PDB entry 3cly
View 3cly on RCSB PDB site
Description: Crystal Structure of FGF Receptor 2 (FGFR2) Kinase Domains Trapped in Trans-Phosphorylation Reaction
Class: transferase
Keywords: Kinase Domain, Trans-Phosphorylation, ATP-binding, Disease mutation, Ectodermal dysplasia, Glycoprotein, Heparin-binding, Immunoglobulin domain, Lacrimo-auriculo-dento-digital syndrome, Membrane, Nucleotide-binding, Phosphoprotein, Receptor, Secreted, Transferase, Transmembrane, Tyrosine-protein kinase
Deposited on
2008-03-20, released
2009-02-03
The last revision prior to the SCOPe 2.05 freeze date was dated
2012-03-07, with a file datestamp of
2012-03-02.
Experiment type: XRAY
Resolution: 2 Å
R-factor: 0.216
AEROSPACI score: 0.44
(click here for full SPACI score report)
Chains and heterogens:
- Chain 'A':
Compound: Fibroblast growth factor receptor 2
Species: Homo sapiens [TaxId:9606]
Gene: FGFR2, BEK, KGFR, KSAM
Database cross-references and differences (RAF-indexed):
Domains in SCOPe 2.05: d3clya_ - Heterogens: MG, ACP, HOH
PDB Chain Sequences:
- Chain 'A':
Sequence, based on SEQRES records: (download)
>3clyA (A:)
mgsshhhhhhsqdpmlagvseyelpedpkwefprdkltlgkplgegafgqvvmaeavgid
kdkpkeavtvavkmlkddatekdlsdlvsememmkmigkhkniinllgactqdgplyviv
eyaskgnlreylrarrppgmeysydinrvpeeqmtfkdlvsctyqlargmeylasqkcih
rdlaarnvlvtennvmkiadfglardinnidyykkttngrlpvkwmapealfdrvythqs
dvwsfgvlmweiftlggspypgipveelfkllkeghrmdkpanctnelymmmrdcwhavp
sqrptfkqlvedldriltlttneeyldlsqpleq
Sequence, based on observed residues (ATOM records): (download)
>3clyA (A:)
lpedpkwefprdkltlgkplgegafgqvvmaeavgidkdkpkeavtvavkmlkddatekd
lsdlvsememmkmigkhkniinllgactqdgplyviveyaskgnlreylrarreeqmtfk
dlvsctyqlargmeylasqkcihrdlaarnvlvtennvmkiadfglardinnidyykktt
ngrlpvkwmapealfdrvythqsdvwsfgvlmweiftlggspypgipveelfkllkeghr
mdkpanctnelymmmrdcwhavpsqrptfkqlvedldriltlttneeyldl