PDB entry 3clz

View 3clz on RCSB PDB site
Description: The set and ring associated (SRA) domain of UHRF1 bound to methylated DNA
Class: ligase
Keywords: CELL CYCLE, DNA DAMAGE, DNA REPAIR, DNA-BINDING, BASE FLIPPING, LIGASE, METAL BINDING, NUCLEASE, DNA REPLICATION, TRANSCRIPTIONAL SILENCING, CHROMATIN, PHOSPHORYLATION, TRANSCRIPTION, TRANSCRIPTION REGULATION, UBL CONJUGATION, UBL CONJUGATION PATHWAY, ZINC, ZINC-FINGER, STRUCTURAL GENOMICS CONSORTIUM, SGC, Metal-binding, Nucleus, Phosphoprotein, Polymorphism
Deposited on 2008-03-20, released 2008-04-29
The last revision prior to the SCOPe 2.08 freeze date was dated 2009-02-24, with a file datestamp of 2009-02-03.
Experiment type: XRAY
Resolution: 2.2 Å
R-factor: 0.191
AEROSPACI score: 0.38 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: E3 ubiquitin-protein ligase UHRF1
    Species: Homo sapiens [TaxId:9606]
    Gene: UHRF1, ICBP90, NP95, RNF106
    Database cross-references and differences (RAF-indexed):
    • Uniprot Q96T88 (Start-204)
      • expression tag (205-206)
    Domains in SCOPe 2.08: d3clza2, d3clza3
  • Chain 'B':
    Compound: E3 ubiquitin-protein ligase UHRF1
    Species: Homo sapiens [TaxId:9606]
    Gene: UHRF1, ICBP90, NP95, RNF106
    Database cross-references and differences (RAF-indexed):
    • Uniprot Q96T88 (Start-204)
      • expression tag (205-211)
    Domains in SCOPe 2.08: d3clzb2, d3clzb3
  • Chain 'C':
    Compound: E3 ubiquitin-protein ligase UHRF1
    Species: Homo sapiens [TaxId:9606]
    Gene: UHRF1, ICBP90, NP95, RNF106
    Database cross-references and differences (RAF-indexed):
    • Uniprot Q96T88 (Start-204)
      • expression tag (205-206)
    Domains in SCOPe 2.08: d3clzc2, d3clzc3
  • Chain 'D':
    Compound: E3 ubiquitin-protein ligase UHRF1
    Species: Homo sapiens [TaxId:9606]
    Gene: UHRF1, ICBP90, NP95, RNF106
    Database cross-references and differences (RAF-indexed):
    • Uniprot Q96T88 (Start-204)
      • expression tag (205-211)
    Domains in SCOPe 2.08: d3clzd2, d3clzd3
  • Chain 'E':
    Compound: 5'-d(*dgp*dgp*dgp*dcp*dcp*(5cm)p*dgp*dcp*dap*dgp*dgp*dg)-3'
  • Chain 'F':
    Compound: 5'-d(*dcp*dcp*dcp*dtp*dgp*dcp*dgp*dgp*dgp*dcp*dcp*dc)-3'
  • Chain 'G':
    Compound: 5'-d(*dgp*dgp*dgp*dcp*dcp*(5cm)p*dgp*dcp*dap*dgp*dgp*dg)-3'
  • Chain 'H':
    Compound: 5'-d(*dcp*dcp*dcp*dtp*dgp*dcp*dgp*dgp*dgp*dcp*dcp*dc)-3'
  • Chain 'I':
    Compound: 5'-d(*dgp*dgp*dgp*dcp*dcp*(5cm)p*dgp*dcp*dap*dgp*dgp*dg)-3'
  • Chain 'J':
    Compound: 5'-d(*dcp*dcp*dcp*dtp*dgp*dcp*dgp*dgp*dgp*dcp*dcp*dc)-3'
  • Chain 'K':
    Compound: 5'-d(*dgp*dgp*dgp*dcp*dcp*(5cm)p*dgp*dcp*dap*dgp*dgp*dg)-3'
  • Chain 'L':
    Compound: 5'-d(*dcp*dcp*dcp*dtp*dgp*dcp*dgp*dgp*dgp*dcp*dcp*dc)-3'
  • Heterogens: HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download) 
    >3clzA (A:)
mpsnhygpipgipvgtmwrfrvqvsesgvhrphvagihgrsndgayslvlaggyeddvdh
gnfftytgsggrdlsgnkrtaeqscdqkltntnralalncfapindqegaeakdwrsgkp
vrvvrnvkggknskyapaegnrydgiykvvkywpekgksgflvwryllrrdddepgpwtk
egkdrikklgltmqypegylealanahhhhhh

    Sequence, based on observed residues (ATOM records): (download) 
    >3clzA (A:)
nhygpipgipvgtmwrfrvqvsesgvhrphvagihgrsndgayslvlaggyeddvdhgnf
ftytgsggrdlsgnkrtaeqscdqkltntnralalncfapindqegaeakdwrsgkpvrv
vrnvkggknskyapaegnrydgiykvvkywpekgksgflvwryllrrdddepgpwtkegk
drikklgltmqypegylealanah

  • Chain 'B':
    Sequence, based on SEQRES records: (download) 
    >3clzB (B:)
mpsnhygpipgipvgtmwrfrvqvsesgvhrphvagihgrsndgayslvlaggyeddvdh
gnfftytgsggrdlsgnkrtaeqscdqkltntnralalncfapindqegaeakdwrsgkp
vrvvrnvkggknskyapaegnrydgiykvvkywpekgksgflvwryllrrdddepgpwtk
egkdrikklgltmqypegylealanahhhhhh

    Sequence, based on observed residues (ATOM records): (download) 
    >3clzB (B:)
snhygpipgipvgtmwrfrvqvsesgvhrphvagihgrsndgayslvlaggyeddvdhgn
fftytgsggrdlsgnkrtaeqscdqkltntnralalncfapindqegaeakdwrsgkpvr
vvrnvkggknskyapaegnrydgiykvvkywpekgksgflvwryllrrdddepgpwtkeg
kdrikklgltmqypegylealanahhhhhh

  • Chain 'C':
    Sequence, based on SEQRES records: (download) 
    >3clzC (C:)
mpsnhygpipgipvgtmwrfrvqvsesgvhrphvagihgrsndgayslvlaggyeddvdh
gnfftytgsggrdlsgnkrtaeqscdqkltntnralalncfapindqegaeakdwrsgkp
vrvvrnvkggknskyapaegnrydgiykvvkywpekgksgflvwryllrrdddepgpwtk
egkdrikklgltmqypegylealanahhhhhh

    Sequence, based on observed residues (ATOM records): (download) 
    >3clzC (C:)
nhygpipgipvgtmwrfrvqvsesgvhrphvagihgrsndgayslvlaggyeddvdhgnf
ftytgsggrdlsgnkrtaeqscdqkltntnralalncfapindqegaeakdwrsgkpvrv
vrnvkggknskyapaegnrydgiykvvkywpekgksgflvwryllrrdddepgpwtkegk
drikklgltmqypegylealanah

  • Chain 'D':
    Sequence, based on SEQRES records: (download) 
    >3clzD (D:)
mpsnhygpipgipvgtmwrfrvqvsesgvhrphvagihgrsndgayslvlaggyeddvdh
gnfftytgsggrdlsgnkrtaeqscdqkltntnralalncfapindqegaeakdwrsgkp
vrvvrnvkggknskyapaegnrydgiykvvkywpekgksgflvwryllrrdddepgpwtk
egkdrikklgltmqypegylealanahhhhhh

    Sequence, based on observed residues (ATOM records): (download) 
    >3clzD (D:)
nhygpipgipvgtmwrfrvqvsesgvhrphvagihgrsndgayslvlaggyeddvdhgnf
ftytgsggrdlsgnkrtaeqscdqkltntnralalncfapindqegaeakdwrsgkpvrv
vrnvkggknskyapaegnrydgiykvvkywpekgksgflvwryllrrdddepgpwtkegk
drikklgltmqypegylealanahhhhhh

  • Chain 'E':
    No sequence available.

  • Chain 'F':
    No sequence available.

  • Chain 'G':
    No sequence available.

  • Chain 'H':
    No sequence available.

  • Chain 'I':
    No sequence available.

  • Chain 'J':
    No sequence available.

  • Chain 'K':
    No sequence available.

  • Chain 'L':
    No sequence available.