvdgrviradsfskiissglrigfltgpkpliervilhiqvstlhpstfnq
lmisqllhewgeegfmahvdrvidfysnqkdailaaadkwltglaewhvpaagmflwikv
kgindvkelieekavkmgvlmlpgnafyvdssapspylrasfssaspeqmdvafqvlaql
ikesl

    Sequence, based on observed residues (ATOM records): (download) 
    >3dc1B (B:)
mnyarfitaasaarnpspirgpksmislagglpnpnmfpfktavitvengktiqfgeemm
kralqyspsagipellswlkqlqiklhnpptihyppsqgqmdlcvtsgsqqglckvfemi
inpgdnvlldepaysgtlqslhplgcniinvasdesgivpdslrdilsrwkpedaknpqk
ntpkflytvpngnnptgnsltserkkeiyelarkydfliieddpyyflqfnkfrvptfls
mdvdgrviradsfskiissglrigfltgpkpliervilhiqvstlhpstfnqlmisqllh
ewgeegfmahvdrvidfysnqkdailaaadkwltglaewhvpaagmflwikvkgindvke
lieekavkmgvlmlpgnafyvdssapspylrasfssaspeqmdvafqvlaqlikesl

  • Chain 'C':
    Sequence; same for both SEQRES and ATOM records: (download) 
    >3dc1C (C:)
mnyarfitaasaarnpspirtmtdilsrgpksmislagglpnpnmfpfktavitvengkt
iqfgeemmkralqyspsagipellswlkqlqiklhnpptihyppsqgqmdlcvtsgsqqg
lckvfemiinpgdnvlldepaysgtlqslhplgcniinvasdesgivpdslrdilsrwkp
edaknpqkntpkflytvpngnnptgnsltserkkeiyelarkydfliieddpyyflqfnk
frvptflsmdvdgrviradsfskiissglrigfltgpkpliervilhiqvstlhpstfnq
lmisqllhewgeegfmahvdrvidfysnqkdailaaadkwltglaewhvpaagmflwikv
kgindvkelieekavkmgvlmlpgnafyvdssapspylrasfssaspeqmdvafqvlaql
ikesl

  • Chain 'D':
    Sequence, based on SEQRES records: (download) 
    >3dc1D (D:)
mnyarfitaasaarnpspirtmtdilsrgpksmislagglpnpnmfpfktavitvengkt
iqfgeemmkralqyspsagipellswlkqlqiklhnpptihyppsqgqmdlcvtsgsqqg
lckvfemiinpgdnvlldepaysgtlqslhplgcniinvasdesgivpdslrdilsrwkp
edaknpqkntpkflytvpngnnptgnsltserkkeiyelarkydfliieddpyyflqfnk
frvptflsmdvdgrviradsfskiissglrigfltgpkpliervilhiqvstlhpstfnq
lmisqllhewgeegfmahvdrvidfysnqkdailaaadkwltglaewhvpaagmflwikv
kgindvkelieekavkmgvlmlpgnafyvdssapspylrasfssaspeqmdvafqvlaql
ikesl

    Sequence, based on observed residues (ATOM records): (download) 
    >3dc1D (D:)
mnyarfitaasaarnpspirrgpksmislagglpnpnmfpfktavitvengktiqfgeem
mkralqyspsagipellswlkqlqiklhnpptihyppsqgqmdlcvtsgsqqglckvfem
iinpgdnvlldepaysgtlqslhplgcniinvasdesgivpdslrdilsrwkpedaknpq
kntpkflytvpngnnptgnsltserkkeiyelarkydfliieddpyyflqfnkfrvptfl
smdvdgrviradsfskiissglrigfltgpkpliervilhiqvstlhpstfnqlmisqll
hewgeegfmahvdrvidfysnqkdailaaadkwltglaewhvpaagmflwikvkgindvk
elieekavkmgvlmlpgnafyvdssapspylrasfssaspeqmdvafqvlaqlikesl