PDB entry 3d3l

View 3d3l on RCSB PDB site
Description: the 2.6 a crystal structure of the lipoxygenase domain of human arachidonate 12-lipoxygenase, 12s-type
Deposited on 2008-05-12, released 2008-09-09
The last revision was dated 2021-10-20, with a file datestamp of 2021-10-15.
Experiment type: XRAY
Resolution: 2.6 Å
R-factor: 0.21
AEROSPACI score: 0.29 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: Arachidonate 12-lipoxygenase, 12S-type
    Species: Homo sapiens [TaxId:9606]
    Gene: ALOX12, LOG12
    Database cross-references and differences (RAF-indexed):
    • Uniprot P18054 (17-508)
      • expression tag (0-16)
      • variant (106)
      • engineered mutation (508)
      • expression tag (509-540)
  • Chain 'B':
    Compound: Arachidonate 12-lipoxygenase, 12S-type
    Species: Homo sapiens [TaxId:9606]
    Gene: ALOX12, LOG12
    Database cross-references and differences (RAF-indexed):
    • Uniprot P18054 (17-508)
      • expression tag (0-16)
      • variant (106)
      • engineered mutation (508)
      • expression tag (509-540)
  • Heterogens: FE, HOH

PDB Chain Sequences:
This PDB entry is not classified in SCOPe 2.08, so the chain sequences below are not included in the ASTRAL sequence sets.

  • Chain 'A':
    Sequence, based on SEQRES records:
    >3d3lA (A:)
mhhhhhhssgvdlgtenldfewtlkagalemalkrvytllsswncledfdqifwgqksal
aekvrqcwqddelfsyqflnganpmllrrstslpsrlvlpsgmeelraqlekelqngslf
eadfilldgipanvirgekqylaaplvmlkmepngklqpmviqiqppnpssptptlflps
dpplawllakswvrnsdfqlheiqyhllnthlvaeviavatmrclpglhpifkfliphir
ytmeintrartqlisdggifdkavstgggghvqllrraaaqltycslcppddladrgllg
lpgalyahdalrlweiiaryvegivhlfyqrddivkgdpelqawcreitevglcqaqdrg
fpvsfqsqsqlchfltmcvftctaqhaainqgqldwyawvpnapctmrmpppttkedvtm
atvmgslpdvrqaclqmaiswhlsrrqpdmvplghhkekyfsgpkpkavlnqfrtdlekl
ekeitarneqldwpyeylkpsciensvtsdskggygsefelrrqacgrtrappppplrsg
c

    Sequence, based on observed residues (ATOM records):
    >3d3lA (A:)
wtlkagalemalkrvytllsswncledfdqifwgqksalaekvrqcwqddelfsyqflng
anpmllrrstslpsrlvlpsgmeelraqlekelqngslfeadfilldgipaekqylaapl
vmlkmepngklqpmviqiqppnpssptptlflpsdpplawllakswvrnsdfqlheiqyh
llnthlvaeviavatmrclpglhpifkfliphirygghvqllrraaaqltycslcppddl
adrgllglpgalyahdalrlweiiaryvegivhlfyqrddivkgdpelqawcreitevgl
cqaqdrgfpvsfqsqsqlchfltmcvftctaqhaainqgqldwyawvpnapctmrmpppt
tkedvtmatvmgslpdvrqaclqmaiswhlsdmvplghhkekyfsgpkpkavlnqfrtdl
eklekeitarneqldwpyeylkpsciensvt

  • Chain 'B':
    Sequence, based on SEQRES records:
    >3d3lB (B:)
mhhhhhhssgvdlgtenldfewtlkagalemalkrvytllsswncledfdqifwgqksal
aekvrqcwqddelfsyqflnganpmllrrstslpsrlvlpsgmeelraqlekelqngslf
eadfilldgipanvirgekqylaaplvmlkmepngklqpmviqiqppnpssptptlflps
dpplawllakswvrnsdfqlheiqyhllnthlvaeviavatmrclpglhpifkfliphir
ytmeintrartqlisdggifdkavstgggghvqllrraaaqltycslcppddladrgllg
lpgalyahdalrlweiiaryvegivhlfyqrddivkgdpelqawcreitevglcqaqdrg
fpvsfqsqsqlchfltmcvftctaqhaainqgqldwyawvpnapctmrmpppttkedvtm
atvmgslpdvrqaclqmaiswhlsrrqpdmvplghhkekyfsgpkpkavlnqfrtdlekl
ekeitarneqldwpyeylkpsciensvtsdskggygsefelrrqacgrtrappppplrsg
c

    Sequence, based on observed residues (ATOM records):
    >3d3lB (B:)
wtlkagalemalkrvytllsswncledfdqifwgqksalaekvrqcwqddelfsyqflng
anpmllrrstslpsrlvlpsgmeelraqlekelqngslfeadfilldgipaqylaaplvm
lkmepngklqpmviqiqppnpssptptlflpsdpplawllakswvrnsdfqlheiqyhll
nthlvaeviavatmrclpglhpifkfliphigghvqllrraaaqltycslcppddladrg
llglpgalyahdalrlweiiaryvegivhlfyqrddivkgdpelqawcreitevglcqaq
drgfpvsfqsqsqlchfltmcvftctaqhaainqgqldwyawvpnapctmrmpppttked
vtmatvmgslpdvrqaclqmaiswhlsrmvplghhkekyfsgpkpkavlnqfrtdlekle
keitarneqldwpyeylkpsciensvt