PDB entry 3cy2

View 3cy2 on RCSB PDB site
Description: crystal structure of human proto-oncogene serine threonine kinase (pim1) in complex with a consensus peptide and a beta carboline ligand ii
Deposited on 2008-04-25, released 2008-07-15
The last revision was dated 2021-10-20, with a file datestamp of 2021-10-15.
Experiment type: XRAY
Resolution: 2.01 Å
R-factor: N/A
AEROSPACI score: 0.31 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: Proto-oncogene serine/threonine-protein kinase Pim-1, Isoform 2
    Species: Homo sapiens [TaxId:9606]
    Gene: PIM1
    Database cross-references and differences (RAF-indexed):
    • Uniprot P11309 (1-313)
      • expression tag (0)
      • engineered mutation (250)
  • Chain 'B':
    Compound: Pimtide peptide
    Species: synthetic, synthetic
    Database cross-references and differences (RAF-indexed):
    • PDB 3CY2 (0-13)
  • Heterogens: CL, MB9, EDO, HOH

PDB Chain Sequences:
This PDB entry is not classified in SCOPe 2.08, so the chain sequences below are not included in the ASTRAL sequence sets.

  • Chain 'A':
    Sequence, based on SEQRES records:
    >3cy2A (A:)
smllskinslahlraapcndlhatklapgkekeplesqyqvgpllgsggfgsvysgirvs
dnlpvaikhvekdrisdwgelpngtrvpmevvllkkvssgfsgvirlldwferpdsfvli
lerpepvqdlfdfitergalqeelarsffwqvleavrhchncgvlhrdikdenilidlnr
gelklidfgsgallkdtvytdfdgtrvysppewiryhryhgrsaavwslgillydmvcgd
ipfehdeeiiggqvffrqrvssecqhlirwclalrpsdrptfeeiqnhpwmqdvllpqet
aeihlhslspgpsk

    Sequence, based on observed residues (ATOM records):
    >3cy2A (A:)
plesqyqvgpllgsggfgsvysgirvsdnlpvaikhvekdrisdwgelptrvpmevvllk
kvssgfsgvirlldwferpdsfvlilerpepvqdlfdfitergalqeelarsffwqvlea
vrhchncgvlhrdikdenilidlnrgelklidfgsgallkdtvytdfdgtrvysppewir
yhryhgrsaavwslgillydmvcgdipfehdeeiiggqvffrqrvssecqhlirwclalr
psdrptfeeiqnhpwmqdvllpqetaeihlh

  • Chain 'B':
    Sequence, based on SEQRES records:
    >3cy2B (B:)
arkrrrhpsgppta

    Sequence, based on observed residues (ATOM records):
    >3cy2B (B:)
rkrrrhpsg