PDB entry 3cs8
View 3cs8 on RCSB PDB site
Description: Structural and Biochemical Basis for the Binding Selectivity of PPARg to PGC-1a
Class: nuclear protein
Keywords: coactivator, nuclear receptor, Alternative splicing, Diabetes mellitus, Disease mutation, DNA-binding, Metal-binding, Nucleus, Obesity, Phosphoprotein, Polymorphism, Transcription, Transcription regulation, Zinc, Zinc-finger, RNA-binding, NUCLEAR PROTEIN
Deposited on
2008-04-09, released
2008-06-03
The last revision prior to the SCOPe 2.05 freeze date was dated
2009-02-24, with a file datestamp of
2009-03-01.
Experiment type: XRAY
Resolution: 2.3 Å
R-factor: 0.227
AEROSPACI score: 0.32
(click here for full SPACI score report)
Chains and heterogens:
- Chain 'A':
Compound: Peroxisome proliferator-activated receptor gamma
Species: HOMO SAPIENS
Gene: PPARGC1A, LEM6, PGC1, PGC1A, PPARGC1
Database cross-references and differences (RAF-indexed):
Domains in SCOPe 2.05: d3cs8a_ - Chain 'B':
Compound: PGC-1alfa peptide
Species: synthetic, synthetic
Database cross-references and differences (RAF-indexed):
- Heterogens: SO4, BRL, HOH
PDB Chain Sequences:
- Chain 'A':
Sequence, based on SEQRES records: (download)
>3cs8A (A:)
rggspesadlralakhlydsyiksfpltkakarailtgkttdkspfviydmnslmmgedk
ikfkhitplqeqskevairifqgcqfrsveavqeiteyaksipgfvnldlndqvtllkyg
vheiiytmlaslmnkdgvlisegqgfmtreflkslrkpfgdfmepkfefavkfnaleldd
sdlaifiaviilsgdrpgllnvkpiediqdnllqalelqlklnhpessqlfakllqkmtd
lrqivtehvqllqvikktetdmslhpllqeiykdl
Sequence, based on observed residues (ATOM records): (download)
>3cs8A (A:)
rggspesadlralakhlydsyiksfpltkakarailtgkttdkspfviydmnslmmgedk
iplqeqskevairifqgcqfrsveavqeiteyaksipgfvnldlndqvtllkygvheiiy
tmlaslmnkdgvlisegqgfmtreflkslrkpfgdfmepkfefavkfnalelddsdlaif
iaviilsgdrpgllnvkpiediqdnllqalelqlklnhpessqlfakllqkmtdlrqivt
ehvqllqvikktetdmslhpllqeiykdl
- Chain 'B':
No sequence available.