PDB entry 3clb

View 3clb on RCSB PDB site
Description: Structure of bifunctional TcDHFR-TS in complex with TMQ
Deposited on 2008-03-18, released 2009-01-06
The last revision was dated 2011-07-13, with a file datestamp of 2011-05-08.
Experiment type: XRAY
Resolution: 3 Å
R-factor: 0.209
AEROSPACI score: 0.24 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: dhfr-ts
    Species: Trypanosoma cruzi [TaxId:5693]
    Database cross-references and differences (RAF-indexed):
    • Uniprot Q27793
      • see remark 999 (31)
      • see remark 999 (54)
      • see remark 999 (136)
  • Chain 'B':
    Compound: dhfr-ts
    Species: Trypanosoma cruzi [TaxId:5693]
    Database cross-references and differences (RAF-indexed):
    • Uniprot Q27793
      • see remark 999 (31)
      • see remark 999 (54)
      • see remark 999 (136)
  • Chain 'C':
    Compound: dhfr-ts
    Species: Trypanosoma cruzi [TaxId:5693]
    Database cross-references and differences (RAF-indexed):
    • Uniprot Q27793 (0-End)
      • see remark 999 (31)
      • see remark 999 (54)
      • see remark 999 (136)
  • Chain 'D':
    Compound: dhfr-ts
    Species: Trypanosoma cruzi [TaxId:5693]
    Database cross-references and differences (RAF-indexed):
    • Uniprot Q27793 (0-End)
      • see remark 999 (31)
      • see remark 999 (54)
      • see remark 999 (136)
  • Heterogens: SO4, NAP, TMQ, EDO, HOH

PDB Chain Sequences:
This PDB entry is not classified in SCOPe 2.08, so the chain sequences below are not included in the ASTRAL sequence sets.

  • Chain 'A':
    Sequence, based on SEQRES records:
    >3clbA (A:)
mslfkirmpetvaegtrlalrafslvvavderggigdgrsipwnvpedmkffrdvttklr
gknvkpspakrnavvmgrktwdsippkfrplpgrlnvvlsstlttqhlldglpdeekrnl
hadsivavnggleqalqllaspnytpsietvycigggsvyaealrppcvhllqaiyrtti
rasesscsvffrvpesgteaaagiewqretiseeltsangnetkyyfekliprnreeeqy
lslvdriiregnvkhdrtgvgtlsifgaqmrfslrnnrlpllttkrvfwrgvceellwfl
rgetyakklsdkgvhiwddngsrafldsrglteyeemdlgpvygfqwrhfgaaythhdan
ydgqgvdqikaivetlktnpddrrmlftawnpsalprmalppchllaqfyvsngelscml
yqrscdmglgvpfniasyalltiliakatglrpgelvhtlgdahvysnhvepcneqlkrv
prafpylvfrrerefledyeegdmevidyapyppismkmav

    Sequence, based on observed residues (ATOM records):
    >3clbA (A:)
slfkirmpetvaegtrlalrafslvvavderggigdgrsipwnvpedmkffrdvttklrg
knvkpspakrnavvmgrktwdsippkfrplpgrlnvvlsstlttqhlldglpdehadsiv
avnggleqalqllaspnytpsietvycigggsvyaealrppcvhllqaiyrttirasess
csvffrvpesgteaaagiewqretiseeltsangnetkyyfekliprnreeeqylslvdr
iiregnvkhdrtgvgtlsifgaqmrfslrnnrlpllttkrvfwrgvceellwflrgetya
kklsdkgvhiwddngsrafldsrglteyeemdlgpvygfqwrhfgaaythhdanydgqgv
dqikaivetlktnpddrrmlftawnpsalprmalppchllaqfyvsngelscmlyqrscd
mglgvpfniasyalltiliakatglrpgelvhtlgdahvysnhvepcneqlkrvprafpy
lvfrrerefledyeegdmevidyapyppis

  • Chain 'B':
    Sequence, based on SEQRES records:
    >3clbB (B:)
mslfkirmpetvaegtrlalrafslvvavderggigdgrsipwnvpedmkffrdvttklr
gknvkpspakrnavvmgrktwdsippkfrplpgrlnvvlsstlttqhlldglpdeekrnl
hadsivavnggleqalqllaspnytpsietvycigggsvyaealrppcvhllqaiyrtti
rasesscsvffrvpesgteaaagiewqretiseeltsangnetkyyfekliprnreeeqy
lslvdriiregnvkhdrtgvgtlsifgaqmrfslrnnrlpllttkrvfwrgvceellwfl
rgetyakklsdkgvhiwddngsrafldsrglteyeemdlgpvygfqwrhfgaaythhdan
ydgqgvdqikaivetlktnpddrrmlftawnpsalprmalppchllaqfyvsngelscml
yqrscdmglgvpfniasyalltiliakatglrpgelvhtlgdahvysnhvepcneqlkrv
prafpylvfrrerefledyeegdmevidyapyppismkmav

    Sequence, based on observed residues (ATOM records):
    >3clbB (B:)
slfkirmpetvaegtrlalrafslvvavderggigdgrsipwnvpedmkffrdvttklrg
knvkpspakrnavvmgrktwdsippkfrplpgrlnvvlsstlttqhlldglpdeadsiva
vnggleqalqllaspnytpsietvycigggsvyaealrppcvhllqaiyrttirasessc
svffrvpesgteaaagiewqretiseeltsangnetkyyfekliprnreeeqylslvdri
iregnvkhdrtgvgtlsifgaqmrfslrnnrlpllttkrvfwrgvceellwflrgetyak
klsdkgvhiwddngsrafldsrglteyeemdlgpvygfqwrhfgaaythhdanydgqgvd
qikaivetlktnpddrrmlftawnpsalprmalppchllaqfyvsngelscmlyqrscdm
glgvpfniasyalltiliakatglrpgelvhtlgdahvysnhvepcneqlkrvprafpyl
vfrrerefledyeegdmevidyapyppi

  • Chain 'C':
    Sequence, based on SEQRES records:
    >3clbC (C:)
mslfkirmpetvaegtrlalrafslvvavderggigdgrsipwnvpedmkffrdvttklr
gknvkpspakrnavvmgrktwdsippkfrplpgrlnvvlsstlttqhlldglpdeekrnl
hadsivavnggleqalqllaspnytpsietvycigggsvyaealrppcvhllqaiyrtti
rasesscsvffrvpesgteaaagiewqretiseeltsangnetkyyfekliprnreeeqy
lslvdriiregnvkhdrtgvgtlsifgaqmrfslrnnrlpllttkrvfwrgvceellwfl
rgetyakklsdkgvhiwddngsrafldsrglteyeemdlgpvygfqwrhfgaaythhdan
ydgqgvdqikaivetlktnpddrrmlftawnpsalprmalppchllaqfyvsngelscml
yqrscdmglgvpfniasyalltiliakatglrpgelvhtlgdahvysnhvepcneqlkrv
prafpylvfrrerefledyeegdmevidyapyppismkmav

    Sequence, based on observed residues (ATOM records):
    >3clbC (C:)
mslfkirmpetvaegtrlalrafslvvavderggigdgrsipwnvpedmkffrdvttklr
gknvkpspakrnavvmgrktwdsippkfrplpgrlnvvlsstlttqhlldglpdehadsi
vavnggleqalqllaspnytpsietvycigggsvyaealrppcvhllqaiyrttirases
scsvffrvpesgteaaagiewqretiseeltsangnetkyyfekliprnreeeqylslvd
riiregnvkhdrtgvgtlsifgaqmrfslrnnrlpllttkrvfwrgvceellwflrgety
akklsdkgvhiwddngsrafldsrglteyeemdlgpvygfqwrhfgaaythhdanydgqg
vdqikaivetlktnpddrrmlftawnpsalprmalppchllaqfyvsngelscmlyqrsc
dmglgvpfniasyalltiliakatglrpgelvhtlgdahvysnhvepcneqlkrvprafp
ylvfrrerefledyeegdmevidyapyppi

  • Chain 'D':
    Sequence, based on SEQRES records:
    >3clbD (D:)
mslfkirmpetvaegtrlalrafslvvavderggigdgrsipwnvpedmkffrdvttklr
gknvkpspakrnavvmgrktwdsippkfrplpgrlnvvlsstlttqhlldglpdeekrnl
hadsivavnggleqalqllaspnytpsietvycigggsvyaealrppcvhllqaiyrtti
rasesscsvffrvpesgteaaagiewqretiseeltsangnetkyyfekliprnreeeqy
lslvdriiregnvkhdrtgvgtlsifgaqmrfslrnnrlpllttkrvfwrgvceellwfl
rgetyakklsdkgvhiwddngsrafldsrglteyeemdlgpvygfqwrhfgaaythhdan
ydgqgvdqikaivetlktnpddrrmlftawnpsalprmalppchllaqfyvsngelscml
yqrscdmglgvpfniasyalltiliakatglrpgelvhtlgdahvysnhvepcneqlkrv
prafpylvfrrerefledyeegdmevidyapyppismkmav

    Sequence, based on observed residues (ATOM records):
    >3clbD (D:)
mslfkirmpetvaegtrlalrafslvvavderggigdgrsipwnvpedmkffrdvttklr
gknvkpspakrnavvmgrktwdsippkfrplpgrlnvvlsstlttqhlldglpdhadsiv
avnggleqalqllaspnytpsietvycigggsvyaealrppcvhllqaiyrttirasess
csvffrvpesgteaaagiewqretiseeltsangnetkyyfekliprnreeeqylslvdr
iiregnvkhdrtgvgtlsifgaqmrfslrnnrlpllttkrvfwrgvceellwflrgetya
kklsdkgvhiwddngsrafldsrglteyeemdlgpvygfqwrhfgaaythhdanydgqgv
dqikaivetlktnpddrrmlftawnpsalprmalppchllaqfyvsngelscmlyqrscd
mglgvpfniasyalltiliakatglrpgelvhtlgdahvysnhvepcneqlkrvprafpy
lvfrrerefledyeegdmevidyapyppi