PDB entry 3cv8

View 3cv8 on RCSB PDB site
Description: Crystal structure of vitamin D hydroxylase cytochrome P450 105A1 (R84F mutant)
Class: oxidoreductase
Keywords: p450, beta prism, heme, iron, metal-binding, monooxygenase, oxidoreductase
Deposited on 2008-04-18, released 2008-11-04
The last revision prior to the SCOPe 2.03 freeze date was dated 2009-02-24, with a file datestamp of 2009-02-03.
Experiment type: XRAY
Resolution: 2 Å
R-factor: 0.184
AEROSPACI score: 0.46 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: Cytochrome P450-SU1
    Species: Streptomyces griseolus [TaxId:1909]
    Gene: CYP105A1
    Database cross-references and differences (RAF-indexed):
    • Uniprot P18326 (Start-405)
      • engineered (83)
      • see remark 999 (307)
      • expression tag (406-407)
    Domains in SCOPe 2.03: d3cv8a_
  • Heterogens: HEM, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download) 
    >3cv8A (A:)
mtdtattpqttdapafpsnrscpyqlpdgyaqlrdtpgplhrvtlydgrqawvvtkheaa
rkllgdprlssnrtddnfpatspffeavrespqafigldppehgtrrrmtiseftvkrik
gmrpeveevvhgfldemlaagptadlvsqfalpvpsmvicrllgvpyadheffqdaskrl
vqstdaqsaltarndlagyldglitqfqtepgaglvgalvadqlangeidreelistaml
lliaghettasmtslsvitlldhpeqyaalradrslvpgaveellrylaiadiaggrvat
adievegqliragegvivvnsianrdgtvyedpdaldihrsarhhlafgfgvhqclgqnl
arlelevilnalmdrvptlrlavpveqlvlrpgttiqgvnelpvtwhhhhhh

    Sequence, based on observed residues (ATOM records): (download) 
    >3cv8A (A:)
tpqttdapafpsnrscpyqlpdgyaqlrdtpgplhrvtlydgrqawvvtkheaarkllgd
prlssnrtddnfpatspffeavrespqafigldppehgtrrrmtiseftvkrikgmrpev
eevvhgfldemlaagptadlvsqfalpvpsmvicrllgvpyadheffqdaskrlvqstda
qsaltarndlagyldglitqfqtepgaglvgalvadqlangeidreelistamllliagh
ettasmtslsvitlldhpeqyaalradrslvpgaveellrylaiadiaggrvatadieve
gqliragegvivvnsianrdgtvyedpdaldihrsarhhlafgfgvhqclgqnlarlele
vilnalmdrvptlrlavpveqlvlrpgttiqgvnelpvtwhh