PDB entry 3d87

View 3d87 on RCSB PDB site
Description: Crystal structure of Interleukin-23
Class: cytokine
Keywords: Interleukin-23, FAB, CYTOKINE
Deposited on 2008-05-22, released 2008-09-02
The last revision prior to the SCOPe 2.08 freeze date was dated 2020-07-29, with a file datestamp of 2020-07-04.
Experiment type: XRAY
Resolution: 2.9 Å
R-factor: N/A
AEROSPACI score: 0.12 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: Interleukin-23 subunit p19
    Species: Homo sapiens [TaxId:9606]
    Gene: IL23A, SGRF, UNQ2498/PRO5798
    Database cross-references and differences (RAF-indexed):
  • Chain 'B':
    Compound: Interleukin-12 subunit p40
    Species: Homo sapiens [TaxId:9606]
    Gene: IL12B, NKSF2
    Database cross-references and differences (RAF-indexed):
    • Uniprot P29460 (0-305)
      • engineered (199)
    Domains in SCOPe 2.08: d3d87b1, d3d87b2, d3d87b3
  • Chain 'C':
    Compound: Interleukin-23 subunit p19
    Species: Homo sapiens [TaxId:9606]
    Gene: IL23A, SGRF, UNQ2498/PRO5798
    Database cross-references and differences (RAF-indexed):
  • Chain 'D':
    Compound: Interleukin-12 subunit p40
    Species: Homo sapiens [TaxId:9606]
    Gene: IL12B, NKSF2
    Database cross-references and differences (RAF-indexed):
    • Uniprot P29460 (0-End)
      • engineered (199)
    Domains in SCOPe 2.08: d3d87d1, d3d87d2, d3d87d3
  • Heterogens: PO4, K, MAN

PDB Chain Sequences:

  • Chain 'A':
    No sequence available.

  • Chain 'B':
    Sequence, based on SEQRES records: (download) 
    >3d87B (B:)
iwelkkdvyvveldwypdapgemvvltcdtpeedgitwtldqssevlgsgktltiqvkef
gdagqytchkggevlshsllllhkkedgiwstdilkdqkepknktflrceaknysgrftc
wwlttistdltfsvkssrgssdpqgvtcgaatlsaervrgdnkeyeysvecqedsacpaa
eeslpievmvdavhklkyeqytssffirdiikpdppknlqlkplknsrqvevsweypdtw
stphsyfsltfcvqvqgkskrekkdrvftdktsatvicrknasisvraqdryyssswsew
asvpcs

    Sequence, based on observed residues (ATOM records): (download) 
    >3d87B (B:)
iwelkkdvyvveldwypdapgemvvltcdtpeedgitwtldqssevlgsgktltiqvkef
gdagqytchkggevlshsllllhkkedgiwstdilkdqkepknktflrceaknysgrftc
wwlttistdltfsvkssrgssdpqgvtcgaatlsaervrgdnkeyeysvecqedsacpaa
eeslpievmvdavhklkyeqytssffirdiikpdppknlqlkplknsrqvevsweypdtw
stphsyfsltfcvqvqdrvftdktsatvicrknasisvraqdryyssswsewasvpcs

  • Chain 'C':
    No sequence available.

  • Chain 'D':
    Sequence, based on SEQRES records: (download) 
    >3d87D (D:)
iwelkkdvyvveldwypdapgemvvltcdtpeedgitwtldqssevlgsgktltiqvkef
gdagqytchkggevlshsllllhkkedgiwstdilkdqkepknktflrceaknysgrftc
wwlttistdltfsvkssrgssdpqgvtcgaatlsaervrgdnkeyeysvecqedsacpaa
eeslpievmvdavhklkyeqytssffirdiikpdppknlqlkplknsrqvevsweypdtw
stphsyfsltfcvqvqgkskrekkdrvftdktsatvicrknasisvraqdryyssswsew
asvpcs

    Sequence, based on observed residues (ATOM records): (download) 
    >3d87D (D:)
iwelkkdvyvveldwypdapgemvvltcdtpeedgitwtldqssevlgsgktltiqvkef
gdagqytchkggevlshsllllhkkedgiwstdilkdqkepknktflrceaknysgrftc
wwlttistdltfsvkssrgssdpqgvtcgaatlsaervrgdnkeyeysvecqedsacpaa
eeslpievmvdavhklkyeqytssffirdiikpdppknlqlkplknsrqvevsweypdtw
stphsyfsltfcvqvdrvftdktsatvicrknasisvraqdryyssswsewasvpc