PDB entry 3cst

View 3cst on RCSB PDB site
Description: crystal structure of pi3k p110gamma catalytical domain in complex with organoruthenium inhibitor e5e2
Deposited on 2008-04-10, released 2008-05-20
The last revision was dated 2017-10-25, with a file datestamp of 2017-10-20.
Experiment type: XRAY
Resolution: 3.2 Å
R-factor: N/A
AEROSPACI score: 0.11 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit gamma isoform
    Species: HOMO SAPIENS
    Gene: PIK3CG
    Database cross-references and differences (RAF-indexed):
    • Uniprot P48736 (1-End)
      • expression tag (0)
  • Heterogens: E52

PDB Chain Sequences:
This PDB entry is not classified in SCOPe 2.08, so the chain sequences below are not included in the ASTRAL sequence sets.

  • Chain 'A':
    Sequence, based on SEQRES records:
    >3cstA (A:)
mseesqafqrqltaligydvtdvsnvhddeleftrrglvtprmaevasrdpklyamhpwv
tskplpeylwkkianncifivihrsttsqtikvspddtpgailqsfftkmakkkslmdip
esqseqdfvlrvcgrdeylvgetpiknfqwvrhclkngeeihvvldtppdpaldevrkee
wplvddctgvtgyheqltihgkdhesvftvslwdcdrkfrvkirgidipvlprntdltvf
veaniqhgqqvlcqrrtspkpfteevlwnvwlefsikikdlpkgallnlqiycgkapals
skasaespsseskgkvqllyyvnlllidhrfllrrgeyvlhmwqisgkgedqgsfnadkl
tsatnpdkensmsisilldnychpialpkhqptpdpegdrvraempnqlrkqleaiiatd
plnpltaedkellwhfryeslkhpkaypklfssvkwgqqeivaktyqllarrevwdqsal
dvgltmqlldcnfsdenvraiavqklesledddvlhyllqlvqavkfepyhdsalarfll
krglrnkrighflfwflrseiaqsrhyqqrfavileaylrgcgtamlhdftqqvqvieml
qkvtldikslsaekydvssqvisqlkqklenlqnsqlpesfrvpydpglkagalaiekck
vmaskkkplwlefkcadptalsnetigiifkhgddlrqdmlilqilrimesiwetesldl
cllpygcistgdkigmieivkdattiakiqqstvgntgafkdevlnhwlkekspteekfq
aaverfvyscagycvatfvlgigdrhndnimitetgnlfhidfghilgnyksflginker
vpfvltpdflfvmgtsgkktsphfqkfqdicvkaylalrhhtnlliilfsmmlmtgmpql
tskedieyirdaltvgkneedakkyfldqievcrdkgwtvqfnwflhlvlgikqgekhsa
hhhhhh

    Sequence, based on observed residues (ATOM records):
    >3cstA (A:)
mseesqafqrqltaligydvtdvsnvhddeleftrrglvtprmaevasrdpklyamhpwv
tskplpeylwkkianncifivihrsttsqtikvspddtpgailqsfftkmaeqdfvlrvc
grdeylvgetpiknfqwvrhclkngeeihvvldtppdpaldevrkeecdrkfrvkirgid
ipvlprntdltvfveaniqhgqqvlcqrrtspkpfteevlwnvwlefsikikdlpkgall
nlqiycllyyvnlllidhrfllrrgeyvlhmwqisgfnadkltsatnpdkensmsisill
dnhpiaraempnqlrkqleaiiatdplnpltaedkellwhfryeslkhpkaypklfssvk
wgqqeivaktyqllarrevwdqsaldvgltmqlldcnfsdenvraiavqklesledddvl
hyllqlvqavkfepyhdsalarfllkrglrnkrighflfwflrseiaqsrhyqqrfavil
eaylrgcgtamlhdftqqvqviemlqkvtldikslsaekydvssqvisqlkqklenlqns
qlpesfrvpydpglkagalaiekckvmaskkkplwlefkcadptalsnetigiifkhgdd
lrqdmlilqilrimesiwetesldlcllpygcistgdkigmieivkdattiakiqqstvg
ntgfkdevlnhwlkekspteekfqaaverfvyscagycvatfvlgigdrhndnimitetg
nlfhidfghervpfvltpdflfvmgtsgkktsphfqkfqdicvkaylalrhhtnlliilf
smmlmtgmpqltskedieyirdaltvgkneedakkyfldqievcrdkgwtvqfnwf