PDB entry 3cl3

View 3cl3 on RCSB PDB site
Description: crystal structure of a vflip-ikkgamma complex: insights into viral activation of the ikk signalosome
Deposited on 2008-03-18, released 2008-06-17
The last revision was dated 2018-06-13, with a file datestamp of 2018-06-08.
Experiment type: XRAY
Resolution: 3.2 Å
R-factor: N/A
AEROSPACI score: 0.11 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: orf k13
    Species: Human gammaherpesvirus 8 [TaxId:37296]
    Gene: vFLIP
    Database cross-references and differences (RAF-indexed):
  • Chain 'B':
    Compound: orf k13
    Species: Human gammaherpesvirus 8 [TaxId:37296]
    Gene: vFLIP
    Database cross-references and differences (RAF-indexed):
  • Chain 'D':
    Compound: NF-kappa-B essential modulator
    Species: Homo sapiens [TaxId:9606]
    Gene: IKBKG, FIP3, NEMO
    Database cross-references and differences (RAF-indexed):
  • Chain 'E':
    Compound: NF-kappa-B essential modulator
    Species: Homo sapiens [TaxId:9606]
    Gene: IKBKG, FIP3, NEMO
    Database cross-references and differences (RAF-indexed):

PDB Chain Sequences:
This PDB entry is not classified in SCOPe 2.08, so the chain sequences below are not included in the ASTRAL sequence sets.

  • Chain 'A':
    Sequence, based on SEQRES records:
    >3cl3A (A:)
gamgsmatyevlcevarklgtddrevvlfllnvfipqptlaqligalralkeegrltfpl
laeclfragrrdllrdllhldprflerhlagtmsyfspyqltvlhvdgelcardirslif
lskdtigsrstpqtflhwvycmenldllgptdvdalmsmlrslsrvdlqrqvqtlmglhl
sgp

    Sequence, based on observed residues (ATOM records):
    >3cl3A (A:)
atyevlcevarklgtddrevvlfllnvfipqptlaqligalralkeegrltfpllaeclf
ragrrdllrdllhldprflerhlagtmsyfspyqltvlhvdgelcardirsliflskdti
gsrstpqtflhwvycmenldllgptdvdalmsmlrslsrvdlqrqvqtlmgl

  • Chain 'B':
    Sequence, based on SEQRES records:
    >3cl3B (B:)
gamgsmatyevlcevarklgtddrevvlfllnvfipqptlaqligalralkeegrltfpl
laeclfragrrdllrdllhldprflerhlagtmsyfspyqltvlhvdgelcardirslif
lskdtigsrstpqtflhwvycmenldllgptdvdalmsmlrslsrvdlqrqvqtlmglhl
sgp

    Sequence, based on observed residues (ATOM records):
    >3cl3B (B:)
atyevlcevarklgtddrevvlfllnvfipqptlaqligalralkeegrltfpllaeclf
ragrrdllrdllhldprflerhlagtmsyfspyqltvlhvdgelcardirsliflsstpq
tflhwvycmenldllgptdvdalmsmlrslsrvdlqrqvqtlmgl

  • Chain 'D':
    Sequence, based on SEQRES records:
    >3cl3D (D:)
ghmasgslgelqesqsrleaatkecqalegraraaseqarqleserealqqqhsvqvdql
rmqgqsveaalrmerqaaseekrklaqlqvayhqlfqeydnhikssvvgserkrgmqled
lkqqlqqaee

    Sequence, based on observed residues (ATOM records):
    >3cl3D (D:)
qqhsvqvdqlrmqgqsveaalrmerqaaseekrklaqlqvayhqlfqeydnhikssvvg

  • Chain 'E':
    Sequence, based on SEQRES records:
    >3cl3E (E:)
ghmasgslgelqesqsrleaatkecqalegraraaseqarqleserealqqqhsvqvdql
rmqgqsveaalrmerqaaseekrklaqlqvayhqlfqeydnhikssvvgserkrgmqled
lkqqlqqaee

    Sequence, based on observed residues (ATOM records):
    >3cl3E (E:)
svqvdqlrmqgqsveaalrmerqaaseekrklaqlqvayhqlfqeydnhikssvvgse