PDB entry 3d2u
View 3d2u on RCSB PDB site
Description: Structure of UL18, a Peptide-Binding Viral MHC Mimic, Bound to a Host Inhibitory Receptor
Class: immune system
Keywords: MHC class I homolog, Disease mutation, Glycation, Glycoprotein, Immune response, Immunoglobulin domain, MHC I, Pyrrolidone carboxylic acid, Secreted, Membrane, Phosphoprotein, Receptor, Transmembrane, IMMUNE SYSTEM
Deposited on
2008-05-08, released
2008-07-08
The last revision prior to the SCOPe 2.06 freeze date was dated
2011-07-13, with a file datestamp of
2011-05-25.
Experiment type: XRAY
Resolution: 2.21 Å
R-factor: 0.241
AEROSPACI score: 0.33
(click here for full SPACI score report)
Chains and heterogens:
- Chain 'A':
Compound: UL18 protein
Species: Human herpesvirus 5 [TaxId:10359]
Database cross-references and differences (RAF-indexed):
- Uniprot Q4A1U8 (0-280)
- engineered (35)
- engineered (146)
- variant (185)
- engineered (219)
- engineered (258)
- Chain 'B':
Compound: Beta-2-microglobulin
Species: Homo sapiens [TaxId:9606]
Database cross-references and differences (RAF-indexed):
Domains in SCOPe 2.06: d3d2ub_ - Chain 'C':
Compound: actin
Species: HOMO SAPIENS, synthetic [TaxId:9606]
Database cross-references and differences (RAF-indexed):
- Chain 'D':
Compound: Leukocyte immunoglobulin-like receptor subfamily B member 1
Species: Homo sapiens [TaxId:9606]
Database cross-references and differences (RAF-indexed):
- Uniprot Q8NHL6 (Start-197)
- variant (44)
- variant (118)
- variant (131)
Domains in SCOPe 2.06: d3d2ud1, d3d2ud2 - Chain 'E':
Compound: UL18 protein
Species: Human herpesvirus 5 [TaxId:10359]
Database cross-references and differences (RAF-indexed):
- Uniprot Q4A1U8
- engineered (35)
- engineered (146)
- variant (185)
- engineered (219)
- engineered (258)
- Chain 'F':
Compound: Beta-2-microglobulin
Species: Homo sapiens [TaxId:9606]
Database cross-references and differences (RAF-indexed):
Domains in SCOPe 2.06: d3d2uf_ - Chain 'G':
Compound: actin
Species: HOMO SAPIENS, synthetic [TaxId:9606]
Database cross-references and differences (RAF-indexed):
- Chain 'H':
Compound: Leukocyte immunoglobulin-like receptor subfamily B member 1
Species: Homo sapiens [TaxId:9606]
Database cross-references and differences (RAF-indexed):
- Uniprot Q8NHL6 (Start-197)
- variant (44)
- variant (118)
- variant (131)
Domains in SCOPe 2.06: d3d2uh1, d3d2uh2 - Heterogens: NAG, MAN, BMA, FUC, HOH
PDB Chain Sequences:
- Chain 'A':
No sequence available.
- Chain 'B':
Sequence; same for both SEQRES and ATOM records: (download)
>3d2uB (B:)
iqrtpkiqvysrhpaengksnflncyvsgfhpsdievdllkngeriekvehsdlsfskdw
sfyllyyteftptekdeyacrvnhvtlsqpkivkwdrdm
- Chain 'C':
No sequence available.
- Chain 'D':
Sequence, based on SEQRES records: (download)
>3d2uD (D:)
ghlpkptlwaepgsvitqgspvtlrcqggqetqeyrlyrekktapwitripqelvkkgqf
pipsitwehagryrcyygsdtagrsessdplelvvtgayikptlsaqpspvvnsggnvtl
qcdsqvafdgfilckegedehpqclnsqphargssraifsvgpvspsrrwwyrcyaydsn
spyewslpsdllellvlg
Sequence, based on observed residues (ATOM records): (download)
>3d2uD (D:)
pkptlwaepgsvitqgspvtlrcqggqetqeyrlyrekktapwitripqelvkkgqfpip
sitwehagryrcyygsdtagrsessdplelvvtgayikptlsaqpspvvnsggnvtlqcd
sqvafdgfilckeqclnssraifsvgpvspsrrwwyrcyaydsnspyewslpsdllellv
lg
- Chain 'E':
No sequence available.
- Chain 'F':
Sequence; same for both SEQRES and ATOM records: (download)
>3d2uF (F:)
iqrtpkiqvysrhpaengksnflncyvsgfhpsdievdllkngeriekvehsdlsfskdw
sfyllyyteftptekdeyacrvnhvtlsqpkivkwdrdm
- Chain 'G':
No sequence available.
- Chain 'H':
Sequence, based on SEQRES records: (download)
>3d2uH (H:)
ghlpkptlwaepgsvitqgspvtlrcqggqetqeyrlyrekktapwitripqelvkkgqf
pipsitwehagryrcyygsdtagrsessdplelvvtgayikptlsaqpspvvnsggnvtl
qcdsqvafdgfilckegedehpqclnsqphargssraifsvgpvspsrrwwyrcyaydsn
spyewslpsdllellvlg
Sequence, based on observed residues (ATOM records): (download)
>3d2uH (H:)
hlpkptlwaepgsvitqgspvtlrcqggqetqeyrlyrekktapwitripqelvkkgqfp
ipsitwehagryrcyygsdtagrsessdplelvvtgayikptlsaqpspvvnsggnvtlq
cdsqvafdgfilckegeqclnsraifsvgpvspsrrwwyrcyaydsnspyewslpsdlle
llvlg