PDB entry 3cs4

View 3cs4 on RCSB PDB site
Description: Structure-based design of a superagonist ligand for the vitamin D nuclear receptor
Class: gene regulation
Keywords: VDR, superagonist, Disease mutation, DNA-binding, Metal-binding, Nucleus, Phosphoprotein, Polymorphism, Receptor, Transcription, Transcription regulation, Zinc, Zinc-finger, GENE REGULATION
Deposited on 2008-04-09, released 2008-05-27
The last revision prior to the SCOPe 2.01 freeze date was dated 2009-02-24, with a file datestamp of 2009-02-12.
Experiment type: XRAY
Resolution: 2 Å
R-factor: 0.186
AEROSPACI score: 0.48 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: Vitamin D3 receptor
    Species: Homo sapiens [TaxId:9606]
    Gene: Vdr, Nr1i1
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.01: d3cs4a_
  • Heterogens: COV, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download) 
    >3cs4A (A:)
gshmdslrpklseeqqriiailldahhktydptysdfcqfrppvrvndgggsvtlelsql
smlphladlvsysiqkvigfakmipgfrdltsedqivllkssaievimlrsnesftmddm
swtcgnqdykyrvsdvtkaghslelieplikfqvglkklnlheeehvllmaicivspdrp
gvqdaalieaiqdrlsntlqtyircrhpppgshllyakmiqkladlrslneehskqyrcl
sfqpecsmkltplvlevfgneis

    Sequence, based on observed residues (ATOM records): (download) 
    >3cs4A (A:)
slrpklseeqqriiailldahhktydptysdfcqfrppvrvndgggsvtlelsqlsmlph
ladlvsysiqkvigfakmipgfrdltsedqivllkssaievimlrsnesftmddmswtcg
nqdykyrvsdvtkaghslelieplikfqvglkklnlheeehvllmaicivspdrpgvqda
alieaiqdrlsntlqtyircrhpppgshllyakmiqkladlrslneehskqyrclsfqpe
csmkltplvlevfg