PDB entry 3d2r

View 3d2r on RCSB PDB site
Description: Crystal structure of pyruvate dehydrogenase kinase isoform 4 in complex with ADP
Class: transferase
Keywords: protein-nucleotide complex, homodimer, ghkl superfamily, kinase, Carbohydrate metabolism, Glucose metabolism, Mitochondrion, Phosphoprotein, Transferase, Transit peptide
Deposited on 2008-05-08, released 2008-08-05
The last revision prior to the SCOPe 2.08 freeze date was dated 2011-07-13, with a file datestamp of 2011-05-08.
Experiment type: XRAY
Resolution: 2.03 Å
R-factor: 0.185
AEROSPACI score: 0.44 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: [Pyruvate dehydrogenase [lipoamide]] kinase isozyme 4
    Species: Homo sapiens [TaxId:9606]
    Gene: PDK4
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.08: d3d2ra1, d3d2ra2
  • Chain 'B':
    Compound: [Pyruvate dehydrogenase [lipoamide]] kinase isozyme 4
    Species: Homo sapiens [TaxId:9606]
    Gene: PDK4
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.08: d3d2rb1, d3d2rb2
  • Heterogens: MG, ADP, GOL, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download) 
    >3d2rA (A:)
asvprevehfsryspsplsmkqlldfgsenacertsfaflrqelpvrlanilkeidilpt
qlvntssvqlvkswyiqslmdlvefhekspddqkalsdfvdtlikvrnrhhnvvptmaqg
iieykdactvdpvtnqnlqyfldrfymnristrmlmnqhilifsdsqtgnpshigsidpn
cdvvavvqdafecsrmlcdqyylsspelkltqvngkfpdqpihivyvpshlhhmlfelfk
namratvehqenqpsltpievivvlgkedltikisdrgggvplriidrlfsytystaptp
vmdnsrnaplagfgyglpisrlyakyfqgdlnlyslsgygtdaiiylkalssesieklpv
fnksafkhyqmsseaddwcipsrepknlakevam

    Sequence, based on observed residues (ATOM records): (download) 
    >3d2rA (A:)
prevehfsryspsplsmkqlldfgsencertsfaflrqelpvrlanilkeidilptqlvn
tssvqlvkswyiqslmdlvefhekspddqkalsdfvdtlikvrnrhhnvvptmaqgiiey
kdacdpvtnqnlqyfldrfymnristrmlmnqhilifsdshigsidpncdvvavvqdafe
csrmlcdqyylsspelkltqvngkfpdqpihivyvpshlhhmlfelfknamratvehqen
qpsltpievivvlgkedltikisdrgggvplriidrlfsytystaptaplagfgyglpis
rlyakyfqgdlnlyslsgygtdaiiylkalssesieklpvfnksafkhyddwci

  • Chain 'B':
    Sequence, based on SEQRES records: (download) 
    >3d2rB (B:)
asvprevehfsryspsplsmkqlldfgsenacertsfaflrqelpvrlanilkeidilpt
qlvntssvqlvkswyiqslmdlvefhekspddqkalsdfvdtlikvrnrhhnvvptmaqg
iieykdactvdpvtnqnlqyfldrfymnristrmlmnqhilifsdsqtgnpshigsidpn
cdvvavvqdafecsrmlcdqyylsspelkltqvngkfpdqpihivyvpshlhhmlfelfk
namratvehqenqpsltpievivvlgkedltikisdrgggvplriidrlfsytystaptp
vmdnsrnaplagfgyglpisrlyakyfqgdlnlyslsgygtdaiiylkalssesieklpv
fnksafkhyqmsseaddwcipsrepknlakevam

    Sequence, based on observed residues (ATOM records): (download) 
    >3d2rB (B:)
vprevehfsryspsplsmkqlldfgsenacertsfaflrqelpvrlanilkeidilptql
vntssvqlvkswyiqslmdlvefhekspddqkalsdfvdtlikvrnrhhnvvptmaqgii
eykactvdpvtnqnlqyfldrfymnristrmlmnqhilifsdsqtgnpshigsidpncdv
vavvqdafecsrmlcdqyylsspelkltqvngkfpdqpihivyvpshlhhmlfelfknam
ratvehqenqpsltpievivvlgkedltikisdrgggvplriidrlfsytystaptppla
gfgyglpisrlyakyfqgdlnlyslsgygtdaiiylkalssesieklpvfnksafkhydw
ci