PDB entry 3cxe

View 3cxe on RCSB PDB site
Description: structure of the gm-csf receptor complex
Deposited on 2008-04-24, released 2008-08-26
Made obsolete by 4nkq on 2015-09-23

The last revision was dated 2015-09-23, with a file datestamp of 2015-09-18.
Experiment type: XRAY
Resolution: 3.3 Å
R-factor: N/A
AEROSPACI score: 0.08 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: Cytokine receptor common subunit beta
    Species: Homo sapiens [TaxId:9606]
    Gene: CSF2RB, IL3RB, IL5RB
    Database cross-references and differences (RAF-indexed):
    • Uniprot P32927 (0-End)
      • engineered (321)
  • Chain 'B':
    Compound: granulocyte-macrophage colony-stimulating factor
    Species: Homo sapiens [TaxId:9606]
    Gene: CSF2, GMCSF
    Database cross-references and differences (RAF-indexed):
  • Chain 'C':
    Compound: Granulocyte-macrophage colony-stimulating factor receptor subunit alpha
    Species: Homo sapiens [TaxId:9606]
    Gene: CSF2RA, CSF2R, CSF2RY
    Database cross-references and differences (RAF-indexed):
  • Heterogens: NAG

PDB Chain Sequences:
This PDB entry is not classified in SCOPe 2.08, so the chain sequences below are not included in the ASTRAL sequence sets.

  • Chain 'A':
    Sequence, based on SEQRES records:
    >3cxeA (A:)
eetiplqtlrcyndytshitcrwadtqdaqrlvnvtlirrvnedllepvscdlsddmpws
acphprcvprrcvipcqsfvvtdvdyfsfqpdrplgtrltvtltqhvqppeprdlqistd
qdhflltwsvalgspqshwlspgdlefevvykrlqdswedaaillsntsqatlgpehlmp
sstyvarvrtrlapgsrlsgrpskwspevcwdsqpgdeaqpqnlecffdgaavlscswev
rkevassvsfglfykpspdageeecspvlreglgslhtrhhcqipvpdpathgqyivsvq
prraekhikssvniqmappslqvtkdgdsyslrwetmkmryehidhtfeiqyrkdtatwk
dsktetlqnahsmalpalepstrywarvrvrtsrtgyngiwsewsearswdtes

    Sequence, based on observed residues (ATOM records):
    >3cxeA (A:)
eetiplqtlrcyndytshitcrwadtqdaqrlvnvtlirrvnedllepvscdlsddmpws
acphprcvprrcvipcqsfvvtdvdyfsfqpdrplgtrltvtltqhvqppeprdlqistd
qdhflltwsvalgspqshwlspgdlefevvykrlqdswedaaillsntsqatlgpehlmp
sstyvarvrtrlapgsrlsgrpskwspevcwdsqpgdeaqpqnlecffdgaavlscswev
rkevassvsfglfykpspdageeecspvlreglgslhtrhhcqipvpdpathgqyivsvq
prraekhikssvniqmappslqvtkdgdsyslrwetmkmryehidhtfeiqyrkdtatwk
dsktetlqnahsmalpalepstrywarvrvrtsrtgyngiwsewsearswdt

  • Chain 'B':
    Sequence, based on SEQRES records:
    >3cxeB (B:)
aparspspstqpwehvnaiqearrllnlsrdtaaemnetvevisemfdlqeptclqtrle
lykqglrgsltklkgpltmmashykqhcpptpetscatqiitfesfkenlkdfllvipfd
cwepvqe

    Sequence, based on observed residues (ATOM records):
    >3cxeB (B:)
ehvnaiqearrllnlsrdtaaemnetvevisemfdlqeptclqtrlelykqglrgsltkl
kgpltmmashykqhcpptpetscatqiitfesfkenlkdfllvip

  • Chain 'C':
    Sequence, based on SEQRES records:
    >3cxeC (C:)
xxxxxxxxxxxxxxxxxfnppsnvtvrcntthclvrwkqprtyqklsyldfqyqldvhrk
ntqpgtenllinvsgdlenrynfpsseprakhsvkiraadvrilnwsswseaiefgsddg

    Sequence, based on observed residues (ATOM records):
    >3cxeC (C:)
xxxxxxxxxxxxxxxxxfnppsnvtvrcntthclvrwkqprtyqklsyldfqyqldvhrk
ntqpgtenllinvsgdlenrynfpsseprakhsvkiraadvrilnwsswseaiefg