PDB entry 3d4s

View 3d4s on RCSB PDB site
Description: cholesterol bound form of human beta2 adrenergic receptor.
Deposited on 2008-05-14, released 2008-06-17
The last revision was dated 2021-10-20, with a file datestamp of 2021-10-15.
Experiment type: XRAY
Resolution: 2.8 Å
R-factor: N/A
AEROSPACI score: 0.18 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: Beta-2 adrenergic receptor/T4-lysozyme chimera
    Species: Homo sapiens [TaxId:9606]
    Gene: ADRB2, ADRB2R, B2AR / E
    Database cross-references and differences (RAF-indexed):
    • Uniprot P07550 (8-237)
      • expression tag (0-7)
      • engineered mutation (129)
      • engineered mutation (194)
      • engineered mutation (290)
      • engineered mutation (333)
      • expression tag (484-489)
    • Uniprot P00720 (238-397)
    • Uniprot P07550 (398-483)
  • Heterogens: TIM, CLR, OLC, HOH

PDB Chain Sequences:
This PDB entry is not classified in SCOPe 2.08, so the chain sequences below are not included in the ASTRAL sequence sets.

  • Chain 'A':
    Sequence, based on SEQRES records:
    >3d4sA (A:)
dykddddamgqpgngsafllapnrshapdhdvtqqrdevwvvgmgivmslivlaivfgnv
lvitaiakferlqtvtnyfitslacadlvmglavvpfgaahilmkmwtfgnfwcefwtsi
dvlcvtasiwtlcviavdryfaitspfkyqslltknkarviilmvwivsgltsflpiqmh
wyrathqeaincyaeetccdfftnqayaiassivsfyvplvimvfvysrvfqeakrqlni
femlrideglrlkiykdtegyytigighlltkspslnaakseldkaigrntngvitkdea
eklfnqdvdaavrgilrnaklkpvydsldavrraalinmvfqmgetgvagftnslrmlqq
krwdeaavnlaksrwynqtpnrakrvittfrtgtwdaykfclkehkalktlgiimgtftl
cwlpffivnivhviqdnlirkevyillnwigyvnsgfnpliycrspdfriafqellclrr
sslkhhhhhh

    Sequence, based on observed residues (ATOM records):
    >3d4sA (A:)
wvvgmgivmslivlaivfgnvlvitaiakferlqtvtnyfitslacadlvmglavvpfga
ahilmkmwtfgnfwcefwtsidvlcvtasiwtlcviavdryfaitspfkyqslltknkar
viilmvwivsgltsflpiqmhwyrathqeaincyaeetccdfftnqayaiassivsfyvp
lvimvfvysrvfqeakrqlnifemlrideglrlkiykdtegyytigighlltkspslnaa
kseldkaigrntngvitkdeaeklfnqdvdaavrgilrnaklkpvydsldavrraalinm
vfqmgetgvagftnslrmlqqkrwdeaavnlaksrwynqtpnrakrvittfrtgtwdayk
fclkehkalktlgiimgtftlcwlpffivnivhviqdnlirkevyillnwigyvnsgfnp
liycrspdfriafqellcl