PDB entry 3crh
View 3crh on RCSB PDB site
Description: Crystal structure of human fibroblast growth factor-1 with mutations Glu81Ser and Lys101Ala
Class: hormone
Keywords: crystal packing, Angiogenesis, Developmental protein, Differentiation, Growth factor, Heparin-binding, Mitogen, HORMONE
Deposited on
2008-04-07, released
2009-02-17
The last revision prior to the SCOPe 2.05 freeze date was dated
2011-07-13, with a file datestamp of
2011-05-08.
Experiment type: XRAY
Resolution: 2.15 Å
R-factor: 0.183
AEROSPACI score: 0.42
(click here for full SPACI score report)
Chains and heterogens:
- Chain 'A':
Compound: heparin-binding growth factor 1
Species: Homo sapiens [TaxId:9606]
Gene: FGF1, FGFA
Database cross-references and differences (RAF-indexed):
- Uniprot P05230
- engineered (86)
- engineered (106)
Domains in SCOPe 2.05: d3crha_ - Chain 'B':
Compound: heparin-binding growth factor 1
Species: Homo sapiens [TaxId:9606]
Gene: FGF1, FGFA
Database cross-references and differences (RAF-indexed):
- Uniprot P05230
- engineered (86)
- engineered (106)
Domains in SCOPe 2.05: d3crhb_ - Heterogens: SO4, HOH
PDB Chain Sequences:
- Chain 'A':
Sequence, based on SEQRES records: (download)
>3crhA (A:)
hhhhhhfnlppgnykkpkllycsngghflrilpdgtvdgtrdrsdqhiqlqlsaesvgev
yikstetgqylamdtdgllygsqtpnseclflerleenhyntyiskahaeknwfvglkkn
gsckrgprthygqkailflplpvssd
Sequence, based on observed residues (ATOM records): (download)
>3crhA (A:)
hhhhhfnlppgnykkpkllycsngghflrilpdgtvdgtrdrsdqhiqlqlsaesvgevy
ikstetgqylamdtdgllygsqtpnseclflerleenhyntyiskahaeknwfvglkkng
sckrgprthygqkailflplpv
- Chain 'B':
Sequence, based on SEQRES records: (download)
>3crhB (B:)
hhhhhhfnlppgnykkpkllycsngghflrilpdgtvdgtrdrsdqhiqlqlsaesvgev
yikstetgqylamdtdgllygsqtpnseclflerleenhyntyiskahaeknwfvglkkn
gsckrgprthygqkailflplpvssd
Sequence, based on observed residues (ATOM records): (download)
>3crhB (B:)
hhhhhfnlppgnykkpkllycsngghflrilpdgtvdgtrdrsdqhiqlqlsaesvgevy
ikstetgqylamdtdgllygsqtpnseclflerleenhyntyiskahaeknwfvglkkng
sckrgprthygqkailflplpv