PDB entry 3csy

View 3csy on RCSB PDB site
Description: Crystal structure of the trimeric prefusion Ebola virus glycoprotein in complex with a neutralizing antibody from a human survivor
Class: immune system/viral protein
Keywords: glycoprotein-antibody complex, IMMUNE SYSTEM-VIRAL PROTEIN COMPLEX
Deposited on 2008-04-10, released 2008-07-08
The last revision prior to the SCOPe 2.08 freeze date was dated 2021-03-31, with a file datestamp of 2021-03-26.
Experiment type: XRAY
Resolution: 3.4 Å
R-factor: N/A
AEROSPACI score: 0.15 (click here for full SPACI score report)

Chains and heterogens:

• Chain 'A':
  Compound: Fab KZ52 heavy chain
  Species: Homo sapiens [TaxId:9606]
  Database cross-references and differences (RAF-indexed):
  • PDB 3CSY (0-225)
• Chain 'B':
  Compound: Fab KZ52 light chain
  Species: Homo sapiens [TaxId:9606]
  Database cross-references and differences (RAF-indexed):
  • PDB 3CSY (0-216)
• Chain 'C':
  Compound: Fab KZ52 heavy chain
  Species: Homo sapiens [TaxId:9606]
  Database cross-references and differences (RAF-indexed):
  • PDB 3CSY (0-225)
• Chain 'D':
  Compound: Fab KZ52 light chain
  Species: Homo sapiens [TaxId:9606]
  Database cross-references and differences (RAF-indexed):
  • PDB 3CSY (0-216)
• Chain 'E':
  Compound: Fab KZ52 heavy chain
  Species: Homo sapiens [TaxId:9606]
  Database cross-references and differences (RAF-indexed):
  • PDB 3CSY (0-225)
• Chain 'F':
  Compound: Fab KZ52 light chain
  Species: Homo sapiens [TaxId:9606]
  Database cross-references and differences (RAF-indexed):
  • PDB 3CSY (0-216)
• Chain 'G':
  Compound: Fab KZ52 heavy chain
  Species: Homo sapiens [TaxId:9606]
  Database cross-references and differences (RAF-indexed):
  • PDB 3CSY (0-225)
• Chain 'H':
  Compound: Fab KZ52 light chain
  Species: Homo sapiens [TaxId:9606]
  Database cross-references and differences (RAF-indexed):
  • PDB 3CSY (0-216)
• Chain 'I':
  Compound: Envelope glycoprotein GP1
  Species: Ebola virus - Mayinga, Zaire, 1976 [TaxId:128952]
  Gene: GP
  Database cross-references and differences (RAF-indexed):
  • Uniprot Q05320 (16-End)
    • expression tag (15)
    • engineered (26)
    • engineered (214)
  Domains in SCOPe 2.08: d3csyi1, d3csyi2
• Chain 'J':
  Compound: Envelope glycoprotein GP2
  Species: Ebola virus - Mayinga, Zaire, 1976 [TaxId:128952]
  Gene: GP
  Database cross-references and differences (RAF-indexed):
  • Uniprot P87666 (0-End)
• Chain 'K':
  Compound: Envelope glycoprotein GP1
  Species: Ebola virus - Mayinga, Zaire, 1976 [TaxId:128952]
  Gene: GP
  Database cross-references and differences (RAF-indexed):
  • Uniprot Q05320 (16-End)
    • expression tag (15)
    • engineered (26)
    • engineered (214)
• Chain 'L':
  Compound: Envelope glycoprotein GP2
  Species: Ebola virus - Mayinga, Zaire, 1976 [TaxId:128952]
  Gene: GP
  Database cross-references and differences (RAF-indexed):
  • Uniprot P87666
• Chain 'M':
  Compound: Envelope glycoprotein GP1
  Species: Ebola virus - Mayinga, Zaire, 1976 [TaxId:128952]
  Gene: GP
  Database cross-references and differences (RAF-indexed):
  • Uniprot Q05320 (16-End)
    • expression tag (15)
    • engineered (26)
    • engineered (214)
• Chain 'N':
  Compound: Envelope glycoprotein GP2
  Species: Ebola virus - Mayinga, Zaire, 1976 [TaxId:128952]
  Gene: GP
  Database cross-references and differences (RAF-indexed):
  • Uniprot P87666 (0-End)
• Chain 'O':
  Compound: Envelope glycoprotein GP1
  Species: Ebola virus - Mayinga, Zaire, 1976 [TaxId:128952]
  Gene: GP
  Database cross-references and differences (RAF-indexed):
  • Uniprot Q05320 (16-End)
    • expression tag (15)
    • engineered (26)
    • engineered (214)
• Chain 'P':
  Compound: Envelope glycoprotein GP2
  Species: Ebola virus - Mayinga, Zaire, 1976 [TaxId:128952]
  Gene: GP
  Database cross-references and differences (RAF-indexed):
  • Uniprot P87666

PDB Chain Sequences:

• Chain 'A':
  No sequence available.
  
  
• Chain 'B':
  No sequence available.
  
  
• Chain 'C':
  No sequence available.
  
  
• Chain 'D':
  No sequence available.
  
  
• Chain 'E':
  No sequence available.
  
  
• Chain 'F':
  No sequence available.
  
  
• Chain 'G':
  No sequence available.
  
  
• Chain 'H':
  No sequence available.
  
  
• Chain 'I':
  Sequence, based on SEQRES records: (download)
  

  >3csyI (I:)
  ypydvpdyaiegrgarsiplgvihnsvlqvsdvdklvcrdklsstnqlrsvglnlegngv
  atdvpsatkrwgfrsgvppkvvnyeagewaencynleikkpdgseclpaapdgirgfprc
  ryvhkvsgtgpcagdfafhkegafflydrlastviyrgttfaegvvaflilpqakkdffs
  shplrepvnatedpssgyysttiryqatgfgtneveylfevdnltyvqlesrftpqfllq
  lnetiytsgkrsnttgkliwkvnpeidttigewafwetkknltrkirseelsftvvthhq
  dtgeesassgklglitntiagvaglitggrrtrr
  

  
  Sequence, based on observed residues (ATOM records): (download)
  

  >3csyI (I:)
  rsiplgvihnsvlqvsdvdklvcrdklsstnqlrsvglnlegngvatdvpsatkrwgfrs
  gvppkvvnyeagewaencynleikkpdgseclpaapdgirgfprcryvhkvsgtgpcagd
  fafhkegafflydrlastviyrgttfaegvvaflilpqaysttiryqatgfgtneveylf
  evdnltyvqlesrftpqfllqlnetiytsgkrsnttgkliwkvnrkirseelsftv
  

  
  
• Chain 'J':
  No sequence available.
  
  
• Chain 'K':
  No sequence available.
  
  
• Chain 'L':
  No sequence available.
  
  
• Chain 'M':
  No sequence available.
  
  
• Chain 'N':
  No sequence available.
  
  
• Chain 'O':
  No sequence available.
  
  
• Chain 'P':
  No sequence available.