PDB entry 3crl

View 3crl on RCSB PDB site
Description: Crystal structure of the PDHK2-L2 complex.
Class: transferase
Keywords: pyruvate dehydrogenase kinase isozyme 2, transferase, glucose metabolism, kinase, mitochondrion, Carbohydrate metabolism, Transit peptide, Acyltransferase, Glycolysis, Lipoyl
Deposited on 2008-04-07, released 2008-04-29
The last revision prior to the SCOPe 2.08 freeze date was dated 2017-10-25, with a file datestamp of 2017-10-20.
Experiment type: XRAY
Resolution: 2.61 Å
R-factor: N/A
AEROSPACI score: 0.18 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: Pyruvate dehydrogenase [lipoamide] kinase isozyme 2, mitochondrial
    Species: Rattus norvegicus [TaxId:10116]
    Gene: Pdk2
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.08: d3crla1, d3crla2
  • Chain 'B':
    Compound: Pyruvate dehydrogenase [lipoamide] kinase isozyme 2, mitochondrial
    Species: Rattus norvegicus [TaxId:10116]
    Gene: Pdk2
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.08: d3crlb1, d3crlb2
  • Chain 'C':
    Compound: Dihydrolipoyllysine-residue acetyltransferase component of pyruvate dehydrogenase complex, mitochondrial
    Species: Homo sapiens [TaxId:9606]
    Gene: DLAT, DLTA
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.08: d3crlc_
  • Chain 'D':
    Compound: Dihydrolipoyllysine-residue acetyltransferase component of pyruvate dehydrogenase complex, mitochondrial
    Species: Homo sapiens [TaxId:9606]
    Gene: DLAT, DLTA
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.08: d3crld_
  • Heterogens: MG, K, ANP, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download) 
    >3crlA (A:)
mrwfrallknaslagapkyiehfskfspsplsmkqfldfgssnacektsftflrqelpvr
lanimkeinllpdrvlstpsvqlvqswyvqslldimefldkdpedhrtlsqftdalvtir
nrhndvvptmaqgvleykdtygddpvsnqniqyfldrfylsrisirmlinqhtlifdgst
npahpkhigsidpncsvsdvvkdaydmakllcdkyymaspdleiqevnatnatqpihmvy
vpshlyhmlfelfknamratveshessltlppikimvalgeedlsikmsdrgggvplrki
erlfsymystaptpqpgtggtplagfgyglpisrlyakyfqgdlqlfsmegfgtdaviyl
kalstdsverlpvynksawrhyqtiqeagdwcvpstepkntstyrvs

    Sequence, based on observed residues (ATOM records): (download) 
    >3crlA (A:)
slagapkyiehfskfspsplsmkqfldfgssnacektsftflrqelpvrlanimkeinll
pdrvlstpsvqlvqswyvqslldimefldkdpedhrtlsqftdalvtirnrhndvvptma
qgvleykdtygddpvsnqniqyfldrfylsrisirmlinqhtlifdgstnpahpkhigsi
dpncsvsdvvkdaydmakllcdkyymaspdleiqevnatnatqpihmvyvpshlyhmlfe
lfknamratveshessltlppikimvalgeedlsikmsdrgggvplrkierlfsymysta
plagfgyglpisrlyakyfqgdlqlfsmegfgtdaviylkalstdsverlpvynksawrh
yqtiqeagdwcvpstepknts

  • Chain 'B':
    Sequence, based on SEQRES records: (download) 
    >3crlB (B:)
mrwfrallknaslagapkyiehfskfspsplsmkqfldfgssnacektsftflrqelpvr
lanimkeinllpdrvlstpsvqlvqswyvqslldimefldkdpedhrtlsqftdalvtir
nrhndvvptmaqgvleykdtygddpvsnqniqyfldrfylsrisirmlinqhtlifdgst
npahpkhigsidpncsvsdvvkdaydmakllcdkyymaspdleiqevnatnatqpihmvy
vpshlyhmlfelfknamratveshessltlppikimvalgeedlsikmsdrgggvplrki
erlfsymystaptpqpgtggtplagfgyglpisrlyakyfqgdlqlfsmegfgtdaviyl
kalstdsverlpvynksawrhyqtiqeagdwcvpstepkntstyrvs

    Sequence, based on observed residues (ATOM records): (download) 
    >3crlB (B:)
slagapkyiehfskfspsplsmkqfldfgssnacektsftflrqelpvrlanimkeinll
pdrvlstpsvqlvqswyvqslldimefldkdpedhrtlsqftdalvtirnrhndvvptma
qgvleykdtygddpvsnqniqyfldrfylsrisirmlinqhtlifdgstnpahpkhigsi
dpncsvsdvvkdaydmakllcdkyymaspdleiqevnatnatqpihmvyvpshlyhmlfe
lfknamratveshessltlppikimvalgeedlsikmsdrgggvplrkierlfsymysta
plagfgyglpisrlyakyfqgdlqlfsmegfgtdaviylkalstdsverlpvynksawrh
yqtiqeagdwcvpstepkntsty

  • Chain 'C':
    Sequence; same for both SEQRES and ATOM records: (download) 
    >3crlC (C:)
sypphmqvllpalsptmtmgtvqrwekkvgeklsegdllaeietdkatigfevqeegyla
kilvpegtrdvplgtplciivekeadi

  • Chain 'D':
    Sequence; same for both SEQRES and ATOM records: (download) 
    >3crlD (D:)
sypphmqvllpalsptmtmgtvqrwekkvgeklsegdllaeietdkatigfevqeegyla
kilvpegtrdvplgtplciivekeadi