PDB entry 3cos

View 3cos on RCSB PDB site
Description: crystal structure of human class ii alcohol dehydrogenase (adh4) in complex with nad and zn
Deposited on 2008-03-29, released 2008-04-15
The last revision was dated 2017-10-25, with a file datestamp of 2017-10-20.
Experiment type: XRAY
Resolution: 2.1 Å
R-factor: N/A
AEROSPACI score: 0.29 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: Alcohol dehydrogenase 4
    Species: Homo sapiens [TaxId:9606]
    Gene: ADH4
    Database cross-references and differences (RAF-indexed):
  • Chain 'B':
    Compound: Alcohol dehydrogenase 4
    Species: Homo sapiens [TaxId:9606]
    Gene: ADH4
    Database cross-references and differences (RAF-indexed):
  • Chain 'C':
    Compound: Alcohol dehydrogenase 4
    Species: Homo sapiens [TaxId:9606]
    Gene: ADH4
    Database cross-references and differences (RAF-indexed):
  • Chain 'D':
    Compound: Alcohol dehydrogenase 4
    Species: Homo sapiens [TaxId:9606]
    Gene: ADH4
    Database cross-references and differences (RAF-indexed):
    • Uniprot P08319 (1-380)
      • expression tag (0)
  • Heterogens: ZN, NAD, EDO, ACY, HOH

PDB Chain Sequences:
This PDB entry is not classified in SCOPe 2.08, so the chain sequences below are not included in the ASTRAL sequence sets.

  • Chain 'A':
    Sequence, based on SEQRES records:
    >3cosA (A:)
smgtkgkvikckaaiaweagkplcieevevappkahevriqiiatslchtdatvidskfe
glafpvivgheaagivesigpgvtnvkpgdkviplyaplcrkckfclspltnlcgkisnl
kspasdqqlmedktsrftckgkpvyhffgtstfsqytvvsdinlakidddanlervcllg
cgfstgygaainnakvtpgstcavfglggvglsavmgckaagasriigidinsekfvkak
algatdclnprdlhkpiqeviieltkggvdfaldcaggsetmkaaldcttagwgsctfig
vaagskgltvfpeeliigrtingtffggwksvdsipklvtdyknkkfnldalvthtlpfd
kiseafdlmnqgksirtilif

    Sequence, based on observed residues (ATOM records):
    >3cosA (A:)
gtkgkvikckaaiaweagkplcieevevappkahevriqiiatslchtdatvidskfegl
afpvivgheaagivesigpgvtnvkpgdkviplyaplcrkckfclspltnlcgkisnlks
pasdqqlmedktsrftckgkpvyhffgtstfsqytvvsdinlakidddanlervcllgcg
fstgygaainnakvtpgstcavfglggvglsavmgckaagasriigidinsekfvkakal
gatdclnprdlhkpiqeviieltkggvdfaldcaggsetmkaaldcttagwgsctfigva
agskgltvfpeeliigrtingtffggwksvdsipklvtdyknkkfnldalvthtlpfdki
seafdlmnqgksirtilif

  • Chain 'B':
    Sequence, based on SEQRES records:
    >3cosB (B:)
smgtkgkvikckaaiaweagkplcieevevappkahevriqiiatslchtdatvidskfe
glafpvivgheaagivesigpgvtnvkpgdkviplyaplcrkckfclspltnlcgkisnl
kspasdqqlmedktsrftckgkpvyhffgtstfsqytvvsdinlakidddanlervcllg
cgfstgygaainnakvtpgstcavfglggvglsavmgckaagasriigidinsekfvkak
algatdclnprdlhkpiqeviieltkggvdfaldcaggsetmkaaldcttagwgsctfig
vaagskgltvfpeeliigrtingtffggwksvdsipklvtdyknkkfnldalvthtlpfd
kiseafdlmnqgksirtilif

    Sequence, based on observed residues (ATOM records):
    >3cosB (B:)
gtkgkvikckaaiaweagkplcieevevappkahevriqiiatslchtdatvidskfegl
afpvivgheaagivesigpgvtnvkpgdkviplyaplcrkckfclspltnlcgkisnlks
pasdqqlmedktsrftckgkpvyhffgtstfsqytvvsdinlakidddanlervcllgcg
fstgygaainnakvtpgstcavfglggvglsavmgckaagasriigidinsekfvkakal
gatdclnprdlhkpiqeviieltkggvdfaldcaggsetmkaaldcttagwgsctfigva
agskgltvfpeeliigrtingtffggwksvdsipklvtdyknkkfnldalvthtlpfdki
seafdlmnqgksirtilif

  • Chain 'C':
    Sequence, based on SEQRES records:
    >3cosC (C:)
smgtkgkvikckaaiaweagkplcieevevappkahevriqiiatslchtdatvidskfe
glafpvivgheaagivesigpgvtnvkpgdkviplyaplcrkckfclspltnlcgkisnl
kspasdqqlmedktsrftckgkpvyhffgtstfsqytvvsdinlakidddanlervcllg
cgfstgygaainnakvtpgstcavfglggvglsavmgckaagasriigidinsekfvkak
algatdclnprdlhkpiqeviieltkggvdfaldcaggsetmkaaldcttagwgsctfig
vaagskgltvfpeeliigrtingtffggwksvdsipklvtdyknkkfnldalvthtlpfd
kiseafdlmnqgksirtilif

    Sequence, based on observed residues (ATOM records):
    >3cosC (C:)
gtkgkvikckaaiaweagkplcieevevappkahevriqiiatslchtdatvidskfegl
afpvivgheaagivesigpgvtnvkpgdkviplyaplcrkckfclspltnlcgkisnlks
pasdqqlmedktsrftckgkpvyhffgtstfsqytvvsdinlakidddanlervcllgcg
fstgygaainnakvtpgstcavfglggvglsavmgckaagasriigidinsekfvkakal
gatdclnprdlhkpiqeviieltkggvdfaldcaggsetmkaaldcttagwgsctfigva
agskgltvfpeeliigrtingtffggwksvdsipklvtdyknkkfnldalvthtlpfdki
seafdlmnqgksirtilif

  • Chain 'D':
    Sequence; same for both SEQRES and ATOM records:
    >3cosD (D:)
smgtkgkvikckaaiaweagkplcieevevappkahevriqiiatslchtdatvidskfe
glafpvivgheaagivesigpgvtnvkpgdkviplyaplcrkckfclspltnlcgkisnl
kspasdqqlmedktsrftckgkpvyhffgtstfsqytvvsdinlakidddanlervcllg
cgfstgygaainnakvtpgstcavfglggvglsavmgckaagasriigidinsekfvkak
algatdclnprdlhkpiqeviieltkggvdfaldcaggsetmkaaldcttagwgsctfig
vaagskgltvfpeeliigrtingtffggwksvdsipklvtdyknkkfnldalvthtlpfd
kiseafdlmnqgksirtilif