PDB entry 3d7u

View 3d7u on RCSB PDB site
Description: Structural basis for the recognition of c-Src by its inactivator Csk
Class: transferase
Keywords: Csk c-Src Tyrosine kinase, ATP-binding, Kinase, Membrane, Nucleotide-binding, Phosphoprotein, SH2 domain, SH3 domain, Transferase, Tyrosine-protein kinase, Lipoprotein, Myristate, Proto-oncogene
Deposited on 2008-05-21, released 2008-08-05
The last revision prior to the SCOPe 2.08 freeze date was dated 2013-09-18, with a file datestamp of 2013-09-13.
Experiment type: XRAY
Resolution: 4.11 Å
R-factor: 0.294
AEROSPACI score: 0.07 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: Tyrosine-protein kinase CSK
    Species: Homo sapiens [TaxId:9606]
    Gene: CSK
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.08: d3d7ua1
  • Chain 'B':
    Compound: Proto-oncogene tyrosine-protein kinase Src
    Species: Gallus gallus [TaxId:9031]
    Gene: SRC
    Database cross-references and differences (RAF-indexed):
    • Uniprot P00523 (3-266)
      • expression tag (0-2)
      • expression tag (267-276)
  • Chain 'C':
    Compound: Tyrosine-protein kinase CSK
    Species: Homo sapiens [TaxId:9606]
    Gene: CSK
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.08: d3d7uc1
  • Chain 'D':
    Compound: Proto-oncogene tyrosine-protein kinase Src
    Species: Gallus gallus [TaxId:9031]
    Gene: SRC
    Database cross-references and differences (RAF-indexed):
    • Uniprot P00523 (3-266)
      • expression tag (0-2)

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download) 
    >3d7uA (A:)
walnmkelkllqtigkgefgdvmlgdyrgnkvavkcikndataqaflaeasvmtqlrhsn
lvqllgviveekgglyivteymakgslvdylrsrgrsvlggdcllkfsldvceameyleg
nnfvhrdlaarnvlvsednvakvsdfgltkeasstqdtgklpvkwtapealrekkfstks
dvwsfgillweiysfgrvpypriplkdvvprvekgykmdapdgcppavyevmkncwhlda
amrpsflqlreqlehikthelhl

    Sequence, based on observed residues (ATOM records): (download) 
    >3d7uA (A:)
walnmkelkllqtigkgefgdvmlgdyrgnkvavkcikndataqaflaeasvmtqlrhsn
lvqllgviveekgglyivteymakgslvdylrsrgrsvlggdcllkfsldvceameyleg
nnfvhrdlaarnvlvsednvakvsdfgltkeasklpvkwtapealrekkfstksdvwsfg
illweiysfgrvpypriplkdvvprvekgykmdapdgcppavyevmkncwhldaamrpsf
lqlreqlehikthelhl

  • Chain 'B':
    No sequence available.

  • Chain 'C':
    Sequence, based on SEQRES records: (download) 
    >3d7uC (C:)
walnmkelkllqtigkgefgdvmlgdyrgnkvavkcikndataqaflaeasvmtqlrhsn
lvqllgviveekgglyivteymakgslvdylrsrgrsvlggdcllkfsldvceameyleg
nnfvhrdlaarnvlvsednvakvsdfgltkeasstqdtgklpvkwtapealrekkfstks
dvwsfgillweiysfgrvpypriplkdvvprvekgykmdapdgcppavyevmkncwhlda
amrpsflqlreqlehikthelhl

    Sequence, based on observed residues (ATOM records): (download) 
    >3d7uC (C:)
walnmkelkllqtigkgefgdvmlgdyrgnkvavkcikndataqaflaeasvmtqlrhsn
lvqllgviveekgglyivteymakgslvdylrsrgrsvlggdcllkfsldvceameyleg
nnfvhrdlaarnvlvsednvakvsdfgltkeasklpvkwtapealrekkfstksdvwsfg
illweiysfgrvpypriplkdvvprvekgykmdapdgcppavyevmkncwhldaamrpsf
lqlreqlehikthelhl

  • Chain 'D':
    No sequence available.