PDB entry 3ckx

View 3ckx on RCSB PDB site
Description: Crystal structure of sterile 20-like kinase 3 (MST3, STK24) in complex with staurosporine
Class: transferase
Keywords: STRUCTURAL GENOMICS, PSI-2, PROTEIN STRUCTURE INITIATIVE, New York SGX Research Center for Structural Genomics, NYSGXRC, PROTEIN KINASE, MST3, STK24, STERILE 20-LIKE KINASE, STAUROSPORINE, Alternative splicing, ATP-binding, Cytoplasm, Nucleotide-binding, Phosphoprotein, Serine/threonine-protein kinase, Transferase
Deposited on 2008-03-17, released 2008-04-29
The last revision prior to the SCOPe 2.05 freeze date was dated 2009-06-09, with a file datestamp of 2009-06-05.
Experiment type: XRAY
Resolution: 2.7 Å
R-factor: 0.204
AEROSPACI score: 0.28 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: Serine/threonine-protein kinase 24
    Species: Homo sapiens [TaxId:9606]
    Gene: STK24, MST3, STK3
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.05: d3ckxa_
  • Heterogens: STU, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download) 
    >3ckxA (A:)
msldpeelftklekigkgsfgevfkgidnrtqkvvaikiidleeaedeiediqqeitvls
qcdspyvtkyygsylkdtklwiimeylgggsaldllepgpldetqiatilreilkgldyl
hsekkihrdikaanvllsehgevkladfgvagqltdtqikrntfvgtpfwmapevikqsa
ydskadiwslgitaielargepphselhpmkvlflipknnpptlegnyskplkefveacl
nkepsfrptakellkhkfilrnakktsyltelidrykrwkaeqshddsssedsdaeeghh
hhhh

    Sequence, based on observed residues (ATOM records): (download) 
    >3ckxA (A:)
peelftklekigkgsfgevfkgidnrtqkvvaikiidleedeiediqqeitvlsqcdspy
vtkyygsylkdtklwiimeylgggsaldllepgpldetqiatilreilkgldylhsekki
hrdikaanvllsehgevkladfgvagqltdtqikrntfvgtpfwmapevikqsaydskad
iwslgitaielargepphselhpmkvlflipknnpptlegnyskplkefveaclnkepsf
rptakellkhkfilrnakktsyltelidrykrwkaeq