PDB entry 3dbc

View 3dbc on RCSB PDB site
Description: crystal structure of an activated (thr->asp) polo-like kinase 1 (plk1) catalytic domain in complex with compound 257
Deposited on 2008-05-31, released 2008-10-07
The last revision was dated 2021-10-20, with a file datestamp of 2021-10-15.
Experiment type: XRAY
Resolution: 3.35 Å
R-factor: 0.245
AEROSPACI score: 0.15 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: Polo-like kinase 1
    Species: Danio rerio [TaxId:7955]
    Gene: PLK1
    Database cross-references and differences (RAF-indexed):
    • Uniprot Q4KMI8 (5-316)
      • expression tag (0-4)
      • engineered mutation (200)
  • Heterogens: 2FR

PDB Chain Sequences:
This PDB entry is not classified in SCOPe 2.08, so the chain sequences below are not included in the ASTRAL sequence sets.

  • Chain 'A':
    Sequence, based on SEQRES records:
    >3dbcA (A:)
gplgsmsaaiakpsakpsahvdpksaplkeipdvlvdprtmkrymrgrflgkggfakcye
itdmdtkevfagkvvpksmllkphqkekmsteiaihksldnphvvgfhgffedddfvyvv
leicrrrsllelhkrrkavtepearyfmrqtiqgvqylhnnrvihrdlklgnlflnddmd
vkigdfglatkiefdgerkkdlcgtpnyiapevlckkghsfevdiwslgcilytllvgkp
pfetsclketyirikkneysvprhinpvasalirrmlhadptlrpsvaelltdefftsgy
apmrlptscltvpprfs

    Sequence, based on observed residues (ATOM records):
    >3dbcA (A:)
keipdvlvdprtmkrymrgrflgkggfakcyeitdmdtkevfagkvvpksmllkphqkek
msteiaihksldnphvvgfhgffedddfvyvvleicrrrsllelhkrrkavtepearyfm
rqtiqgvqylhnnrvihrdlklgnlflnddmdvkigdfglatkihsfevdiwslgcilyt
llvgkppfetsclketyirikkneysvprhinpvasalirrmlhadptlrpsvaelltde
fftsgyapmrlptscltvppr